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2000
Volume 20, Issue 3
  • ISSN: 1872-2083
  • E-ISSN: 2212-4012

Abstract

Biosensors are devices that generate signals by interaction of biological elements and analytes, mainly based on their concentration. These are especially composed of enzymes or antibodies. They are associated with a physio-chemical transducer. Their rapid, simple, and real-time detection is of great importance in chemistry, analysis, and drug discovery and development. Phytoconstituents are biologically active compounds mainly synthesized by plants to support their growth and defend against various stresses. Medicinal plants and their products have a vast history of use in traditional medicine, but they are not reliable due to their narrow range and adverse and toxic effects. Moreover, they have vast therapeutic effects on humans, from antibiotics to anti-neoplastic agents. Hence, there is a need for an efficient method to detect and measure these phytoconstituents, and biosensors seem to be the solution. This article provides an overview of various biosensors that can be utilized to identify widely used phytoconstituents, also known as secondary metabolites, such as alkaloids, tannins, flavonoids, terpenoids, cardiac glycosides, and phenolic compounds. The article discusses different types of biosensors, including impedimetric immunosensors, Riboswitch-based biosensors, DNA biosensors, electrochemical biosensors, and others. Furthermore, the potential for patentable innovations in biosensor technologies targeting phytoconstituent detection is also highlighted, emphasizing their growing relevance in both scientific research and commercial applications.

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References

  1. DasA. PanditaD. JainG.K. Role of phytoconstituents in the management of COVID-19.Chem. Biol. Interact.202134110944910.1016/j.cbi.2021.109449 33798507
     [Google Scholar]
  2. SüntarI. Importance of ethnopharmacological studies in drug discovery: Role of medicinal plants.Phytochem. Rev.20201951199120910.1007/s11101‑019‑09629‑9
     [Google Scholar]
  3. VeluG. PalanichamyV. RajanA.P. Phytochemical and pharmacological importance of plant secondary metabolites in modern medicine.Bioorganic Phase in Natural Food: An Overview. RoopanS. MadhumithaG. ChamSpringer201813515610.1007/978‑3‑319‑74210‑6_8
     [Google Scholar]
  4. JainC. KhatanaS. VijayvergiaR. Bioactivity of secondary metabolites of various plants: A review.Int. J. Pharm. Sci. Res.201910249450410.13040/IJPSR.0975‑8232.10(2).494‑04
     [Google Scholar]
  5. RanjhaM.M.A.N. KanwalR. ShafiqueB. A critical review on pulsed electric field: A novel technology for the extraction of phytoconstituents.Molecules20212616489310.3390/molecules26164893 34443475
     [Google Scholar]
  6. HeinrichM. MahJ. AmirkiaV. Alkaloids used as medicines: Structural phytochemistry meets biodiversity - An update and forward look.Molecules2021267183610.3390/molecules26071836 33805869
     [Google Scholar]
  7. SiswinaT. RustamaM.M. SumiarsaD. KurniaD. Phytochemical profiling of Piper crocatum and its antifungal mechanism action as Lanosterol 14 alpha demethylase CYP51 inhibitor: A review.F1000 Res.202211111510.12688/f1000research.125645.3 37151610
     [Google Scholar]
