Current Green Chemistry - Online First
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Insight on Assessment of Toxins and Heavy Metals in Food Products - A Concise View on Analytical Approach and Methods
Authors: Pawan Kumar Goswami, Ranjeet Kumar and Dharmendra KumarAvailable online: 15 October 2025More LessIntroductionWith the globalization of food supply chains, food safety has emerged as a critical global concern impacting public health, well-being, and economic stability. Chemical contaminants such as mycotoxins and heavy metals pose significant health risks, necessitating advanced detection and monitoring strategies to ensure food safety.
MethodsA literature search was conducted in PubMed, Scopus, Web of Science, and ScienceDirect (2010-2025) using keywords like “food safety”, “heavy metals detection”, and “sample preparation…” Relevant studies were screened and reviewed to evaluate recent advancements in analytical technologies and sample preparation methods. Techniques such as SERS, ICP-MS, AFS, and AAS were assessed for sensitivity and accuracy, while novel preparation methods (microwave-assisted digestion, ultrasonic extraction, slurry, and direct solid sampling) were analyzed for efficiency. Speciation analysis of arsenic and mercury was also included to address bioavailability and toxicity.
ResultsAdvanced analytical methods showed superior sensitivity and rapid detection of trace contaminants. Microwave-assisted digestion and ultrasonic extraction enhanced sample preparation by reducing analyte loss and improving recovery rates. Direct solid sampling (e.g., graphite furnace AAS) and speciation analysis proved critical for assessing toxicological relevance.
DiscussionThese findings highlight the potential of integrating cutting-edge analytical technologies and improved sample preparation methods into routine food analysis. They address challenges of trace-level detection and offer strategies for mitigating chemical hazards in the food chain.
ConclusionAdopting advanced analytical and sample preparation techniques, supported by strengthened regulatory frameworks, is essential to ensuring food quality and safety and protecting public health globally.
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Biodegradable Food Materials for the Removal of Dyes from Aqueous Solution: Sustainable and Circular Approach for Food Waste Management
Available online: 05 August 2025More LessDye pollution is unsightly and harmful to the environment because it lowers oxygen levels in water and inhibits photosynthesis. The need for biodegradable polymers that can efficiently absorb pollutants is driven by the frequent failure of conventional treatment procedures to effectively remove dyes. The present study aimed to explore the applications of biodegradable natural components, including starch, cellulose, chitosan, and food waste derivatives, in removing dyes from wastewater. The review analysed relevant literature on biodegradable food materials for the removal of dyes from aqueous solution. The review articles were obtained through databases, including ScienceDirect, Scopus, PubMed, and Google Scholar. This review gathered relevant data, preferably from the last 10 years, on bioadsorbents for dye removal and waste management. Biodegradable adsorbents have shown great promise for dye removal due to their eco-friendliness, but their effectiveness depends on several factors. These include surface area, pH, and material modifications that enhance adsorption properties. Electrostatic interactions, ion exchange, hydrogen bonding, and π-π interactions play key roles in the dye adsorption process. Although these materials can be reused after dye removal, maintaining their efficacy over multiple cycles often requires chemical or thermal regeneration. Cost-effective scaling and the development of green regeneration techniques are still needed for practical applications. Dye removal is possible using biodegradable materials. Although these materials are effective with certain modifications, further research is needed to develop cost-effective scaling methods and environmentally friendly regeneration processes.
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Microwave-assisted Synthesis and Characterization of Calix[4]resorcinarene Schiff Base [C4RSB]
Authors: Parin H. Kanaiya, Vinod K. Jain and Mayank G. SharmaAvailable online: 05 August 2025More LessBackground/IntroductionCalix[4]resorcinarenes are macrocyclic hosts with wide-ranging applications in catalysis, molecular recognition, and materials science. Functionalization through Schiff base formation can enhance their stability, selectivity, and binding properties. Traditional synthetic approaches are often time-consuming, energy-intensive, and environmentally unfriendly.To develop a rapid, energy-efficient, and eco-friendly microwave-assisted protocol for synthesizing structurally diverse calix[4]resorcinarene Schiff base (C4RSB) derivatives in high yields, while adhering to green chemistry principles.
