Current Bioactive Compounds - Current Issue
Volume 21, Issue 7, 2025
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Network Pharmacology Analysis Reveals Multi-target Interactions of Phytochemicals in Cardiospermum halicacabum and their Potential in Breast Cancer Therapy
Authors: Dhivya Shanmugarajan, Charles David, Arpana Parihar, Pallavi Kulkarni, Neha Arya and Raju KhanAimsThis present study aims to probe the interrelationships between phytochemical components and drug targets in Cardiospermum halicacabum.BackgroundIndian traditional medicine, often called Ayurveda, has a rich history of using medicinal plants for various health remedies and treatments. Network pharmacology plays a significant role in understanding the complex interactions between bioactive compound Read More
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Pharmacological Benefits of Cinnamaldehyde: A Comprehensive Insight
Authors: Aagaz Ali, Sayed Mohammad Ismayel, Mohd Samama, Amit Kumar and Payal GuptaTo provide a comprehensive, detailed review of the pharmacological benefits of cinnamaldehyde (CA) and its derivatives. Cinnamon is one such medicinally important spice that finds space in all Indian kitchens due to its myriad health benefits. This review aims to compile the scientific literature and provide a comprehensive analysis of pharmacological properties and cellular signalling pathways inhibited by CA. For colle Read More
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Guava in Dentistry: A Potent Transition from Traditional to Modern Medicine in Oral Health
Psidium guajava or guava is a plant that contains a variety of bioactive compounds that have been used to treat oral and dental issues. The plant is unique and traditional, with a wide range of therapeutic uses. Guava's healing and medicinal effects have been reported through clinical trials, laboratory studies, and surveys. Over 3.5 billion people worldwide suffer from oral disorders, such as dental caries, periodontal disease, Read More
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Biological Evaluation of Bioactive Compounds of Selaginella plana in Treating Diabetic Neuropathy
Authors: Neeru Singh, Lubhan Singh, Sokindra Kumar and Rupesh Kumar PandeyIntroductionThe study is aimed to assess the plant bioactive compounds of Selaginella plana in treating diabetic neuropathy. The plant components were assessed using ethanol as the solvent.MethodsA phytochemical screening was conducted to ascertain the existence of secondary metabolites in the plant extracts. The efficacy of plant extract against neuropathic pain was determined using plantar test and Von Frey filament sti Read More
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Unlocking the Therapeutic Potential of Medicinal Hemp: Insights into Pharmacokinetics and Metabolism of Cannabinoids
Authors: Syed Sabir Hussain Shah, Saba Latif and Rahmatullah QureshiMedicinal hemp or Cannabis (Cannabis sativa L.) is one of the earliest herbs widely used in traditional medicine by human beings for millions of years. This species was originally thought to be endemic to Asian countries but has now grown worldwide. It is a dioecious and annual plant that belongs to the Cannabaceae family. It has a long history of cultivation for food, intoxicants, hemp medicine, rope, paper, fiber, and oil ex Read More
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Current Bioactive Compounds in the Treatment of Alzheimer's Disease
Authors: Parul Sharma, Rishi Pal, Anuj Kumar Sharma, Abhishek Kumar and Vrish Dhwaj AshwlayanWorldwide, more than 44 million individuals are living with Alzheimer's disease (AD), making it the most common type of dementia. Because neuroinflammation is so important in the development of AD, anti-inflammatory tactics may be a promising avenue for treatment. Searches were conducted in Scopus, the Web of Science, and PubMed using the following keywords: phytoconstituents, AD, traditional medicine, and Ch Read More
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Marine Drugs for Topical Nanoformulation and Cosmeceutical Applications
Authors: Anjali Sharma, Abhishek Singh, Nimisha Srivastava and Deblina DanMarine sources, such as phytoplankton and zooplankton from seas or oceans that correspond to various marine ecosystems, are the sources of marine pharmaceuticals. These medications have been utilized as active ingredients in cosmeceutical formulas to treat a range of skin conditions. Cosmeceuticals, or cosmetic products with an active pharmaceutical ingredient that imparts therapeutic efficacy or has benefits similar Read More
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Neurobehavioural Deficits, Atherogenic Risk, and Oxido-inflammatory Response in Mice Fed with Combined Sodium Benzoate and Monosodium Glutamate Supplementation in Normal and High-fat Diets
Introduction and BackgroundThe overuse of food additives and preservatives has become a source of concern globally due to the inherent risks associated with them. This study evaluated neurobehavioral performance, atherogenic risk, and oxido-inflammatory response in mice fed with normal and high-fat diets supplemented with combined sodium benzoate (SB) and monosodium glutamate (MSG).Materials and Methods Read More
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1,2,3-Triazole Linked 7-Chloroquinoline Hybrids: A Promising Pharmacophore for Biological Applications
Authors: Garima Chand, Penny Joshi, Deepa Kholia, Rini Joshi, Amrita Kumari and Santosh K. UpadhyayHeterocyclic compounds are fundamental in natural products and pharmaceuticals. The triazole nucleus, in particular, is a versatile structure present in numerous bioactive molecules. 7-chloroquinoline is historically significant for its antimalarial properties and exhibits a broad spectrum of biological activities, including antiviral, anticancer, antibacterial, and anti-inflammatory effects. This review aimed to compile and discus Read More
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Physical and Functional Properties of Poly (Lactic Acid)/Paprika Oleoresin Films for Food Packaging Application
BackgroundPaprika oleoresin is a compound extracted from paprika, with functional properties, mainly due to its fatty acid composition and carotenoid profile. The effect of these compounds on PLA composite films has not been investigated.ObjectiveThe objective of this study is to evaluate the effect of paprika oleoresin at different concentrations on the surface color, UV barrier, mechanical barrier, water vapor bar Read More
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Antioxidant and Anti-microbial Activities of Astragalus rhodosemius Boiss. & Hausskn. Extracts
BackgroundOne of the Astragalus (Leguminosae) species with remarkable pharmacological and biological properties is Astragalus rhodosemius, which has been utilized in traditional medicine. Very little study has been conducted on this species thus far. The purpose of this study was to examine the anti-microbial and antioxidant properties of two distinct extracts of Astragalus rhodosemius aerial parts (n-butanol and eth Read More
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Hepatoprotective Effect of Callicarpa lanata (L.) against Antituberculosis Treatment-induced Acute Hepatotoxicity
BackgroundHepatotoxicity is a major complication of antitubercular therapy (ATT). Herbal remedies might alleviate ATT-induced hepatotoxicity owing to a wide range of bioactive phytoconstituents.ObjectivesThe present study evaluated the hepatoprotective effects of Callicarpa lanata (L.) leaves against ATT.MethodsThe ethanolic extract of C. lanata (L.) leaves (EECL) was prepared, and rutin was analyzed in the extract usin Read More
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Volumes & issues
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Volume 21 (2025)
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Volume 20 (2024)
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Volume 19 (2023)
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Volume 18 (2022)
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Volume 17 (2021)
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Volume 16 (2020)
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Volume 15 (2019)
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Volume 14 (2018)
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Volume 13 (2017)
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Volume 12 (2016)
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Volume 11 (2015)
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Volume 10 (2014)
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Volume 9 (2013)
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Volume 8 (2012)
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Volume 7 (2011)
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Volume 6 (2010)
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Volume 5 (2009)
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Volume 4 (2008)
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Volume 3 (2007)
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Volume 2 (2006)
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Volume 1 (2005)
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Podophyllotoxin: Current Perspectives
Authors: Ying Qian Liu, Liu Yang and Xuan Tian
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