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2000
Volume 5, Issue 1
  • ISSN: 1573-4072
  • E-ISSN: 1875-6646

Abstract

This review will focus on the ability of the 2-aminoimidazole to occupy a unique subset of chemical space which makes it an ideal pharmacophore for the development of small molecule collections for discovery based research. These observations rely both on the use of 2-aminoimidazoles as building blocks in medicinal chemistry as well as the recent discovery of alkaloids from sponges of the genus Leucetta which exhibit a diverse range of biological activities around a relatively limited structural core. The preparation of these compounds will also be highlighted.

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/content/journals/cbc/10.2174/157340709787580892
2009-03-01
2024-12-11
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