Current Organic Chemistry - Volume 29, Issue 13, 2025

Although a number of Lewis acids based on boron have been identified thus far, tris(pentafluorophenyl) borane [B(C6F5)3] (henceforth, BCF) has drawn the greatest interest from the synthetic chemistry community. Due to its commercial availability and thermal stability, BCF has been thoroughly investigated in organic and materials chemistry for its potential as a Lewis acid catalyst. The last two decades have witnesse Read More

A series of asymmetrical spirohomo- and methanofullerenes were synthesized for the first time in reactions of selective cycloaddition of adamantane diazo compounds to C60 fullerene in the presence of the catalyst Pd(PPh3)2Cl2. Adamantane diazoalkanes were obtained in situ in the oxidation reactions of adamantane hydrazones with manganese oxide MnO2. It has been established that the presence of adamantyl on Read More

To improve the activity of isatin-1,2,3-triazole hybrids as anti-cancer agents, new derivatives of isatin-thiosemicarbazone-1,2,3-triazoles 9-16 were designed and synthesized via the condensation of isatin-1,2,3-triazole hybrids 1-8 with thiosemicarbazide. Spectral and elemental analysis confirmed the structure of the prepared derivatives 9-16. Also, as anticancer agents, the latter derivatives were screened against three Read More

In this study, a simple, mild, and environmentally friendly process was used for the pseudo-seven component reaction between readily available benzene-1,3,5-tricarboxylic acid, isocyano-cyclohexane, and various aldehydes. This rapid method produced the tris-cyclohexylamino-oxo-benzene-1,3,5-tricarboxylates in relatively acceptable and more reasonable reaction times (10-15 min) and high achievable efficiencies (85-95%) Read More