MethodA series of C4RSB derivatives was synthesized under mild conditions using ethanol as a green solvent and microwave-assisted heating. The reaction parameters were optimized to maximize yield and minimize energy consumption. The resulting compounds were characterized by NMR, FTIR, elemental analysis, and mass spectrometry to confirm structural fidelity, purity, and reproducibility.
ResultsThe microwave-assisted methodology yielded C4RSB derivatives in excellent yields (80–91%) with significant reductions in reaction time and energy usage compared to conventional methods. Spectroscopic analyses confirmed the successful formation of imine linkages and the preservation of the calix[4]resorcinarene framework. The methodology proved robust and reproducible, generating structurally consistent products.
DiscussionMicrowave-assisted synthesis of C4RSB derivatives achieved high yields with markedly reduced reaction times, underscoring its efficiency over conventional methods. The use of ethanol as a green solvent minimized environmental impact while maintaining product purity and structural integrity, as confirmed by spectroscopic analysis. Enhanced reaction kinetics under microwave irradiation facilitated rapid imine formation without thermal degradation, demonstrating the method’s suitability for sustainable, scalable macrocycle functionalization.
ConclusionMicrowave-assisted synthesis using ethanol as a green solvent provides an efficient, sustainable, and high-yielding route to C4RSB derivatives. This approach aligns with green chemistry principles and holds promise for the scalable production of functionalized calix[4]resorcinarenes for catalysis, molecular recognition, and advanced materials development.
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Production and Multidisciplinary Applications of Bioplastic: A Biodegradable and Eco-Friendly Alternative to Plastic
Authors: Ajesh Chauhan, Shivam Rajput, Rishabha Malviya and Sathvik Belagodu SridharAvailable online: 05 August 2025More LessThe versatility of plastics has led to their widespread use. The use of plastic has increased twentyfold in the previous half-century, and scientists anticipate that it will increase further in the subsequent two decades. Roughly 330 million metric tons of plastic is produced annually on a worldwide scale. A relatively recent and persistent issue in environmental management is the production, usage, and eventual disposal of plastics. Millions of animals perish annually, and soil fertility is diminished as a result of plastics building up in the ecosystem due to improper disposal. One solution to the environmental problems caused by polymers made from petrochemicals is the development of bioplastics, which are biodegradable and functionally equivalent to conventional plastics. Bioplastics and their derivatives have the potential to revolutionise environmental sustainability by reducing emissions of greenhouse gases and facilitating their widespread application. To find a long-term solution to the problem of plastic pollution, bioplastics must be developed further. It is crucial to raise public awareness to tackle plastic pollution in a sustainable manner. Concerns about pollution and the depletion of fossil fuel resources have prompted a dramatic increase in the study and creation of sustainable alternatives. Bioplastics made from sustainable plants provide a practical answer to these problems. This review article examined existing studies on the production, use, and multidisciplinary applications of bioplastics as biodegradable and environmentally friendly alternatives to conventional plastics. Research articles were collected from databases such as ScienceDirect, Scopus, PubMed, and Google Scholar. The review focused on highlighting the growing significance of bioplastics by analysing their production methods, diverse applications, and potential benefits across various sectors. This review will examine the many plant-based bioplastics, their production process, and their various uses in different sectors. Along with the opportunities and threats associated with bioplastics' potential future commercialisation, this paper explains the positive side along with the limitations of these environmentally friendly materials.
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Sustainable Tools for C-C and C-heteroatom Cross-coupling from Aryl Diazonium Salts
Authors: Atanu Mahata and Debasish KunduAvailable online: 22 July 2025More LessAromatic and heteroatomic diazonium salts constitute a significant class of very reactive electrophiles. In recent times, reactions of diazonium compounds under visible-light photocatalysis, microwave irradiation, and ball-milling strategies have been at the forefront of organic synthesis. The anions like tetrafluoroborate, mesylate, tosylate, disulfonamide, except for chloride and carboxylate, tethered with the aromatic rings of diazo frameworks, have rendered exceptional stability. The synthetic methodologies are highly advantageous in terms of regioselectivity of yields, broad substrate scope, excellent functional group tolerance, and high conversion ratio. These sustainable approaches not only reduce waste production, but also facilitate a ubiquitous eco-friendly protocol which enables strategies, transformations, and syntheses that are typically unachievable in solution. This current review article summarizes the recent developments of aryl diazonium compounds in the field of organic synthesis under ligand- and additive-less conditions. The sustainable techniques employed herein involve the use of non-toxic, low-cost, commercial-grade reagents, environmentally benign and greener solvents.