  8. ChungK.T. WongT.Y. WeiC.I. HuangY.W. LinY. Tannins and human health: A review.Crit. Rev. Food Sci. Nutr.199838642146410.1080/10408699891274273 9759559
     [Google Scholar]
  9. ThollD. Biosynthesis and biological functions of terpenoids in plants.Adv. Biochem. Eng. Biotechnol.20151486310610.1007/10_2014_295 25583224
     [Google Scholar]
  10. YiL. MaS. RenD. Phytochemistry and bioactivity of Citrus flavonoids: A focus on antioxidant, anti-inflammatory, anticancer and cardiovascular protection activities.Phytochem. Rev.201716347951110.1007/s11101‑017‑9497‑1
     [Google Scholar]
  11. AliS.A. SinghG. DatusaliaA.K. Potential therapeutic applications of phytoconstituents as immunomodulators: Pre‐clinical and clinical evidences.Phytother. Res.20213573702373110.1002/ptr.7068 33734511
     [Google Scholar]
  12. XueF. LiX. QinL. LiuX. LiC. AdhikariB. Anti-aging properties of phytoconstituents and phyto-nanoemulsions and their application in managing aging-related diseases.Adv. Drug Deliv. Rev.202117611388610.1016/j.addr.2021.113886 34314783
     [Google Scholar]
  13. SaxenaM. SaxenaJ. NemaR. SinghD. GuptaA. Phytochemistry of medicinal plants.J. Pharmacogn. Phytochem.201316168182
     [Google Scholar]
  14. ShuklaA. DubeyS.A. A review: Traditionally used medicinal plants of family arecaceae with phytoconstituents and therapeutic applications.Int. J. Boil. Pharm. Allied Sci.202211125864587710.31032/IJBPAS/2022/11.12.6655
     [Google Scholar]
  15. SinghA.K. RaiS.N. MauryaA. Therapeutic potential of phytoconstituents in management of Alzheimer’s disease.Evid. Based Complement. Alternat. Med.20212021111910.1155/2021/5578574 34211570
     [Google Scholar]
  16. WinkM. Modes of action of herbal medicines and plant secondary metabolites.Medicines (Basel)20152325128610.3390/medicines2030251 28930211
     [Google Scholar]
  17. BejčekJ. JurášekM. SpiwokV. RimpelováS. Quo vadis cardiac glycoside research?Toxins (Basel)202113534410.3390/toxins13050344 34064873
     [Google Scholar]
  18. BealeT.M. TaylorM.S. Synthesis of cardiac glycoside analogs by catalyst-controlled, regioselective glycosylation of digitoxin.Org. Lett.20131561358136110.1021/ol4003042 23465047
     [Google Scholar]
  19. XueR. HanN. YeC. The cytotoxic activities of cardiac glycosides from Streptocaulon juventas and the structure–activity relationships.Fitoterapia20149822823310.1016/j.fitote.2014.08.008 25128424
     [Google Scholar]
  20. LiX. ZhengJ. ChenS. MengF. NingJ. SunS. Oleandrin, a cardiac glycoside, induces immunogenic cell death via the PERK/elF2α/ATF4/CHOP pathway in breast cancer.Cell Death Dis.202112431410.1038/s41419‑021‑03605‑y 33762577
     [Google Scholar]
  21. YangL. ZhouF. ZhuangY. Acetyl-bufalin shows potent efficacy against non-small-cell lung cancer by targeting the CDK9/STAT3 signalling pathway.Br. J. Cancer2021124364565710.1038/s41416‑020‑01135‑6 33122847
     [Google Scholar]
  22. WhayneT.F. Clinical use of digitalis: a state of the art review.Am. J. Cardiovasc. Drugs201818642744010.1007/s40256‑018‑0292‑1 30066080
     [Google Scholar]
  23. FuerstenwerthH. On the differences between ouabain and digitalis glycosides.Am. J. Ther.2014211354210.1097/MJT.0b013e318217a609 21642827
     [Google Scholar]
  24. DeepakD. SrivastavaS. KhareN.K. Cardiac glycosides.Fortschr. Chem. Org. Naturst.1996697115510.1007/978‑3‑7091‑6578‑2_2 8981834
     [Google Scholar]
