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2000
Volume 21, Issue 10
  • ISSN: 1573-4072
  • E-ISSN: 1875-6646

Abstract

The family Lamiaceae includes the genus which is widely cultivated throughout the Mediterranean region, including France, Spain, and Italy. The plant forms dense clumps that are roughly 40-60 cm tall. The reference genome for “Jingxun 2,” an excellent cultivar of () was developed by a research team in China. which contains tannins, phytosterols, coumarins, herniarins, ursolic acid, sugars, valeric acid, glycolic acid, coumaric acid, anthocyanins, minerals, and essential oils. oil can also help with many kinds of health problems because it has many bioactive ingredients, such as linalool, lavandulol, anthocyanins, geraniol, ursolic acids, linalyl acetate, valeric acid, 1,8-cineole, borneol, lavandulyl acetate, terpinen-4-ol, camphor, phytosterols, coumaric acid, and glycolic acid. The genus exhibits various biological activities, including antioxidants, antiparasitic, and neuroprotective properties. Recent studies have demonstrated the numerous biological activities of but we still need to develop new medications that harness the components of this plant to treat a variety of illnesses. This study covers various recent advancements in the use of and its phytochemicals by using various search engines, including Scopus, PubMed, Google Scholar, and Web of Science.

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References

  1. BenaliT. LemhadriA. HarboulK. ChtibiH. KhabbachA. JadoualiS.M. Quesada-RomeroL. LouahliaS. HammaniK. GhalebA. LeeL.H. BouyahyaA. RusuM.E. AkhazzaneM. Chemical profiling and biological properties of essential oils of Lavandula stoechas L. Collected from three moroccan sites: In vitro and in silico investigations.Plants2023126141310.3390/plants12061413 36987101
     [Google Scholar]
  2. BatihaG.E.S. TeiboJ.O. WasefL. ShaheenH.M. AkomolafeA.P. TeiboT.K.A. Al-kuraishyH.M. Al-GarbeebA.I. AlexiouA. PapadakisM. A review of the bioactive components and pharmacological properties of Lavandula species.Naunyn Schmiedebergs Arch. Pharmacol.2023396587790010.1007/s00210‑023‑02392‑x 36773055
     [Google Scholar]
  3. CavanaghH.M. WilkinsonJ.M. Lavender essential oil: A review.Austr. Infect. Control20051013537
     [Google Scholar]
  4. PrusinowskaR. ŚmigielskiK.B. Composition, biological properties and therapeutic effects of Lavender L). A review.Herba Pol.2014602566610.2478/hepo‑2014‑0010
     [Google Scholar]
  5. MhmoodZ.F. HashimS.S. AhmedD.M. Copyright© 2020 by academic publishing house researcher sro published in the slovak republic.Russ. J. Biol. Res.2020711420
     [Google Scholar]
  6. GlinkaR. GlinkaM. Cosmetic recipe with elements of cosmetology.Lodz, PolandMA Publishind20087073
     [Google Scholar]
  7. PokajewiczK. Czarniecka-WieraM. KrajewskaA. MaciejczykE. WieczorekP.P. Lavandula intermedia - A bastard Lavender or a plant of many values? Part ii. Biological activities and applications of lavandin.Molecules2023287298610.3390/molecules28072986 37049749
     [Google Scholar]
  8. ElisabetskyE. MarschnerJ. Onofre SouzaD. Effects of linalool on glutamatergic system in the rat cerebral cortex.Neurochem. Res.199520446146510.1007/BF00973103 7651584
     [Google Scholar]
  9. Lis-BalchinM. HartS. Studies on the mode of action of the essential oil of lavender Lavandula angustifolia P. Miller).Phytother. Res.199913654054210.1002/(SICI)1099‑1573(199909)13:6<540::AID‑PTR523>3.0.CO;2‑I 10479772
     [Google Scholar]
  10. RenZ. GouldM.N. Inhibition of ubiquinone and cholesterol synthesis by the monoterpene perillyl alcohol.Cancer Lett.1994762-318519010.1016/0304‑3835(94)90396‑4 8149348
