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2000
Volume 21, Issue 4
  • ISSN: 1573-3947
  • E-ISSN: 1875-6301

Abstract

Background

Ovarian fibromas are sex cord-stromal tumors accounting for 4% of all ovarian tumors. They are benign, solid ovarian tumors commonly encountered in perimenopausal and postmenopausal women. They are usually asymptomatic or present with vague symptoms like abdominal pain. This makes their pre-operative diagnosis difficult.

Case Report

The present case report briefs the finding of ovarian fibroma in a 59-year-old postmenopausal woman presenting with dull aching lower abdominal pain, misdiagnosed as broad ligament fibroid on ultrasonography and malignant ovarian mass on MRI. She underwent exploratory laparotomy with total abdominal hysterectomy and bilateral salpingo-oophorectomy. Intraoperative findings included a right-sided smooth, solid, freely mobile ovarian mass of size 4x5 cm, uterus and left ovary were atrophic, with healthy bilateral fallopian tubes. Her histopathology report revealed ovarian fibroma with minimal nuclear atypia.

Conclusion

Ovarian fibromas are common benign solid ovarian tumors, that are difficult to diagnose pre-operatively, and often confused with uterine or broad ligament fibroids due to their similar clinical and radiological presentations. Hence, the clinician should keep ovarian fibromas as one of the differentials in the diagnosis of solid adnexal masses mimicking broad ligament fibroids.