  25. BotelhoA.F.M. PierezanF. Soto-BlancoB. MeloM.M. A review of cardiac glycosides: Structure, toxicokinetics, clinical signs, diagnosis and antineoplastic potential.Toxicon2019158636810.1016/j.toxicon.2018.11.429 30529380
     [Google Scholar]
  26. Britannica T. of Encyclopaedia. Organ.2023Available from: https://www.britannica.com/science/organ-biology
  27. BhambhaniS. KondhareK.R. GiriA.P. Diversity in chemical structures and biological properties of plant alkaloids.Molecules20212611337410.3390/molecules26113374 34204857
     [Google Scholar]
  28. TakshakS. AgrawalS.B. Defense potential of secondary metabolites in medicinal plants under UV-B stress.J. Photochem. Photobiol. B2019193518810.1016/j.jphotobiol.2019.02.002 30818154
     [Google Scholar]
  29. LiuC. YangS. WangK. Alkaloids from traditional Chinese medicine against hepatocellular carcinoma.Biomed. Pharmacother.201912010954310.1016/j.biopha.2019.109543 31655311
     [Google Scholar]
  30. ElissawyA.M. Soleiman DehkordiE. MehdinezhadN. AshourM.L. PourM.P. Cytotoxic alkaloids derived from marine sponges: A comprehensive review.Biomolecules202111225810.3390/biom11020258 33578987
     [Google Scholar]
  31. DeyP. KunduA. KumarA. Analysis of alkaloids (indole alkaloids, isoquinoline alkaloids, tropane alkaloids).In: Recent Advances in Natural Products Analysis.Elsevier202050556710.1016/B978‑0‑12‑816455‑6.00015‑9
     [Google Scholar]
  32. MathewB. SureshJ.E. MathewG. ParasuramanR. AbdullaN. Plant secondary metabolites - Potent inhibitors of monoamine oxidase isoforms.Cent. Nerv. Syst. Agents Med. Chem.2014146283310.2174/1871524914666140826111930
     [Google Scholar]
  33. AdamskiZ. BlytheL.L. MilellaL. BufoS.A. Biological activities of alkaloids: From toxicology to pharmacology.Toxins (Basel)202012421010.3390/toxins12040210 32224853
     [Google Scholar]
  34. RenM. LotfipourS. Nicotine gateway effects on adolescent substance use.West. J. Emerg. Med.201920569670910.5811/westjem.2019.7.41661 31539325
     [Google Scholar]
  35. BenchikhY. Bachir-BeyM. ChaalalM. YdjeddS. KatiD.E. Extraction of phenolic compounds.In: Green Sustainable Process for Chemical and Environmental Engineering and Science.Elsevier2023329354
     [Google Scholar]
  36. LattanzioV. Phenolic compounds: Introduction.In: Natural Products.Berlin, HeidelbergSpringer201310.1007/978‑3‑642‑22144‑6_57
     [Google Scholar]
  37. HaminiukC.W.I. MacielG.M. Plata-OviedoM.S.V. PeraltaR.M. Phenolic compounds in fruits – An overview.Int. J. Food Sci. Technol.201247102023204410.1111/j.1365‑2621.2012.03067.x
     [Google Scholar]
  38. VuoloM.M. LimaV.S. MarósticaM.R. Chapter 2 - Phenolic compounds: Structure, classification, and antioxidant power.Bioactive Compounds. CamposM.R.S. Woodhead Publishing2019335010.1016/B978‑0‑12‑814774‑0.00002‑5
     [Google Scholar]
  39. RentzschM. WilkensA. WinterhalterP. Non-flavonoid phenolic compounds.In: Wine chemistry and biochemistry.New York, NYSpringer New York200950952710.1007/978‑0‑387‑74118‑5_23
     [Google Scholar]
  40. CliffordM.N. Dietary hydroxybenzoic acid derivatives-nature, occurrence and dietary burden.J. Sci. Food Agric.20008071024103210.1002/(SICI)1097‑0010(20000515)80:7<1024:AID‑JSFA567>3.0.CO;2‑S
     [Google Scholar]
  41. El-SeediH.R. El-SaidA.M.A. KhalifaS.A.M. Biosynthesis, natural sources, dietary intake, pharmacokinetic properties, and biological activities of hydroxycinnamic acids.J. Agric. Food Chem.20126044108771089510.1021/jf301807g 22931195
