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2000
Volume 21, Issue 3
  • ISSN: 1573-3947
  • E-ISSN: 1875-6301

Abstract

Background

Breast cancer incidence and mortality rates are rising worldwide, which presents a formidable challenge for women. The advancement of targeted drug therapies offers promising avenues for treatment, but resource constraints prevent their widespread implementation in advanced clinical trials, highlighting the need for sustained research funding. Nutritional support is critical in cancer management, affecting key cancer hallmarks. The anti-inflammatory effects of exercise and a healthy diet are critical in reducing cancer incidence and tumor growth. A comprehensive approach to breast cancer treatment requires addressing health challenges and psychological symptoms.

Objective

In this context, we aim to address modifiable risk factors, including nutrition, physical activity, and psychosocial factors, which can serve as non-pharmacological adjuncts in reducing breast cancer risk, incidence, and mortality.

Methods

This study conducted a thorough literature search on breast cancer, nutrition, physical activity, psychosocial problems, clinical trial/study, mechanisms, and . The search was performed using multiple search engines and the main keywords, and only English publications until August 2023 were included.

Results

Nutrition plays a critical role in influencing breast cancer risk, but its exact role needs to be explored. Diet diversity and exercise are recommended to reduce risk, while psychosocial support is vital for patient well-being.

Conclusion

In light of rising global breast cancer challenges, our study underscores the urgent need for enhanced clinical trial availability, exploration of nutrition-cancer links, and refined psychosocial interventions to comprehensively address prevention and treatment.

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2025-11-04
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References