     [Google Scholar]
  11. MillsJ.J. ChariR.S. BoyerI.J. GouldM.N. JirtleR.L. Induction of apoptosis in liver tumors by the monoterpene perillyl alcohol.Cancer Res.1995555979983 7867007
     [Google Scholar]
  12. HaagJ.D. GouldM.N. Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene.Cancer Chemother. Pharmacol.199434647748310.1007/BF00685658 7923558
     [Google Scholar]
  13. LantryL.E. ZhangZ. GaoF. CristK.A. WangY. KelloffG.J. LubetR.A. YouM. Chemopreventive effect of perillyl alcohol on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced tumorigenesis in (C3H/HeJ X A/J)F1 mouse lung.J. Cell. Biochem.199767S27202510.1002/(SICI)1097‑4644(1997)27+<20:AID‑JCB6>3.0.CO;2‑3
     [Google Scholar]
  14. CleggR.J. MiddletonB. BellG.D. WhiteD.A. The mechanism of cyclic monoterpene inhibition of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase in vivo in the rat.J. Biol. Chem.198225752294229910.1016/S0021‑9258(18)34920‑2 7061423
     [Google Scholar]
  15. HohmannJ. ZupkóI. RédeiD. CsányiM. FalkayG. MáthéI. JanicsákG. Protective effects of the aerial parts of Salvia officinalis, Melissa Officinalis and Lavandula angustifolia and their constituents against enzyme-dependent and enzyme-independent lipid peroxidation.Planta Med.199965657657810.1055/s‑2006‑960830 10532875
     [Google Scholar]
  16. PerrucciS. CioniP.L. FlaminiG. MorelliI. MacchioniG. Acaricidal agents of natural origin against Psoroptes cuniculi.Parassitologia1994363269271 7637996
     [Google Scholar]
  17. AkhondzadehS. KashaniL. FotouhiA. JarvandiS. MobaseriM. MoinM. KhaniM. JamshidiA.H. BaghalianK. TaghizadehM. Comparison of Lavandula angustifolia Mill. tincture and imipramine in the treatment of mild to moderate depression: A double-blind, randomized trial.Prog. Neuropsychopharmacol. Biol. Psychiatry200327112312710.1016/S0278‑5846(02)00342‑1 12551734
     [Google Scholar]
  18. El HachlafiN. BenkhairaN. Al-MijalliS.H. MrabtiH.N. AbdnimR. AbdallahE.M. JeddiM. BnouhamM. LeeL.H. ArdiantoC. MingL.C. BouyahyaA. Fikri-BenbrahimK. Phytochemical analysis and evaluation of antimicrobial, antioxidant, and antidiabetic activities of essential oils from Moroccan medicinal plants: Mentha suaveolens, Lavandula stoechas, and Ammi visnaga.Biomed. Pharmacother.202316411493710.1016/j.biopha.2023.114937 37267633
     [Google Scholar]
  19. HanamanthagoudaM.S. KakkalameliS.B. NaikP.M. NagellaP. SeetharamareddyH.R. MurthyH.N. Essential oils of Lavandula bipinnata and their antimicrobial activities.Food Chem.2010118383683910.1016/j.foodchem.2009.05.032
     [Google Scholar]
  20. LinC.W. YuC.W. WuS.C. YihK.H. DPPH free-radical scavenging activity, total phenolic contents and chemical composition analysis of forty-two kinds of essential oils.Yao Wu Shi Pin Fen Xi20091759
     [Google Scholar]
  21. BuchbauerG. JirovetzL. JägerW. DietrichH. PlankC. Aromatherapy: evidence for sedative effects of the essential oil of lavender after inhalation.Z. Naturforsch. C J. Biosci.19914611-121067107210.1515/znc‑1991‑11‑1223 1817516
     [Google Scholar]
  22. HayI.C. JamiesonM. OrmerodA.D. Randomized trial of aromatherapy. Successful treatment for Alopecia areata.Arch. Dermatol.1998134111349135210.1001/archderm.134.11.1349 9828867
     [Google Scholar]
  23. HudsonR. Use of Lavender in a long-term elderly ward.Nurs. Times199591112
     [Google Scholar]
  24. DunnC. SleepJ. CollettD. Sensing an improvement: An experimental study to evaluate the use of aromatherapy, massage and periods of rest in an intensive care unit.J. Adv. Nurs.1995211344010.1046/j.1365‑2648.1995.21010034.x 7897075
     [Google Scholar]