     [Google Scholar]
  42. TsaoR. Chemistry and biochemistry of dietary polyphenols.Nutrients20102121231124610.3390/nu2121231 22254006
     [Google Scholar]
  43. KumarS. PandeyA.K. Chemistry and biological activities of flavonoids: An overview.Sci World J20132013116275010.1155/2013/162750 24470791
     [Google Scholar]
  44. PancheA.N. DiwanA.D. ChandraS.R. Flavonoids: An overview.J. Nutr. Sci.20165e4710.1017/jns.2016.41 28620474
     [Google Scholar]
  45. SamantaA. DasG. DasS.K. Roles of flavonoids in plants.Carbon201110061235
     [Google Scholar]
  46. CalderaroA. PatanèG.T. TelloneE. The neuroprotective potentiality of flavonoids on Alzheimer’s disease.Int. J. Mol. Sci.202223231483510.3390/ijms232314835 36499159
     [Google Scholar]
  47. HavsteenB.H. The biochemistry and medical significance of the flavonoids.Pharmacol. Ther.2002962-36720210.1016/S0163‑7258(02)00298‑X 12453566
     [Google Scholar]
  48. SiedlerS. StahlhutS.G. MallaS. MauryJ. NevesA.R. Novel biosensors based on flavonoid-responsive transcriptional regulators introduced into Escherichia coli.Metab. Eng.2014212810.1016/j.ymben.2013.10.011 24188962
     [Google Scholar]
  49. RodriguezA StruckoT StahlhutSG Metabolic engineering of yeast for fermentative production of flavonoids.Bioresour Technol2017245(Pt B)16455410.1016/j.biortech.2017.06.043 28634125
     [Google Scholar]
  50. LudwiczukA. Skalicka-WoźniakK. GeorgievM.I. Chapter 11 - Terpenoids.In: Pharmacognosy.Academic Press201723326610.1016/B978‑0‑12‑802104‑0.00011‑1
     [Google Scholar]
  51. DevS. Terpenoids.In: Natural Products of Woody Plants.Berlin, HeidelbergSpringer198969180710.1007/978‑3‑642‑74075‑6_19
     [Google Scholar]
  52. ChengA.X. LouY.G. MaoY.B. LuS. WangL.J. ChenX.Y. Plant terpenoids: Biosynthesis and ecological functions.J. Integr. Plant Biol.200749217918610.1111/j.1744‑7909.2007.00395.x
     [Google Scholar]
  53. MasyitaA. Mustika SariR. Dwi AstutiA. Terpenes and terpenoids as main bioactive compounds of essential oils, their roles in human health and potential application as natural food preservatives.Food Chem. X20221310021710.1016/j.fochx.2022.100217 35498985
     [Google Scholar]
  54. ZwengerS. BasuC. Plant terpenoids: Applications and future potentials.Biotechnol. Mol. Biol. Rev.2008311
     [Google Scholar]
  55. SerranoJ. Puupponen-PimiäR. DauerA. AuraA.M. Saura-CalixtoF. Tannins: Current knowledge of food sources, intake, bioavailability and biological effects.Mol. Nutr. Food Res.200953S2S310S32910.1002/mnfr.200900039 19437486
     [Google Scholar]
  56. SzczurekA. Perspectives on tannins.Biomolecules202111344210.3390/biom11030442 33809775
     [Google Scholar]
  57. PrigioneV. SpinaF. TiginiV. GiovandoS. VareseG.C. Biotransformation of industrial tannins by filamentous fungi.Appl. Microbiol. Biotechnol.201810224103611037510.1007/s00253‑018‑9408‑4 30293196
     [Google Scholar]
  58. TongZ. HeW. FanX. GuoA. Biological function of plant tannin and its application in animal health.Front. Vet. Sci.2022880365710.3389/fvets.2021.803657 35083309
     [Google Scholar]
  59. EngströmM.T. ArvolaJ. NenonenS. Structural features of hydrolyzable tannins determine their ability to form insoluble complexes with bovine serum albumin.J. Agric. Food Chem.201967246798680810.1021/acs.jafc.9b02188 31134805