  1. SungH. FerlayJ. SiegelR.L. LaversanneM. SoerjomataramI. JemalA. BrayF. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.CA Cancer J. Clin.202171320924910.3322/caac.2166033538338
    [Google Scholar]
  2. FengY. SpeziaM. HuangS. YuanC. ZengZ. ZhangL. JiX. LiuW. HuangB. LuoW. LiuB. LeiY. DuS. VuppalapatiA. LuuH.H. HaydonR.C. HeT.C. RenG. Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis.Genes Dis.2018527710610.1016/j.gendis.2018.05.00130258937
    [Google Scholar]
  3. NascimentoR.G. OtoniK.M. Histological and molecular classification of breast cancer: What do we know?Mastology202030e2020002410.29289/25945394202020200024
    [Google Scholar]
  4. WatkinsE.J. Overview of breast cancer.JAAPA20193210131710.1097/01.JAA.0000580524.95733.3d31513033
    [Google Scholar]
  5. ŁukasiewiczS. CzeczelewskiM. FormaA. BajJ. SitarzR. StanisławekA. Breast cancer—epidemiology, risk factors, classification, prognostic markers, and current treatment strategies—an updated review.Cancers20211317428710.3390/cancers1317428734503097
    [Google Scholar]
  6. SmolarzB. NowakA.Z. RomanowiczH. Breast cancer—epidemiology, classification, pathogenesis and treatment (review of literature).Cancers20221410256910.3390/cancers1410256935626173
    [Google Scholar]
  7. VishwakarmaG. NdetanH. DasD.N. GuptaG. SuryavanshiM. MehtaA. SinghK.P. Reproductive factors and breast cancer risk: A meta-analysis of case–control studies in Indian women.South Asian J. Cancer201982808410.4103/sajc.sajc_317_1831069183
    [Google Scholar]
  8. DalyA.A. RolphR. CutressR.I. CopsonE.R. A review of modifiable risk factors in young women for the prevention of breast cancer.Breast Cancer20211324125710.2147/BCTT.S26840133883932
    [Google Scholar]
  9. SoldatiL. Di RenzoL. JirilloE. AsciertoP.A. MarincolaF.M. De LorenzoA. The influence of diet on anti-cancer immune responsiveness.J. Transl. Med.20181617510.1186/s12967‑018‑1448‑029558948
    [Google Scholar]
  10. KapinovaA. KubatkaP. GolubnitschajaO. KelloM. ZuborP. SolarP. PecM. Dietary phytochemicals in breast cancer research: Anticancer effects and potential utility for effective chemoprevention.Environ. Health Prev. Med.20182313610.1186/s12199‑018‑0724‑130092754
    [Google Scholar]
  11. RockC.L. ThomsonC. GanslerT. GapsturS.M. McCulloughM.L. PatelA.V. AndrewsK.S. BanderaE.V. SpeesC.K. RobienK. HartmanS. SullivanK. GrantB.L. HamiltonK.K. KushiL.H. CaanB.J. KibbeD. BlackJ.D. WiedtT.L. McMahonC. SloanK. DoyleC. American cancer society guideline for diet and physical activity for cancer prevention.CA Cancer J. Clin.202070424527110.3322/caac.2159132515498
    [Google Scholar]
  12. BrownJ.C. ZhangS. LigibelJ.A. IrwinM.L. JonesL.W. CampbellN. PollakM.N. SorrentinoA. CartmelB. HarriganM. TolaneyS.M. WinerE.P. NgK. AbramsT.A. SanftT. DouglasP.S. HuF.B. FuchsC.S. MeyerhardtJ.A. Effect of exercise or metformin on biomarkers of inflammation in breast and colorectal cancer: A randomized trial.Cancer Prev. Res.202013121055106210.1158/1940‑6207.CAPR‑20‑018832859615
    [Google Scholar]
  13. WennerbergE. LhuillierC. RybsteinM.D. DannenbergK. RudqvistN.P. KoelwynG.J. JonesL.W. DemariaS. Exercise reduces immune suppression and breast cancer progression in a preclinical model.Oncotarget202011445246110.18632/oncotarget.2746432064049
    [Google Scholar]
  14. ChenX. WangQ. ZhangY. XieQ. TanX. Physical activity and risk of breast cancer: A meta-analysis of 38 cohort studies in 45 study reports.Value Health201922110412810.1016/j.jval.2018.06.02030661625
    [Google Scholar]
  15. RashidA. AqeelM. MalikB. SalimS. The prevalence of psychiatric disorders in breast cancer patients; A cross-sectional study of breast cancer patients experience in Pakistan.Nat-Nurt J Psychol.20211117
    [Google Scholar]
  16. AlagizyH.A. SoltanM.R. SolimanS.S. HegazyN.N. GoharS.F. Anxiety, depression and perceived stress among breast cancer patients: Single institute experience.Middle East Current Psychiatry20202712910.1186/s43045‑020‑00036‑x
    [Google Scholar]
  17. YeJ.C. FormentiS.C. Integration of radiation and immunotherapy in breast cancer - Treatment implications.Breast201838667410.1016/j.breast.2017.12.00529253718
    [Google Scholar]
