Recent Patents on Biotechnology - Online First
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Evaluation of Pharmacognostical and Anti-Ulcer Potential of Vernonia anthelmintica (L.) Willd Seed in Aspirin-Induced Ulcer Rats
Authors: Nidhi Bisht, Divya Jain, Neeraj Bainsal and Chandan SharmaAvailable online: 02 July 2025More LessBackground Vernonia anthelmintica (L.) Willd., commonly known as Kalijiri, has been used for the treatment of different ailments, including stomach aches, skin diseases, asthma, and cough, and is popular as a powerful anthelmintic agent. Aims This study aimed to evaluate the pharmacognostical, physicochemical, and phytochemical parameters along with the in-vivo antiulcer activity of the seeds of Vernonia an Read More
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Integrating Biosensors in Phytochemical Research: Challenges and Breakthroughs
Available online: 30 June 2025More LessBiosensors are devices that generate signals by interaction of biological elements and analytes, mainly based on their concentration. These are especially composed of enzymes or antibodies. They are associated with a physio-chemical transducer. Their rapid, simple, and real-time detection is of great importance in chemistry, analysis, and drug discovery and development. Phytoconstituents are biologically active compounds Read More
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Unveiling the Modern Therapeutic Properties and Folk Medicinal Riches of Rubia cordifolia
Authors: Diksha Sharma, Divya Jain and Deepika BhatiaAvailable online: 20 June 2025More LessRubia cordifolia (Manjishtha), a perennial herb of the Rubiaceae family, has been valued in traditional medicine for its diverse pharmacological properties. Predominantly cultivated in hilly regions, its roots have been historically used for their red pigment and therapeutic applications in Ayurveda. R. cordifolia has been traditionally employed for skin diseases, menstrual disorders, snake bites, herpes, eye ailments, haemo Read More
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Cognition, Diagnosis, and Treatment of Alzheimer’s Disease: A Review
Authors: Yuping Qin, Xiangxia Deng and Shuang ZhangAvailable online: 18 June 2025More LessAs the global population ages, the health of older adults has become a growing concern. Alzheimer’s disease (AD) is a common ailment affecting older adults, but the diagnosis and treatment of AD are difficult given our insufficient understanding of the disease. This review article and patents aim to provide reliable information for patients and their families by presenting a detailed overview of the pathogenic factors, diagnostic Read More
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Optimized Protocol for Sorghum Regeneration: Enhancing Embryogenic Callus Formation from Immature Inflorescences
Available online: 30 May 2025More LessAim This study aims to develop an efficient and reproducible in vitro protocol for high-frequency embryogenic callus induction and subsequent plant regeneration in multiple sorghum (Sorghum bicolor L. Moench) cultivars, thereby establishing a foundation for genetic transformation, mutation breeding, and other biotechnological applications aimed at enhancing sorghum crop improvement and productivity. Background Sorghu Read More
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Synthesis and Biological Properties of Formulated Skin Serum Containing Coelomic Fluid of Earthworm Eisenia fetida/andrei
Authors: Parisa Imeni, Mehdi Zarabi, Pegah Shakib and Ashkan DirbaziyanAvailable online: 07 May 2025More LessObjectives In this study, the coelomic fluid of Eisenia fetida/andrei species was used for the first time to prepare an anti-aging serum, and its antioxidant and antibacterial properties were investigated. In addition, its cytotoxicity on mouse fibroblast cells was measured as material for the production of natural anti-aging products. Materials and Methods This study investigates the antibacterial, antioxidant, and cytotoxic pro Read More
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Molecular Variation of Methicillin-resistant Staphylococcus haemolyticus Isolated from Patients in Ramadi City, Iraq
Available online: 30 April 2025More LessBackground The increasing prevalence of Staphylococcus haemolyticus infections in community and hospital settings presents a significant health challenge due to growing antibiotic resistance and biofilm formation. Objective This study aims to:(1) perform a molecular analysis of prevalent native strains in Anbar, Iraq, (2) differentiate between various pathogenic strains using multilocus sequence typing (MLST) to enhance e Read More
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Exploring the Two-Way Role: Biological and Anti-Epileptic Properties of Imidazole and 2-Mercaptobenzimidazole Derivatives