     [Google Scholar]
  60. RaufA. ImranM. Abu-IzneidT. Proanthocyanidins: A comprehensive review.Biomed. Pharmacother.201911610899910.1016/j.biopha.2019.108999 31146109
     [Google Scholar]
  61. HiroshiH. YoshinobuK. TsutomuH. TakashiY. TakuoO. Antihepatotoxic actions of tannins.J. Ethnopharmacol.1985141192910.1016/0378‑8741(85)90024‑8 4087919
     [Google Scholar]
  62. MarcińczykN. Gromotowicz-PopławskaA. TomczykM. ChabielskaE. Tannins as hemostasis modulators.Front. Pharmacol.20221280689110.3389/fphar.2021.806891 35095516
     [Google Scholar]
  63. RicciA. OlejarK.J. ParpinelloG.P. Antioxidant activity of commercial food grade tannins exemplified in a wine model.Food Addit. Contam. Part A Chem. Anal. Control Expo. Risk Assess.201633121761177410.1080/19440049.2016.1241901 27696959
     [Google Scholar]
  64. AyatiZ. AmiriM.S. RamezaniM. DelshadE. SahebkarA. EmamiS.A. Phytochemistry, traditional uses and pharmacological profile of rose hip: A review.Curr. Pharm. Des.201924354101412410.2174/1381612824666181010151849 30317989
     [Google Scholar]
  65. YalavarthiC. ThiruvengadarajanV.S. A review on identification strategy of phyto constituents present in herbal plants.Int J Res Pharm Sci201342123140
     [Google Scholar]
  66. IngleK.P. DeshmukhA.G. PadoleD.A. DudhareM.S. MoharilM.P. KhelurkarV.C. Phytochemicals: Extraction methods, identification and detection of bioactive compounds from plant extracts.J. Pharmacogn. Phytochem.2017613236
     [Google Scholar]
  67. KatiyarD. Manish, Saxena Pal R, Bansal P, Kumar A, Prakash S. Electrochemical sensors for detection of phytomolecules: A mechanistic approach.Comb. Chem. High Throughput Screen.202427131887189910.2174/0113862073282883231218145941 38279749
     [Google Scholar]
  68. YooE.H. LeeS.Y. Glucose biosensors: An overview of use in clinical practice.Sensors (Basel)20101054558457610.3390/s100504558 22399892
     [Google Scholar]
  69. AbidS.A. Ahmed MuneerA. Al-KadmyI.M.S. Biosensors as a future diagnostic approach for COVID-19.Life Sci.202127311911710.1016/j.lfs.2021.119117 33508293
     [Google Scholar]
  70. MehrotraP. Biosensors and their applications – A review.J. Oral Biol. Craniofac. Res.20166215315910.1016/j.jobcr.2015.12.002 27195214
     [Google Scholar]
  71. ArlettJ.L. MyersE.B. RoukesM.L. Comparative advantages of mechanical biosensors.Nat. Nanotechnol.20116420321510.1038/nnano.2011.44 21441911
     [Google Scholar]
  72. YüceM. KurtH. How to make nanobiosensors: Surface modification and characterisation of nanomaterials for biosensing applications.RSC Advances2017778493864940310.1039/C7RA10479K
     [Google Scholar]
  73. PohankaM. Overview of piezoelectric biosensors, immunosensors and DNA sensors and their applications.Materials (Basel)201811344810.3390/ma11030448 29562700
     [Google Scholar]
  74. KhaterM. de la Escosura-MuñizA. MerkoçiA. Biosensors for plant pathogen detection.Biosens. Bioelectron.201793728610.1016/j.bios.2016.09.091 27818053
     [Google Scholar]
  75. MehrvarM. AbdiM. Recent developments, characteristics, and potential applications of electrochemical biosensors.Anal. Sci.20042081113112610.2116/analsci.20.1113 15352497
     [Google Scholar]
  76. Pashazadeh-PanahiP. HasanzadehM. Digoxin as a glycosylated steroid-like therapeutic drug: Recent advances in the clinical pharmacology and bioassays of pharmaceutical compounds.Biomed. Pharmacother.202012310981310.1016/j.biopha.2020.109813 31924598