  18. RoheelA. KhanA. AnwarF. AkbarZ. AkhtarM.F. Imran KhanM. SohailM.F. AhmadR. Global epidemiology of breast cancer based on risk factors: A systematic review.Front Oncol.202313124009810.3389/fonc.2023.124009837886170PMC10598331
    [Google Scholar]
  19. FioletT. SrourB. SellemL. Kesse-GuyotE. AllèsB. MéjeanC. DeschasauxM. FassierP. Latino-MartelP. BeslayM. HercbergS. LavaletteC. MonteiroC.A. JuliaC. TouvierM. Consumption of ultra-processed foods and cancer risk: Results from NutriNet-Santé prospective cohort.BMJ2018360k32210.1136/bmj.k32229444771
    [Google Scholar]
  20. BousquenaudM. FicoF. SolinasG. RüeggC. Santamaria-MartínezA. Obesity promotes the expansion of metastasis-initiating cells in breast cancer.Breast Cancer Res.201820110410.1186/s13058‑018‑1029‑430180888
    [Google Scholar]
  21. OrecchioniS. GregatoG. Martin-PaduraI. ReggianiF. BraidottiP. MancusoP. CalleriA. QuarnaJ. MarighettiP. AldeniC. PruneriG. MartellaS. ManconiA. PetitJ.Y. RietjensM. BertoliniF. Complementary populations of human adipose CD34+ progenitor cells promote growth, angiogenesis, and metastasis of breast cancer.Cancer Res.201373195880589110.1158/0008‑5472.CAN‑13‑082123918796
    [Google Scholar]
  22. GravenaA.A.F. Romeiro LopesT.C. DemittoM.O. BorghesanD.H.P. Dell’ AgnoloC.M. BrischiliariS.C.R. CarvalhoM.D.B. PellosoS.M. The obesity and the risk of breast cancer among pre and postmenopausal women.Asian Pac. J. Cancer Prev.20181992429243630255696
    [Google Scholar]
  23. PrenticeR.L. AragakiA.K. Van HornL. ThomsonC.A. BeresfordS.A.A. RobinsonJ. SnetselaarL. AndersonG.L. MansonJ.E. AllisonM.A. RossouwJ.E. HowardB.V. Low-fat dietary pattern and cardiovascular disease: Results from the women’s health initiative randomized controlled trial.Am. J. Clin. Nutr.20171061354310.3945/ajcn.117.15327028515068
    [Google Scholar]
  24. BissonauthV. ShatensteinB. GhadirianP. Nutrition and breast cancer among sporadic cases and gene mutation carriers: An overview.Cancer Detect. Prev.2008321526410.1016/j.cdp.2008.01.00518400416
    [Google Scholar]
  25. FarvidM.S. ChoE. ChenW.Y. EliassenA.H. WillettW.C. Dietary protein sources in early adulthood and breast cancer incidence: Prospective cohort study.BMJ2014348jun10 3g343710.1136/bmj.g343724916719
    [Google Scholar]
  26. DialloA. DeschasauxM. Latino-MartelP. HercbergS. GalanP. FassierP. AllèsB. GuéraudF. PierreF.H. TouvierM. Red and processed meat intake and cancer risk: Results from the prospective NutriNet‐Santé cohort study.Int. J. Cancer2018142223023710.1002/ijc.3104628913916
    [Google Scholar]
  27. PouchieuC. DeschasauxM. HercbergS. Druesne-PecolloN. Latino-MartelP. TouvierM. Prospective association between red and processed meat intakes and breast cancer risk: Modulation by an antioxidant supplementation in the SU.VI.MAX randomized controlled trial.Int. J. Epidemiol.20144351583159210.1093/ije/dyu13424994839
    [Google Scholar]
  28. SamavatH. UrsinG. EmoryT.H. LeeE. WangR. TorkelsonC.J. DostalA.M. SwensonK. LeC.T. YangC.S. YuM.C. YeeD. WuA.H. YuanJ.M. KurzerM.S. A randomized controlled trial of green tea extract supplementation and mammographic density in postmenopausal women at increased risk of breast cancer.Cancer Prev. Res.2017101271071810.1158/1940‑6207.CAPR‑17‑018728904061
    [Google Scholar]
  29. AmbrosoneC.B. ZirpoliG.R. HutsonA.D. McCannW.E. McCannS.E. BarlowW.E. KellyK.M. CanniotoR. Sucheston-CampbellL.E. HershmanD.L. UngerJ.M. MooreH.C.F. StewartJ.A. IsaacsC. HobdayT.J. SalimM. HortobagyiG.N. GralowJ.R. BuddG.T. AlbainK.S. Dietary supplement use during chemotherapy and survival outcomes of patients with breast cancer enrolled in a cooperative group clinical trial (SWOG S0221).J. Clin. Oncol.202038880481410.1200/JCO.19.0120331855498
    [Google Scholar]
  30. KeshavarziZ. JanghorbanR. AlipourS. TahmasebiS. JokarA. The effect of vitamin D and E vaginal suppositories on tamoxifen-induced vaginal atrophy in women with breast cancer.Support. Care Cancer20192741325133410.1007/s00520‑019‑04684‑630729333
    [Google Scholar]
  31. ChlebowskiR.T. AragakiA.K. AndersonG.L. PanK. NeuhouserM.L. MansonJ.E. ThomsonC.A. Mossavar-RahmaniY. LaneD.S. JohnsonK.C. Wactawski-WendeJ. SnetselaarL. RohanT.E. LuoJ. BaracA. PrenticeR.L. Women’s Health Initiative Dietary modification and breast cancer mortality: Long-term follow-up of the women’s health initiative randomized trial.J. Clin. Oncol.202038131419142810.1200/JCO.19.0043532031879