Authors: Geetika Goel and Jannat ul FirdousAvailable online: 25 April 2025More LessImidazole and 2-mercapto benzimidazole analogues are a group of molecules that have various biological activities and good therapeutic potential in the treatment of epilepsy. This review explores their dual role, focusing on their biological properties and anti-epileptic effects. A spectrum of biological activities is displayed by imidazole derivatives and 2- mercaptobenzimidazole, such as antifungal, antioxidant, anti-inflammato Read More
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Intellectual Property Rights Effects on India's Pharmaceutical Industry
Authors: Virendra S. Gomase, Suchita P. Dhamane and Swati C. JagdaleAvailable online: 21 April 2025More LessThe Indian pharmaceutical industry took full advantage of the “process patent regime”. It aggressively pursued the expansion of its market share by offering the most reasonably priced generic versions of pharmaceuticals to emerging and developing nations. The Indian government remained neutral over the implementation of the TRIPS agreement until 2005. Indian pharmaceutical patent law is distinct from legislation in othe Read More
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A Review on Adaption of Microbiomes to Polynuclear Aromatic Hydrocarbons: An Alternate Approach to Environment Sustainability
Authors: Kiran Dobhal, Ruchika Garg and Sayantan MukhoupadhyayAvailable online: 16 April 2025More LessPolycyclic aromatic hydrocarbons (PAHs) have been identified as catastrophic pollutants that can damage both the environment and human health. To restore a healthy surrounding, an environmental expert targeted the PAH contamination reduction strategy. Bioremediation techniques are overruling the conventional techniques due to their high disbursement and inefficient outcomes. Several PAHs, including Pyrene (PYR), C Read More
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Extraction and Characterization of Iturin A as a Key Factor in the Antagonism of Bacillus amyloliquefaciens M13RW01 Toward Pathogenic Fungi
Authors: Mahsa Aghaali Marnani, Mahboobeh Madani and Pegah ShakibAvailable online: 16 April 2025More LessBackground Bacillus amyloliquefaciens contains several fungal inhibitory compounds, such as peptides and lipopeptides, representing the remarkable potential for biotechnological, agricultural, and biopharmaceutical applications. Objectives This research aimed to extract and characterize iturin A as the key antagonism factor of Bacillus amyloliquefaciens M13RW01 toward pathogenic fungi, using HPLC and mas Read More
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Halo-tolerant Plant Growth Promoting Rhizobacteria Enhancing Mustard Seed Growth Under Salinity Stress for Sustainable Agriculture
Authors: Kusum Sharma, Pawan Kumar Sharma, S Rajendra Prasad, Anupam Singh, Divya Jain and Sachidanand SinghAvailable online: 11 February 2025More LessIntroduction Salinity is one of the primary environmental factors that significantly impact global crop production. Plant growth promoting rhizobacteria (PGPR) inoculation to crops improves the productivity of the crops. Method To develop a biofertilizer specifically for saline soil, bacteria were isolated from the rhizosphere of mustard plants along with the plant growth-promoting traits grown in saline soil (EC 6 dS Read More
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Pharmacological Approaches and Innovative Strategies for Individualized Patient Care
Authors: Amnesh Kumar Verma, Kuldeep Singh, Jeetendra Kumar Gupta, Shivendra Kumar and Divya JainAvailable online: 20 January 2025More LessPersonalized medicine is an evolving paradigm that aims to tailor therapeutic interventions to individual patient characteristics. With a growing understanding of the genetic, epigenetic, and molecular mechanisms underlying diseases, tailored therapies are becoming more feasible and effective. This review highlights the significant advancements in personalized medicine, focusing specifically on pharmacological strategi Read More
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Comparison of the Characteristics of Circulating Small Extracellular Vesicles Isolated by Ultracentrifugation and a Commercial Kit
Authors: Reza Afrisham, Vida Farrokhi, Roya Moradi and Shaban AlizadehAvailable online: 25 October 2024More LessIntroduction The market offers a wide range of extracellular vesicles (EVs) isolation products, but their lack of standardization is a concern. Therefore, it is important to carefully assess the quality of the EVs obtained using these products. In this study, we compared the EXOCIB kit with the ultracentrifuge method, which is considered the gold standard for small EV isolation. Methods After overnight fasting, small plasma E Read More
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Gluconic Acid Production
Authors: Savas Anastassiadis and Igor G. Morgunov
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