     [Google Scholar]
  77. Vale-GonzalezC. PazosM.J. AlfonsoA. VieytesM.R. BotanaL.M. Study of the neuronal effects of ouabain and palytoxin and their binding to Na,] K-ATPases using an optical biosensor.Toxicon200750454155210.1016/j.toxicon.2007.04.024 17548099
     [Google Scholar]
  78. CushR. CroninJ.M. StewartW.J. MauleC.H. MolloyJ. GoddardN.J. The resonant mirror: A novel optical biosensor for direct sensing of biomolecular interactions Part I: Principle of operation and associated instrumentation.Biosens. Bioelectron.199387-834735410.1016/0956‑5663(93)80073‑X
     [Google Scholar]
  79. AmbrinG. KausarH. AhmadA. Designing and construction of genetically encoded FRET-based nanosensor for qualitative analysis of digoxin.J. Biotechnol.202032332233010.1016/j.jbiotec.2020.09.008 32937180
     [Google Scholar]
  80. AhmadiA. ShiraziH. PourbagherN. AkbarzadehA. OmidfarK. An electrochemical immunosensor for digoxin using core–shell gold coated magnetic nanoparticles as labels.Mol. Biol. Rep.20144131659166810.1007/s11033‑013‑3014‑4 24395297
     [Google Scholar]
  81. XiuY. JangS. JonesJ.A. Naringenin‐responsive riboswitch‐based fluorescent biosensor module for Escherichia coli co‐cultures.Biotechnol. Bioeng.2017114102235224410.1002/bit.26340 28543037
     [Google Scholar]
  82. WangR. CressB.F. YangZ. Design and characterization of biosensors for the screening of modular assembled naringenin biosynthetic library in Saccharomyces cerevisiae.ACS Synth. Biol.2019892121213010.1021/acssynbio.9b00212 31433622
     [Google Scholar]
  83. MitchlerM.M. GarciaJ.M. MonteroN.E. WilliamsG.J. Transcription factor-based biosensors: A molecular-guided approach for natural product engineering.Curr. Opin. Biotechnol.20216917218110.1016/j.copbio.2021.01.008 33493842
     [Google Scholar]
  84. MarsafariM. SamizadehH. RabieiB. MehrabiA. KoffasM. XuP. Biotechnological production of flavonoids: An update on plant metabolic engineering, microbial host selection, and genetically encoded biosensors.Biotechnol. J.2020158190043210.1002/biot.201900432 32267085
     [Google Scholar]
  85. NabiabadH.S. AminiM. Fabrication of an impedimetric immunosensor for screening and determination of vincristine in biological samples.J. Anal. Chem.20207581094110110.1134/S1061934820080092
     [Google Scholar]
  86. d’OelsnitzS. NguyenV. AlperH.S. EllingtonA.D. Evolving a generalist biosensor for bicyclic monoterpenes.ACS Synth. Biol.202211126527210.1021/acssynbio.1c00402 34985281
     [Google Scholar]
  87. KimS.K. KimS.H. SubhadraB. A genetically encoded biosensor for monitoring isoprene production in engineered Escherichia coli.ACS Synth. Biol.20187102379239010.1021/acssynbio.8b00164 30261142
     [Google Scholar]
  88. EnsafiA.A. Nasr-EsfahaniP. Heydari-BafrooeiE. RezaeiB. Determination of atropine sulfate using a novel sensitive DNA–biosensor based on its interaction on a modified pencil graphite electrode.Talanta201513114915510.1016/j.talanta.2014.07.082 25281086
     [Google Scholar]
  89. MokhtarzadehA. DolatabadiE.N.J. AbnousK. de la GuardiaM. RamezaniM. Nanomaterial-based cocaine aptasensors.Biosens. Bioelectron.2015689510610.1016/j.bios.2014.12.052 25562736
     [Google Scholar]
