Theranostics and Nanoparticular Approaches for the Treatment of Oral Squamous Cell Carcinoma

Oral squamous cell carcinoma (OSCC), one of the most common types of oral cancer, is a significant cause of morbidity and mortality worldwide. OSCC is typically treated with a multidisciplinary approach that includes surgery, chemotherapy, and radiation after a definitive oral cancer diagnosis. Conventional chemotherapy drugs, on the other hand, may be ineffective and have a variety of side effects. Many techniques for treating and diagnosing various types of oral cancer have been proven and approved, while others are currently being researched in clinical trials. This mini-review aimed to explain the current preclinical status of nano-based techniques for diagnosing and treating OSCC successfully. This mini compilation also highlights new theranostics approaches for treating squamous cell carcinoma (OSCC). Cancer biomarker detection has also been improved thanks to nanotechnology, which has made it faster and more sensitive. Various nanoparticles have been used as innovation drivers to overcome these constraints and enhance in situ drug delivery.