    [Google Scholar]
  32. ZickS.M. ColacinoJ. CornellierM. KhabirT. SurnowK. DjuricZ. Fatigue reduction diet in breast cancer survivors: A pilot randomized clinical trial.Breast Cancer Res. Treat.2017161229931010.1007/s10549‑016‑4070‑y27913933
    [Google Scholar]
  33. ZunigaK.E. ParmaD.L. MuñozE. SpaniolM. WargovichM. RamirezA.G. Dietary intervention among breast cancer survivors increased adherence to a mediterranean-style, anti-inflammatory dietary pattern: the rx for better breast health randomized controlled trial.Breast Cancer Res. Treat.2019173114515410.1007/s10549‑018‑4982‑930259284
    [Google Scholar]
  34. TeixeiraL.L. CostaG.R. DörrF.A. OngT.P. PintoE. LajoloF.M. HassimottoN.M.A. Potential antiproliferative activity of polyphenol metabolites against human breast cancer cells and their urine excretion pattern in healthy subjects following acute intake of a polyphenol-rich juice of grumixama (Eugenia brasiliensis Lam.).Food Funct.2017862266227410.1039/C7FO00076F28541359
    [Google Scholar]
  35. ButallaA.C. CraneT.E. PatilB. WertheimB.C. ThompsonP. ThomsonC.A. Effects of a carrot juice intervention on plasma carotenoids, oxidative stress, and inflammation in overweight breast cancer survivors.Nutr. Cancer201264233134110.1080/01635581.2012.65077922292424
    [Google Scholar]
  36. HardmanW.E. PrimeranoD.A. LegenzaM.T. MorganJ. FanJ. DenvirJ. Dietary walnut altered gene expressions related to tumor growth, survival, and metastasis in breast cancer patients: A pilot clinical trial.Nutr. Res.201966829410.1016/j.nutres.2019.03.00430979659
    [Google Scholar]
  37. RockenbachG. Di PietroP.F. AmbrosiC. BoaventuraB.C. VieiraF.G. CrippaC.G. Da SilvaE.L. FaustoM.A. Dietary intake and oxidative stress in breast cancer: Before and after treatments.Nutr. Hosp.201126473774422470018
    [Google Scholar]
  38. HarmonB.E. MorimotoY. BeckfordF. FrankeA.A. StanczykF.Z. MaskarinecG. Oestrogen levels in serum and urine of premenopausal women eating low and high amounts of meat.Public Health Nutr.20141792087209310.1017/S136898001300255324050121
    [Google Scholar]
  39. MouroutiN. KontogianniM.D. PapavagelisC. PlytzanopoulouP. VassilakouT. PsaltopoulouT. MalamosN. LinosA. PanagiotakosD.B. Meat consumption and breast cancer: A case–control study in women.Meat Sci.201510019520110.1016/j.meatsci.2014.10.01925460125
    [Google Scholar]
  40. WajszczykB. CharzewskaJ. GodlewskiD. ZemłaB. NowakowskaE. KozaczkaM. ChilimoniukM. PathakD.R. Consumption of dairy products and the risk of developing breast cancer in polish women.Nutrients20211312442010.3390/nu1312442034959971
    [Google Scholar]
  41. Aguilera-BuenosvinosI. Fernandez-LazaroC.I. Romanos-NanclaresA. GeaA. Sánchez-BayonaR. Martín-MorenoJ.M. Martínez-GonzálezM.Á. ToledoE. Dairy consumption and incidence of breast cancer in the ‘seguimiento universidad de navarra’ (SUN) project.Nutrients202113268710.3390/nu1302068733669972
    [Google Scholar]
  42. KhanS.A. ChattertonR.T. MichelN. BrykM. LeeO. IvancicD. HeinzR. ZallesC.M. HelenowskiI.B. JovanovicB.D. FrankeA.A. BoslandM.C. WangJ. HansenN.M. BethkeK.P. DewA. CoomesM. BerganR.C. Soy isoflavone supplementation for breast cancer risk reduction: A randomized phase II trial.Cancer Prev. Res.20125230931910.1158/1940‑6207.CAPR‑11‑025122307566
    [Google Scholar]
  43. WuA.H. SpicerD. GarciaA. TsengC.C. Hovanessian-LarsenL. ShethP. MartinS.E. HawesD. RussellC. MacDonaldH. TripathyD. SuM.Y. UrsinG. PikeM.C. Double-blind randomized 12-month soy intervention had no effects on breast mri fibroglandular tissue density or mammographic density.Cancer Prev. Res.201581094295110.1158/1940‑6207.CAPR‑15‑012526276750
    [Google Scholar]
  44. LuL.J.W. ChenN.W. BrunderD.G. NayeemF. NagamaniM. NishinoT.K. AndersonK.E. KhamapiradT. Soy isoflavones decrease fibroglandular breast tissue measured by magnetic resonance imaging in premenopausal women: A 2-year randomized double-blind placebo controlled clinical trial.Clin. Nutr. ESPEN20225215816810.1016/j.clnesp.2022.10.00736513449
    [Google Scholar]