  90. d’OelsnitzS. KimW. BurkholderN.T. Using fungible biosensors to evolve improved alkaloid biosyntheses.Nat. Chem. Biol.202218998198910.1038/s41589‑022‑01072‑w 35799063
     [Google Scholar]
  91. TarasovA. StozhkoN. BukharinovaM. KhamzinaE. Biosensors based on phenol oxidases (laccase, tyrosinase, and their mixture) for estimating the total phenolic index in food-related samples.Life (Basel)202313229110.3390/life13020291 36836650
     [Google Scholar]
  92. NavaA.G.S. DelgadoR.J.M. SaldivarP.R. ChapaM.S.O. AssadD.G. Laccase-based biosensors for detection of phenolic compounds.Trends Analyt. Chem.201574214510.1016/j.trac.2015.05.008
     [Google Scholar]
  93. GutésA. CéspedesF. AlegretS. del ValleM. Determination of phenolic compounds by a polyphenol oxidase amperometric biosensor and artificial neural network analysis.Biosens. Bioelectron.20052081668167310.1016/j.bios.2004.07.026 15626626
     [Google Scholar]
  94. SanzJ. de MarcosS. GalbánJ. Autoindicating optical properties of laccase as the base of an optical biosensor film for phenol determination.Anal. Bioanal. Chem.2012404235135910.1007/s00216‑012‑6061‑0 22562544
     [Google Scholar]
  95. GagliardiM. ToriG. AgostiniM. Detection of oenological polyphenols via QCM-D measurements.Nanomaterials (Basel)202212116610.3390/nano12010166 35010116
     [Google Scholar]
  96. Sainz-UrruelaC. Vera-LópezS. San AndrésM.P. Díez-PascualA.M. Graphene-based sensors for the detection of bioactive compounds: A review.Int. J. Mol. Sci.2021227331610.3390/ijms22073316 33804997
     [Google Scholar]
  97. RomaniA. MinunniM. MulinacciN. Comparison among differential pulse voltammetry, amperometric biosensor, and HPLC/DAD analysis for polyphenol determination.J. Agric. Food Chem.20004841197120310.1021/jf990767e 10775372
     [Google Scholar]
  98. GerosaL. SauerU. Regulation and control of metabolic fluxes in microbes.Curr. Opin. Biotechnol.201122456657510.1016/j.copbio.2011.04.016 21600757
     [Google Scholar]
  99. RazaviZ. SoltaniM. SouriM. Pazoki-ToroudiH. CRISPR-driven Biosensors: A new frontier in rapid and accurate disease detection.Crit. Rev. Anal. Chem.202412510.1080/10408347.2024.2400267 39288095
     [Google Scholar]
  100. BlaeserA. Evolution of biofabrication and 3D-bioprinting technologies - From market pull to technology push.Automatisierungstechnik202472764565610.1515/auto‑2024‑0070
     [Google Scholar]
  101. PiroozmandF. MohammadipanahF. FaridbodF. Emerging biosensors in detection of natural products.Synth. Syst. Biotechnol.20205429330310.1016/j.synbio.2020.08.002 32954023
     [Google Scholar]
  102. JumperJ. EvansR. PritzelA. Highly accurate protein structure prediction with AlphaFold.Nature2021596787358358910.1038/s41586‑021‑03819‑2 34265844
     [Google Scholar]
  103. Yang,C-H Liu,X Pseudomonas strains and their metabolites to control plant diseases.Patent EP4225892A12023
     [Google Scholar]
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Integrating Biosensors in Phytochemical Research: Challenges and Breakthroughs
Recent Pat. Biotechnol. 20, 355 (2026); https://doi.org/10.2174/0118722083381223250612181959
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  • Article Type:     Review Article
Keyword(s): alkaloids; anti-neoplastic; biosensors; flavonoids; metabolites; Phytoconstituents; Riboswitch-based biosensors

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