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Advanced Strategies for Enhancing Analytical Techniques of Solid Phase Microextraction: An Overview
Authors: Shivam Kumar, Ranjeet Kumar and Dharmendra KumarAvailable online: 18 July 2025More LessSolid-phase microextraction (SPME) is a popular technique for sample preparation, known for reducing the need for solvents and integrating well with chromatography instruments. Recent advancements focus on improving extraction efficiency through new coating materials. Despite improvements in analytical instruments, sample preparation remains a challenge, especially for detecting trace substances. This review explores the latest developments in SPME, particularly new coating materials, including nanomaterials like metal oxide nanoparticles, metal nanoparticles, carbon-based nanomaterials, and silica nanoparticles. These materials improve enrichment, analyte selectivity, and resistance to interference. The review also examines how analyte properties and coating composition affect extraction performance, helping researchers design better coatings. Additionally, the manuscript discusses modern applications of SPME, such as direct coupling with mass spectrometry and in vivo sampling, highlighting its growing importance in analytical fields. By summarizing recent innovations and applications, this review aims to provide valuable insights into developing more effective SPME techniques using advanced adsorbents for detecting and analyzing a wide range of substances.
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Coconut Husk for Second-generation Biofuel Production to Advance a Circular Economy
Authors: Tasmia Jahin Mim, Iftakhar Ahmad, Abdullah Al Noman, Divya Jain and Kuldeep SinghAvailable online: 04 July 2025More LessThe growing demand for sustainable energy alternatives has highlighted biofuel as a promising substitute for fossil fuels. Coconut husk, a byproduct of the coconut industry, remains an underused but abundant biomass resource with significant potential in biofuel production. This review provides a comprehensive overview of current technologies, challenges, and strategic opportunities in utilizing coconut husks for biofuel generation. It looks at thermochemical processes like pyrolysis, gasification, and combustion, as well as biochemical processes like anaerobic digestion, fermentation, and transesterification, focusing on how well they work, how much they can produce, and how they affect the environment. While coconut husk offers advantages in terms of biomass availability and calorific value, various technical, economic, and regulatory barriers must be addressed to unlock its full potential. Key challenges include feedstock processing, cost-effective conversion technologies, and regulatory and market limitations. Additionally, the review compares coconut husk to other biomass feedstocks, highlighting its sustainability and yield benefits. Case studies of regional programs in major coconut-producing areas provide insights into real-world applications and outcomes. The review also identifies critical research gaps in life cycle assessment, environmental impact, and policy development. Future directions emphasize technological advancements and policy measures to enhance the viability of coconut husks as biofuel sources. Overall, this review underscores coconut husk's potential as a sustainable biofuel feedstock, advocating for coordinated efforts to address existing challenges and advance renewable energy adoption.
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Exploring Nature's Pharmacy: A Comprehensive Review of Herbal Plants with Neuroprotective Properties
Authors: Dipesh Prajapati and Prabhat SinghAvailable online: 19 June 2025More LessNeurodegenerative disorders, such as Alzheimer's, Parkinson's, and Huntington's, are an increasing health concern worldwide due to their progressive nature and limited therapeutic choices. In search of innovative treatment techniques, herbal plants have received considerable attention due to their possible neuroprotective characteristics. For the literature review, several databases are used like Science Direct, PubMed, Springer, Frontiers, MDPI, Wiley, and Elsevier. This article offers a complete assessment of the neuroprotective properties of several herbal plants in preclinical and clinical research. This article discussed the active components, modes of action, and therapeutic potential of selected medicinal plants, including Ginkgo biloba, Bacopa monnieri, Curcuma longa, Panax ginseng, and Withania somnifera. These plants have a variety of neuroprotective properties, including antioxidant, anti-inflammatory, anti-apoptotic, and neurogenesis-promoting properties. Additionally, this review emphasizes the synergistic benefits reported when employing mixtures of these plants or combining them with conventional therapies. Despite encouraging results, existing research is sometimes restricted by small sample numbers, diversity in study designs, and lack of uniform dosing. Future studies should overcome these limitations through well-designed clinical studies and standardized extraction processes to fully understand the neuroprotective potential of these herbal plants. This review emphasizes the importance of incorporating herbal medicines into the development of novel treatments for neurodegenerative illnesses.