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2024-05-15
2025-09-02

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References

  1. ThrallM.M. PaleyP. PizerE. GarciaR. GoffB.A. Patterns of spread and recurrence of sex cord-stromal tumors of the ovary.Gynecol. Oncol.2011122224224510.1016/j.ygyno.2011.03.020 21481441
     [Google Scholar]
  2. SchultzK.A.P. HarrisA.K. SchneiderD.T. YoungR.H. BrownJ. GershensonD.M. DehnerL.P. HillD.A. MessingerY.H. FrazierA.L. Ovarian sex cord-stromal tumors.J. Oncol. Pract.2016121094094610.1200/JOP.2016.016261 27858560
     [Google Scholar]
  3. Al HarbiR. McNeishI.A. El-BahrawyM. Ovarian sex cord-stromal tumors: an update on clinical features, molecular changes, and management.Int. J. Gynecol. Cancer202131216116810.1136/ijgc‑2020‑002018 33414107
     [Google Scholar]
  4. LeungS.W. YuenP.M. Ovarian fibroma: a review on the clinical characteristics, diagnostic difficulties, and management options of 23 cases.Gynecol. Obstet. Invest.20066211610.1159/000091679 16498263
     [Google Scholar]
  5. NumanogluC. KuruO. SakinciM. AkbayırO. UlkerV. Ovarian fibroma/fibrothecoma: Retrospective cohort study shows limited value of risk of malignancy index score.Aust. N. Z. J. Obstet. Gynaecol.201353328729210.1111/ajo.12090 23611791
     [Google Scholar]
  6. BoujoualM. HakimiI. KouachJ. OukabliM. MoussaouiD.R. DehayniM. Large twisted ovarian fibroma in menopausal women: a case report.Pan Afr. Med. J.20152032210.11604/pamj.2015.20.322.5998 26175813
     [Google Scholar]
  7. AbdelazimI. Abu-FazaM. AbdelrazekK. AmerO. ShikanovaS. ZhurabekovaG. Ovarian fibroma commonly misdiagnosed as uterine leiomyoma.Gynecol. Minim. Invasive Ther.202091363810.4103/GMIT.GMIT_131_18 32090012
     [Google Scholar]
  8. ParwateN.S. PatelS.M. AroraR. GuptaM. Ovarian Fibroma: A Clinico-pathological study of 23 cases with review of literature.J. Obstet. Gynaecol. India201666646046510.1007/s13224‑015‑0717‑6 27821988
     [Google Scholar]
  9. ChechiaA. AttiaL. TemimeR.B. MakhloufT. KoubaaA. Incidence, clinical analysis, and management of ovarian fibromas and fibrothecomas.Am. J. Obstet. Gynecol.20081995473.e1473.e410.1016/j.ajog.2008.03.053 18501324
     [Google Scholar]
  10. MohapatraV. PatraS. NayakM. GhareiR. SahooN. Cellular fibroma of ovary coexisting with proliferative endometrium post menopause: A Rare Presentation.J. Clin. Diagn. Res.2017117QD05QD0710.7860/JCDR/2017/27199.10247 28892985
     [Google Scholar]
  11. Gowthami KrishnaB. IndiraI. An unusal presentation of mamoth pseudo broad ligament leiomyoma with cystic degeneratons and hemorrhages: Case report.Ind. J. Obstet Gynecol. Res.20216222222410.18231/j.ijogr.2019.051
     [Google Scholar]
  12. ShanmughamD. ReddyS.M. GunasinghB. Degenerated broad ligament fibroid mimicking ovarian cyst: A case report.South. Asi. J. Case Rep. Rev.2023101242610.18231/j.sajcrr.2023.005
     [Google Scholar]
  13. SinghL. GuptaT. KumariS. GuptaS. True broad ligament fibroid mimicking ovarian mass in a postmenopausal woman.Int. J. Reprod. Contracept. Obstet. Gynecol.2019872910291210.18203/2320‑1770.ijrcog20193067
     [Google Scholar]
  14. Sh HassanA.A. AlsultanA.A. Al GhamdiR.K. AlbluwiN.M. AljameaJ.H. AlHammadiH.M. AlzakariM.J. AlmisbahM.H. AlsubaieF.A. AlajmiM.S. Uterine tumor resembling sex-cord tumor: A Case Report.Cureus20201212e1201010.7759/cureus.12010 33324531
     [Google Scholar]
  15. ShenY. LiangY. ChengX. LuW. XieX. WanX. Ovarian fibroma/fibrothecoma with elevated serum CA125 level.Medicine20189734e1192610.1097/MD.0000000000011926 30142807
     [Google Scholar]
  16. ChaM.Y. RohH.J. YouS.K. LeeS.H. ChoH.J. KwonY.S. Meigs’ syndrome with elevated serum CA 125 level in a case of ovarian fibrothecoma.Eur. J. Gynaecol. Oncol.2014356734737 25556284
     [Google Scholar]
  17. ZhaoC. VinhT.N. McManusK. DabbsD. BarnerR. VangR. Identification of the most sensitive and robust immunohistochemical markers in different categories of ovarian sex cord-stromal tumors.Am. J. Surg. Pathol.200933335436610.1097/PAS.0b013e318188373d 19033865
     [Google Scholar]
  18. KimB. Extra-ovarian cellular fibroma: A case report and review of the literature.Hum Pathol Rep20222930066810.1016/j.hpr.2022.300668
     [Google Scholar]
  19. MakC.W. TzengW.S. ChenC.Y. Computed tomography appearance of ovarian fibrothecomas with and without torsion.Acta Radiol.200950557057510.1080/02841850902896163 19455450
     [Google Scholar]
  20. YenP. KhongK. LambaR. CorwinM.T. GerscovichE.O. Ovarian fibromas and fibrothecomas: sonographic correlation with computed tomography and magnetic resonance imaging: a 5-year single-institution experience.J. Ultrasound Med.2013321131810.7863/jum.2013.32.1.13 23269706
     [Google Scholar]
  21. GuptaN ShikhaD RoyA SinghS Broad ligament fibroid as an incidental finding in an unruptured ectopic. Int. J. Clin. Obstet. Gynaeco.2022645610.33545/gynae.2022.v6.i4a.1188
     [Google Scholar]
  22. NaveO. ShorY. BarR. SegalE.E. SigronM. A new treatment for breast cancer using a combination of two drugs: AZD9496 and palbociclib.Sci. Rep.2024141130710.1038/s41598‑023‑48305‑z 38225243
     [Google Scholar]
  23. NaveO.P. SigronM. A mathematical model for the treatment of melanoma with the BRAF/MEK Inhibitor and Anti-PD-1.Appl. Sci.202212231247410.3390/app122312474
     [Google Scholar]
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Sex Cord Stromal Tumor Masquerading as Broad Ligament Fibroid in a Postmenopausal Woman: Lessons Learned from a Case Report
Curr Cancer Ther Rev 21, 586 (2025); https://doi.org/10.2174/0115733947290124240502074850
/content/journals/cctr/10.2174/0115733947290124240502074850
/content/journals/cctr/10.2174/0115733947290124240502074850
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  • Article Type:     Case Report
Keyword(s): ovarian fibroid; Ovarian fibroma; ovarian tumor; pelvic tumor; postmenopausal woman; sex cord-stromal tumor

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