Pharmaceutical Nanotechnology - Volume 13, Issue 3, 2025
Volume 13, Issue 3, 2025
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An Overview of the Anticancer Potential of Silver Nanostructures against Cervical Cancer
Authors: Adarsh Kumar, Dhruv Varshney, Shivam Kumar and Sarmistha SahaWomen are impacted by the extremely common cancer known as cervical cancer worldwide. Although preventive vaccines for cervical cancer are successful, treatment of cervical cancer is far less satisfactory because of multidrug resistance and side effects. There is an increasing need for alternative treatment modalities due to the rather aggressive and non-specific nature of conventional chemotherapeutics. With the adv Read More
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Emerging Nanotechnological Applications in Preserving and Improving the Shelf Life of Food
Authors: Rashmi Saini, Neha Paserkar, Anand Varma, Dhaval K. Acharya, Vijay Upadhye, Dinesh Pathak and Ashish WarghaneThe ever-growing demand for safe and nutritious food has activated the scrutinization of innovative approaches to enhance food preservation and extended shelf life. Nanotechnology has progressed by making a significant contribution to the food industry at the nanoscale level and appeared as a promising avenue for these challenges. Various nanomaterials have been employed to preserve and extend the shelf life of a variet Read More
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Smart Materials Design for Antibacterial Application
In response to the escalating issue of antibiotic-resistant bacteria adhering to and thriving on medical equipment, scientists are pioneering innovative “intelligent” materials and coatings. These advancements entail the targeted release of antimicrobial substances, specifically activated when bacteria are detected. The next section discusses three revolutionary substances: hydrogels, nanoparticles, and thin films. Further Read More
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The Know-how of Polymeric Nanocarrier Based Vaginal Drug Delivery System: Pitfalls, Challenges and Trends
Authors: Pranita Kanojiya, Rita Wadetwar, Megha Karemore and Satyendra PrasadObjectivesGynecological health is a global concern, and thus, the formulator researcher strives to improve the quality of life through innovative feminine pharmaceutical formulations. Vaginal delivery appears to be one of the vital strategies for local and systemic action of the therapeutically active agent. The rich vascular network, mucosal permeability, bypass of hepatic first-pass effect, and low enzymatic activity are the ex Read More
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Eco-friendly Synthesis of Azadirachta indica-based Metallic Nanoparticles for Biomedical Application & Future Prospective
Authors: Puja Kumari, Laxmi Devi, Renu Kadian, Aafrin Waziri and Md Sabir AlamThe process of producing the metallic nanoparticles (MNPs) in a sustainable and environment-friendly process is very desirable due to environmental hazards posed by climatic changes. Biomedical one of the fields classified under nanoscience, nanoparticles have a potential synthetic application, which makes it a vast area of research. These particles can be prepared using chemical, physical, and biological m Read More
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Innovations in Skin Cancer Nanotechnology: A Comprehensive Review
Authors: Sonia Singh and Mayuri VarshneySkin cancer is the most common type of cancer among white people, according to the World Health Organisation. The incidence of melanoma and non-melanoma skin cancers has increased to epidemic levels, making them the most widespread type of skin cancer. Melanoma is a very aggressive form of cancer, characterized by limited treatment choices due to multidrug resistance and an extremely low probability of p Read More
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Role of Nanomedicine for Targeted Drug Delivery in Livestock: Future Prospective
Authors: Neeti Hooda, Aarti Ahlawat, Puja Kumari, Md. Sabir Alam and Jamilur R. AnsariNanotechnology has advanced significantly in recent years and is currently used in a wide range of sectors. Only a handful of the many diverse issues covered by nanotechnology include nanoscale gadgets, nanomaterials, nanoparticles, and nanomedicines. Its performance in treating a range of grave conditions, such as cancer, early detection of infections, analysis, bio-imaging, and bio sensing, suggests that it is highly Read More
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Formulation Strategy and An Overview of Nano-Structured Lipid Carrier-Based Topical Gel as a Novel Drug Delivery System
Authors: Ujjwal Kumar Biswas and Anindya BoseNano-Structured Lipid Carriers (NLCs) are improved Solid Lipid Nanoparticles (SLNs) that recover the permanency and capacity of drug payload. There are 3 different types of NLCs which have been anticipated. The aforementioned Lipid Nano Particles (LNPs) possess possible tenders in drug delivery systems, cosmeceuticals, clinical research and many others. Here, we highlight the structure, ingredients, different manufacturi Read More
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Recent Advances in the Preparation, Properties, and Applications of Solid Lipid Nanoparticles in Drug Delivery
Authors: Ujjwal Kumar Biswas, Anindya Bose and Ankita ParmanikSolid lipid nanoparticles (SLNs) are one of the extensively utilized nanocarriers in the pharmaceutical field due to their biocompatibility and biodegradability. These features of the carrier system have fuelled its use as the drug delivery system since the last three decades. This review presents different SLN preparation techniques, such as high shear homogenization, hot homogenization, cold homogenization, microem Read More
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Envisioning the Future: Nanomicelles Revolutionizing Ocular Drug Delivery
Authors: Chetna Modi, Varsha Gadhvi and Bhupendra G. PrajapatiDue to the complexities of the eye's anatomy and physiology, achieving targeted drug delivery with minimal harm to healthy eye tissues has proven to be difficult. The focus of the review is on the potential of lipid and polymer micelle-based drug delivery systems, specifically nanomicelles, to overcome these challenges and improve the absorption of insoluble drugs. Nanomicelles offer several advantages, such as enhanced dr Read More
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Synthesis of Gold Nanoparticles Using Cucurbitacin E-Glycoside and Methyl Gallate Isolated from Citrullus colocynthis L. Fruit and Evaluation of their Antibacterial and Antibiofilm Activities
Authors: Achyut Adhikari, Asmita Sapkota, Syed Muhammad Zaki Shah, Kapil Aryal and Prajwal AcharyaIntroductionMetal nanoparticles have received much attention due to their unique physical dynamics, chemical reactivity, and promising biological applications. Green synthesis using natural compounds is an alternative to traditional chemical methods for the synthesis of nanoparticles.Materials and MethodsHerein, two secondary metabolites were isolated from different fractions of methanolic extract of Citrullus colocynthis (bitt Read More
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Soluplus-Stabilized Nimodipine-Entrapped Spanlastic Formulations Prepared with Edge Activator (Tween20): Comparative Physicochemical Evaluation
Authors: Hussein K. Alkufi and Hanan J. KassabBackgroundNimodipine (ND) is a vasodilator drug that is used for acute subarachnoid hemorrhage. It has a predominant hydrophobic property, causing low solubility and low bioavailability. Spanlastics are elastic nanovesicular systems based on non-ionic surfactants and edge activators as major components. The goal of this work is to formulate ND as spanlastic nanovesicles to improve the drug's bioavailability.MethodsSpa Read More
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Enhanced Transdermal Delivery of Cilnidpine Via Ultradeformable Vesicle Loaded Patch: Statistical Optimization, Characterization and Pharmacokinetic Assessment
Authors: Dagada Maheswara Reddy and Mothilal MohanObjectiveThe study aimed to address the limitations of oral delivery and enhance the bioavailability of Cilnidipine (often prescribed as antihypertensive drug) (CND) through the development of transdermal patches containing ultra-deformable transferosomes.MethodsCND, known for its low oral bioavailability and adverse effects, was encapsulated in transferosomes using a thin film hydration method. Seventeen fo Read More
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