  25. JeddiM. El HachlafiN. El FadiliM. BenkhairaN. Al-MijalliS.H. KandsiF. AbdallahE.M. OuaritiniZ.B. BouyahyaA. LeeL-H. ZenginG. MrabtiH.N. Fikri-BenbrahimK. Antimicrobial, antioxidant, α-amylase and α-glucosidase inhibitory activities of a chemically characterized essential oil from Lavandula angustifolia Mill.: In vitro and in silico investigations.Biochem. Syst. Ecol.202311110473110.1016/j.bse.2023.104731
     [Google Scholar]
  26. BaraaA.M. Review on the medicinal properties of some aromatic hydrosols.Zeugma Biological Science202121119
     [Google Scholar]
  27. El AbdaliY. AgourA. AllaliA. BourhiaM. El MoussaouiA. EloutassiN. SalamatullahA.M. AlzahraniA. OuahmaneL. Aboul-SoudM.A.M. GiesyJ.P. BouiaA. Lavandula dentata L.: Phytochemical analysis, antioxidant, antifungal and insecticidal activities of its essential oil.Plants202211331110.3390/plants11030311 35161292
     [Google Scholar]
  28. Colceru-MihulS. ArmatuA. DraghiciE. NitaS. Studies concerning the relationship between essential elements content and myorelaxant effect of three vegetal selective fractions.Rom. Biotechnol. Lett.200914647924797
     [Google Scholar]
  29. AdnanM. HussainJ. ShahM.T. ShinwariZ.K. UllahF. BahaderA. KhanN. KhanA.L. WatanabeT. Proximate and nutrient composition of medicinal plants of humid and sub-humid regions in North-west Pakistan.J. Med. Plants Res.201044339345
     [Google Scholar]
  30. HabánM. Korczyk-SzabóJ. ČertekováS. RažnáK. Lavandula species, their bioactive phytochemicals, and their biosynthetic regulation.Int. J. Mol. Sci.20232410883110.3390/ijms24108831 37240177
     [Google Scholar]
  31. AprotosoaieA.C. GilleE. TrifanA. LucaV.S. MironA. Essential oils of Lavandula genus: A systematic review of their chemistry.Phytochem. Rev.201716476179910.1007/s11101‑017‑9517‑1
     [Google Scholar]
  32. RamchounM. HarnafiH. AlemC. BenleyM. ElrhaffariL. AmraniS. Study on antioxidant and hypolipidemic effect of polyphenol rich extract from Thymus vulgaris and Lavandula multifida.Pharmacognosy Res.200913106112
     [Google Scholar]
  33. ElmakaouiA. BouraisI. OubihiA. NassifA. BezhinarT. ShariatiM.A. BlinovA.V. HlebaL. HajjajiS.E. Chemical composition and antibacterial activity of essential oil of Lavandula multifida.J. Microbiol. Biotechnol. Food Sci.2022116e755910.55251/jmbfs.7559
     [Google Scholar]
  34. HaddouM. ElbouzidiA. TaibiM. BaraichA. LoukiliE.H. BellaouchiR. SaalaouiE. AsehraouA. SalamatullahA.M. BourhiaM. NafidiH.A. AddiM. GuerroujB.E. ChaabaneK. Exploring the multifaceted bioactivities of Lavandula pinnata L. essential oil: Promising pharmacological activities.Front Chem.202412138373110.3389/fchem.2024.1383731 38660570
     [Google Scholar]
  35. HéralB. StierlinÉ. FernandezX. MichelT. Phytochemicals from the genus Lavandula: A review.Phytochem. Rev.202120475177110.1007/s11101‑020‑09719‑z
     [Google Scholar]
  36. RamchounM. HarnafiH. AlemC. BenlysM. ElrhaffariL. AmraniS. Study on antioxidant and hypolipidemic effects of polyphenol rich extract from Thymus vulgaris and Lavandula multifida.Pharmacognosy Res.200913106112
     [Google Scholar]
  37. SalehiB. MnayerD. ÖzçelikB. AltinG. KasapoğluK.N. Daskaya-DikmenC. Sharifi-RadM. SelamogluZ. AcharyaK. SenS. MatthewsK.R. Tsouh FokouP.V. SharopovF. SetzerW.N. MartorelloM. Sharifi-RadJ. Plants of the genus lavandula.Pharmacy2018131013851402
     [Google Scholar]
  38. GuittonY. NicolèF. JullienF. CaissardJ.C. Saint-MarcouxD. LegendreL. PasquierB. MojaS. A comparative study of terpene composition in different clades of the genus Lavandula.Bot. Lett.20181653-449450510.1080/23818107.2018.1500305
     [Google Scholar]
  39. RathoreS. KumarR. Essential oil content and compositional variability of Lavandula species cultivated in the mid hill conditions of the western himalaya.Molecules20222711339110.3390/molecules27113391 35684332
