Current Organic Chemistry - Volume 29, Issue 15, 2025

The review describes the oxidative addition of sulfonamides to allylic derivatives. The direction of the sulfonamidation reaction depends on various factors, such as the type of allylic substrate, solvent, oxidant, and the reactivity of the sulfonamide. Intramolecular cyclization of allyl sulfonamides is a simple method for obtaining nitrogen-containing heterocyclic compounds with diverse structures. Reactions between O-allylic substr Read More

Molecular photoswitches represent a dynamic and ever-growing research area based on the ability of molecules to convert (switch) between cis-(Z) and trans-(E) isomers. Azobenzenes are the most popular and widely employed Z-E photoswitchable molecules in the development of photoresponsive, multifunctional smart materials for various applications. The promising avenues in this field include molecular fine-tuni Read More

Various phenazine scaffolds are reputed for their significant biological activities. The majority of them can be obtained from natural sources. Other phenazine derivatives, especially benzo[a]phenazines, are found to possess immense biological efficacies, including antimicrobial, antifungal, anticancer, antileukemic, antitumor activities, etc. Constant efforts have been made to increase the biological efficacies by using fusing Read More

Pyridines/Dihydropyridines is a basic 6-membered organic aza-heterocyclic compound that has garnered the attention of many researchers in recent times. These molecules have been reported with a diverse range of pharmacological activities like anti-coagulant, antileishmanial and anti-trypanosomal, antitubercular agents, anti-microbial, antioxidant, HIV-1 protease inhibitors, anti-cancer, cardiovascular disease, etc. This Read More

Selectfluor, bis(tetrafluoroborate)[1-chloromethyl-4-fluoro-1,4-diazoniabicyclo-[2.2.2] octane] is an extraordinarily stable solid with exceptional properties, such as strong solubility and stability in polar solvents, minimal toxicity, excellent thermal stability, and utility as an oxidant. One of the electrophilic fluorinating compounds that is most frequently employed in fluorination reactions is Selectfluor. In this mini-review, we hav Read More

The field of biocatalysis has blossomed exponentially over the past decades and revolutionized chemical synthesis, providing greener and sustainable methods for preparing numerous organic molecules at bench and industrial scales and in high stereoselective mode for the chiral ones. However, despite the tremendous progress, researchers still have room to contribute significantly to the field, especially in the valorizati Read More