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Advancements in Bio-resource-based Polymers and Composites: Sustainable Alternatives to Non-biodegradable Plastics for a Greener Future: A Review
Available online: 09 May 2025More LessThere is an urgent need to investigate viable alternatives to address the significant environmental concerns created by the widespread use of non-biodegradable and non-recyclable synthetic plastics. Bioresource-based polymers from natural materials such as starch, cellulose, chitosan, lignin, and agricultural waste have shown great promise. These biodegradable, cost-effective, and environmentally benign materials address major concerns about the environmental and health effects of petroleum-based polyolefin plastics, which are widely utilized in the packaging, automotive, medical, and agricultural sectors. This review focuses on recent advances in bio-based polymers, blends, and composites reinforced with natural fibers and fillers, demonstrating their potential to replace traditional plastics. It also tackles the difficulties of cost reduction, performance improvement, and processing efficiency. Bioresource-based polymers have the potential to reduce plastic pollution and promote a more sustainable future by prioritizing innovation in material selection and manufacturing techniques.
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Recent Advances and Applications of Green Analytical Chemistry in Environmental Monitoring, Food Safety, and Pharmaceutical Analysis
Authors: Ashish Mehta, Anjana Sharma, Nitin Sharma, Lalit Kumar Tyagi and Vandana Arora SethiAvailable online: 08 May 2025More LessGreen analytical chemistry (GAC), which emphasizes environmental sustainability and responsibility, has now become an attractive choice for researchers. This review article provides a comprehensive introduction to the principles of GAC, which involve reducing excessive solvent consumption, toxicity of reagents, high power output, and complex sample treatment, making the analytical processes more efficient and effective. The article also highlights the recent developments in analytical techniques, like microfluidic devices [miniaturized extraction methods (combining LPME with DES, QuEChERS)], greenness evaluating tools (GAPI, AGREE, NEMI, Eco-scale, etc.) for data analysis, as well as metal-organic frameworks (like bimetallic MoF, Zn-MoF, etc.) to enhance detection sensitivity and specificity due to their larger surface area and superior physical properties as compared to traditional sorbents. Furthermore, these innovations are essential to meet the growing demand for less expensive and more environment-friendly methods for analysis. The various applications of GAC in the fields of food safety, environmental monitoring, and pharmaceutical analysis are discussed here, which might lead to a revolution in analytical techniques, improving health outcomes and fostering environmentally friendly societies.
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Synthesis of 2-(Bis(Phosphonomethyl)Amino)Ethane-1-sulfonic Acid Intercalated ZnAl Layered Double Hydroxide as an Efficient Adsorbent for Hg2+ Ions and Antimicrobial Agent
Available online: 24 April 2025More LessMercury is a pollutant of concern due to its negative influence on the environment and human health. Hydrotalcites, also known as layered double hydroxides, have attracted tremendous attention over the last few years in several fields such as healthcare and environmental remediation. Herein, a novel hybrid ZnAlLDH was synthesized to test its effect on mercury adsorption capacity. ZnAl-CO3/LDH synthesized using the co-precipitation method is grafted with a new phosphonic acid named2-(bis(phosphonomethyl)amino)ethane-1-sulfonic acid synthesized in our laboratory. Materials were characterized using textural, structural and morphological analysis. Mercury removal is measured by adsorption tests under relevant conditions. Parameters affecting the extraction process such as stirring speed, adsorbent dose, Hg2+ concentration, pH, ionic strength and temperature were fully studied and discussed. In effect, LDH intercalation with phosphonic acid and the optimization of mercury adsorption conditions improved the adsorption capacity of the prepared material by ca. 40%.87% of Hg2+ was successfully removed from aqueous solution. The hybrid LDH was also investigated in antibacterial and antifungal activities against Gram-negative (Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (A22), Pseudomonas aeruginosa (ATCC27853) and Acinetobacter baumannii (ATCC17978)), Gram-positive (Bacillus (ATCC11778), Staphylococcus aureus (ATCC25922), Staphylococcus aureus (ATCC43300) and Staphylococcus aureus (ATCC25923)) bacteria and Candida albicans (ATCC26790) fungus.
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