     [Google Scholar]
  40. PrusinowskaR. ŚmigielskiK.B. Composition, biological properties and therapeutic effects of lavender (Lavandula angustifolia L). A review.Herba Pol.2014602566610.2478/hepo‑2014‑0010
     [Google Scholar]
  41. LawrenceB.M. Progress in essential oils.Perfum. Flavor.2011365258
     [Google Scholar]
  42. ŚmigielskiK. PrusinowskaR. RajA. SikoraM. WoliñskaK. GruskaR. Effect of drying on the composition of essential oil from Lavandula angustifolia.J. Essent. Oil-Bear. Plants201114553254210.1080/0972060X.2011.10643970
     [Google Scholar]
  43. Rajeswara RaoB.R. KaulP.N. BhattacharyaA.K. RajputD.K. SyamasundarK.V. RameshS. Comparative chemical composition of steam-distilled and water-soluble essential oils of South American marigold (Tagetes minuta L.).J. Essent. Oil Res.200618662262610.1080/10412905.2006.9699184
     [Google Scholar]
  44. ŚmigielskiK.B. PrusinowskaR. KrosowiakK. SikoraM. Comparison of qualitative and quantitative chemical composition of hydrolate and essential oils of lavender (Lavandula angustifolia).J. Essent. Oil Res.201325429129910.1080/10412905.2013.775080
     [Google Scholar]
  45. WellsR. TruongF. AdalA. M. SarkerL. S. MahmoudS. S. Lavandula essential oils: A current review of applications in medicinal, food, and cosmetic industries of Lavender.Nat. Prod. Commun.201813101934578X1801301038
     [Google Scholar]
  46. CaputoL. SouzaL. AlloisioS. CornaraL. De FeoV. Coriandrum sativum and Lavandula angustifolia essential oils: Chemical composition and activity on central nervous system.Int. J. Mol. Sci.20161712199910.3390/ijms17121999 27916876
     [Google Scholar]
  47. Alaoui-IsmaïliO. Vernet-MauryE. DittmarA. DelhommeG. ChanelJ. Odor hedonics: Connection with emotional response estimated by autonomic parameters.Chem. Senses199722323724810.1093/chemse/22.3.237 9218136
     [Google Scholar]
  48. SiurinS.A. Effects of essential oil on lipid peroxidation and lipid metabolism in patients with chronic bronchitis.Klin. Med.199775104345 9490339
     [Google Scholar]
  49. DafereraD.J. ZiogasB.N. PolissiouM.G. GC-MS analysis of essential oils from some Greek aromatic plants and their fungitoxicity on Penicillium digitatum.J. Agric. Food Chem.20004862576258110.1021/jf990835x 10888587
     [Google Scholar]
  50. InouyeS. WatanabeM. NishiyamaY. TakeoK. AkaoM. YamaguchiH. Antisporulating and respiration‐inhibitory effects of essential oils on filamentous fungi.Mycoses1998419-1040341010.1111/j.1439‑0507.1998.tb00361.x 9916464
     [Google Scholar]
  51. UpcroftP. UpcroftJ.A. Drug targets and mechanisms of resistance in the anaerobic protozoa.Clin. Microbiol. Rev.200114115016410.1128/CMR.14.1.150‑164.2001 11148007
     [Google Scholar]
  52. Hamad Al-MijalliS. Determination of volatile compounds of Mentha piperita and Lavandula multifida andinvestigation of their antibacterial, antioxidant, and antidiabetic properties.Evid. Based Complement. Alternat. Med.20229306251 35747375
     [Google Scholar]
  53. MazzantiG. LuM. SalvatoreG. Spasmolytic action of the essential oil from Hyssopus officinalis L. var. decumbens and its major components.Phytother. Res.199812S1S92S9410.1002/(SICI)1099‑1573(1998)12:1+<S92:AID‑PTR261>3.0.CO;2‑9
     [Google Scholar]
  54. KaranN.B. Influence of lavender oil inhalation on vital signs and anxiety: A randomized clinical trial.Physiol. Behav.201921111267610.1016/j.physbeh.2019.112676 31505191
     [Google Scholar]
  55. CavanaghH.M.A. WilkinsonJ.M. Biological activities of Lavender essential oil.Phytother. Res.200216430130810.1002/ptr.1103 12112282
     [Google Scholar]
