Current Cancer Therapy Reviews - Volume 18, Issue 3, 2022

Oral squamous cell carcinoma (OSCC), one of the most common types of oral cancer, is a significant cause of morbidity and mortality worldwide. OSCC is typically treated with a multidisciplinary approach that includes surgery, chemotherapy, and radiation after a definitive oral cancer diagnosis. Conventional chemotherapy drugs, on the other hand, may be ineffective and have a variety of side effects. Many techniques Read More

Background: Herbal medicines have been used for thousands of years due to their pharmacological activities against different types of human disorders. The biological effectiveness and pharmacological activities of herbal medicines are mainly due to the presence of different kinds of phytoconstituents, commonly called secondary metabolites. Isoflavones are naturally present in different types of plants and food mater Read More

Background: Currently, synthetic therapeutic drugs used in cancer treatment are targeting cancerous tissues that also affect noncancerous dividing cells, which exhibit side effects that decrease the immune response and affect the quality of life. Traditional/ natural products are well proven for a variety of therapeutically active chemical constituents. Caffeic acid phenethyl ester (CAPE) is one of the bioactive molecules found in the Read More

Background: Despite remarkable advancement in screening, diagnosis, and treatment modalities, cancer remains the second leading cause of death globally. Chemoprevention is considered to be a potential strategy for dealing with cancer incidence and mortality. The present demand for a less toxic well-tolerated natural anticancer compound that can be used for chemoprevention has drawn the attention towards D-limone Read More

Gastric cancer, with more than 1 million cases all over the globe, is a leading contributor to cancer mortality. In the recent past, the evolution of target therapies and the refining of the already existing chemotherapy have widened the therapeutic choices for advanced gastric cancer to increase survival. In addition, more studies have been conducted all over the globe to extensively evaluate epigenomic and genomic het Read More

Background: Early detection of cancer can be done using machine learning approaches with high precision. A brain tumor is a very dangerous disease that may cause the death of cancerous patients. Every year, thousands of people die from that disease all over the world. Proper detection of cancerous cells in the body can save their lives. Methods: To segment the brain tumor region through brain MR images and to classify Read More

Background: Triple-negative breast cancer cases with no available targeted therapy and advanced cases of luminal and HER2+ that become resistant to available state-of-the-art treatments are priorities in cancer research. Immune checkpoint blockade, particularly PDL1/PD1 inhibition, is suggested as a potential option for these patients suffering from several other types of cancers, such as melanoma. However, the exact Read More