  56. HuiL. HeL. HuanL. Chemical composition of Lavender essential oil and its antioxidant activity and inhibition against rhinitis-related bacteria.Afr. J. Microbiol. Res.201044309313
     [Google Scholar]
  57. HussainA.I. AnwarF. IqbalT. BhattiI.A. Antioxidant attributes of four Lamiaceae essential oils.Pak. J. Bot.201143213151321
     [Google Scholar]
  58. KritsidimaM. NewtonT. AsimakopoulouK. The effects of lavender scent on dental patient anxiety levels: A cluster randomised‐controlled trial.Community Dent. Oral Epidemiol.2010381838710.1111/j.1600‑0528.2009.00511.x 19968674
     [Google Scholar]
  59. SkoglundL.A. JorkjendL. Postoperative pain experience after gingivectomies using different combinations of local anaesthetic agents and periodontal dressings.J. Clin. Periodontol.199118320420910.1111/j.1600‑051X.1991.tb01135.x 2061421
     [Google Scholar]
  60. GilaniA.H. AzizN. KhanM.A. ShaheenF. JabeenQ. SiddiquiB.S. HerzigJ.W. Ethnopharmacological evaluation of the anticonvulsant, sedative and antispasmodic activities of Lavandula stoechas L.J. Ethnopharmacol.2000711-216116710.1016/S0378‑8741(99)00198‑1 10904159
     [Google Scholar]
  61. ArantesS. CandeiasF. LopesO. LimaM. PereiraM. TinocoT. Cruz-MoraisJ. MartinsM. Pharmacological and toxicological studies of essential oil of Lavandula stoechas subsp. luisieri.Planta Med.201682141266127310.1055/s‑0042‑104418 27124241
     [Google Scholar]
  62. ZuzarteM. GonçalvesM.J. CavaleiroC. CruzM.T. BenzartiA. MarongiuB. MaxiaA. PirasA. SalgueiroL. Antifungal and anti-inflammatory potential of Lavandula stoechas and Thymus herba-barona essential oils.Ind. Crops Prod.2013449710310.1016/j.indcrop.2012.11.002
     [Google Scholar]
  63. MirajS. Lavandula stoechas L.: A systematic review of medicinal and molecular perspectives.Pharm. Lett.201656170179
     [Google Scholar]
  64. BenabdelkaderT. ZitouniA. GuittonY. JullienF. MaitreD. CasabiancaH. LegendreL. KameliA. Essential oils from wild populations of Algerian Lavandula stoechas L.: Composition, chemical variability, and in vitro biological properties.Chem. Biodivers.20118593795310.1002/cbdv.201000301 21560242
     [Google Scholar]
  65. SaririR. SeifzadehS. SajediR.H. Anti-tyrosinase and antioxidant activity of Lavandula sp. extracts.Pharmacology20093319326
     [Google Scholar]
  66. GörenA.C. TopçuG. BilselG. BilselM. AydoğmusçZ. PezzutoJ.M. The chemical constituents and biological activity of essential oil of Lavandula stoechas ssp. stoechas.Z. Naturforsch. C J. Biosci.2002579-1079780010.1515/znc‑2002‑9‑1007 12440714
     [Google Scholar]
  67. SelmiS. JallouliM. GharbiN. MarzoukiL. Hepatoprotective and renoprotective effects of Lavender (Lavandula stoechas L.) essential oils against malathion-induced oxidative stress in young male mice.J. Med. Food201518101103111110.1089/jmf.2014.0130 25835641
     [Google Scholar]
  68. TahraouiA. El-HilalyJ. IsrailiZ.H. LyoussiB. Ethnopharmacological survey of plants used in the traditional treatment of hypertension and diabetes in south-eastern Morocco (Errachidia province).J. Ethnopharmacol.2007110110511710.1016/j.jep.2006.09.011 17052873
     [Google Scholar]
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Lavandula Species as a Bioactive Phytomolecules and Medicinal Properties: A Review
Curr. Bioact. Compd. 21, E15734072340415 (2025); https://doi.org/10.2174/0115734072340415250127055229
/content/journals/cbc/10.2174/0115734072340415250127055229
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  • Article Type:     Review Article
Keyword(s): anthocyanins; antioxidant; aromatherapy; coumaric acid; Lavandula; ursolic acids

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