  45. MaskarinecG. VerheusM. SteinbergF.M. AmatoP. CramerM.K. LewisR.D. MurrayM.J. YoungR.L. WongW.W. Various doses of soy isoflavones do not modify mammographic density in postmenopausal women.J. Nutr.2009139598198610.3945/jn.108.10291319321587
    [Google Scholar]
  46. ReitzL.K. BaptistaS.L. SantosE.S. HinnigP.F. RockenbachG. VieiraF.G.K. de AssisM.A.A. da SilvaE.L. BoaventuraB.C.B. PietroP.F.D. Diet quality is associated with serum antioxidant capacity in women with breast cancer: A cross sectional study.Nutrients202013111510.3390/nu1301011533396963
    [Google Scholar]
  47. DjuricZ. RenJ. BrownP.R. EllsworthJ.S. SenA. Lifestyle factors associated with serum N-3 fatty acid levels in breast cancer patients.Breast201221460861110.1016/j.breast.2012.02.00322377591
    [Google Scholar]
  48. de la Rosa OlivaF. Meneses GarcíaA. Ruiz CalzadaH. Astudillo de la VegaH. Bargalló RochaE. Lara-MedinaF. Alvarado MirandaA. Matus-SantosJ. Flores-DíazD. Oñate-AcuñaL.F. Gutiérrez-SalmeánG. Ruiz GarcíaE. IbarraA. Effects of omega-3 fatty acids supplementation on neoadjuvant chemotherapy-induced toxicity in patients with locally advanced breast cancer: a randomized, controlled, double-blinded clinical trial.Nutr. Hosp.201936476977610.20960/nh.233831192682
    [Google Scholar]
  49. KlecknerA.S. CulakovaE. KlecknerI.R. BelcherE.K. Demark-WahnefriedW. ParkerE.A. PadulaG.D.A. OntkoM. JanelsinsM.C. MustianK.M. PepponeL.J. Nutritional status predicts fatty acid uptake from fish and soybean oil supplements for treatment of cancer-related fatigue: Results from a phase II nationwide study.Nutrients202114118410.3390/nu1401018435011059
    [Google Scholar]
  50. ShenS. UngerJ.M. CrewK.D. TillC. GreenleeH. GralowJ. DakhilS.R. MinasianL.M. WadeJ.L.III FischM.J. HenryN.L. HershmanD.L. Omega-3 fatty acid use for obese breast cancer patients with aromatase inhibitor-related arthralgia (SWOG S0927).Breast Cancer Res. Treat.2018172360361010.1007/s10549‑018‑4946‑030159789
    [Google Scholar]
  51. El-BassiounyN.A. HelmyM.W. HassanM.A.E. KhedrG.A. The cardioprotective effect of vitamin D in breast cancer patients receiving adjuvant doxorubicin based chemotherapy.Clin. Breast Cancer202222435936610.1016/j.clbc.2022.01.00835241369
    [Google Scholar]
  52. PepponeL.J. HustonA.J. ReidM.E. RosierR.N. ZakhariaY. TrumpD.L. MustianK.M. JanelsinsM.C. PurnellJ.Q. MorrowG.R. The effect of various vitamin D supplementation regimens in breast cancer patients.Breast Cancer Res. Treat.2011127117117710.1007/s10549‑011‑1415‑421384167
    [Google Scholar]
  53. NaderiM. KordestaniH. SahebiZ. Khedmati ZareV. Amani-ShalamzariS. KavianiM. WiskemannJ. Molanouri ShamsiM. Serum and gene expression profile of cytokines following combination of yoga training and vitamin D supplementation in breast cancer survivors: A randomized controlled trial.BMC Womens Health20222219010.1186/s12905‑022‑01671‑835331230
    [Google Scholar]
  54. GoingC.C. AlexandrovaL. LauK. YehC.Y. FeldmanD. PitteriS.J. Vitamin D supplementation decreases serum 27-hydroxycholesterol in a pilot breast cancer trial.Breast Cancer Res. Treat.2018167379780210.1007/s10549‑017‑4562‑429116467
    [Google Scholar]
  55. JungS. EglestonB.L. ChandlerD.W. Van HornL. HyltonN.M. KlifaC.C. LasserN.L. LeBlancE.S. ParisK. ShepherdJ.A. SnetselaarL.G. StanczykF.Z. StevensV.J. DorganJ.F. Adolescent endogenous sex hormones and breast density in early adulthood.Breast Cancer Res.20151717710.1186/s13058‑015‑0581‑426041651
    [Google Scholar]
  56. ChattopadhyayS. SiddiquiS. AkhtarM.S. NajmM.Z. DeoS.V.S. ShuklaN.K. HusainS.A. Genetic polymorphisms of ESR1, ESR2, CYP17A1, and CYP19A1 and the risk of breast cancer: A case control study from North India.Tumour Biol.20143554517452710.1007/s13277‑013‑1594‑124430361
    [Google Scholar]
  57. ChangV.C. CotterchioM. BoucherB.A. JenkinsD.J.A. MireaL. McCannS.E. ThompsonL.U. Effect of dietary flaxseed intake on circulating sex hormone levels among postmenopausal women: A randomized controlled intervention trial.Nutr. Cancer201971338539810.1080/01635581.2018.151678930375890
    [Google Scholar]
  58. BoutasI. KontogeorgiA. DimitrakakisC. KalantaridouS.N. Soy isoflavones and breast cancer risk: A meta-analysis.In Vivo202236255656210.21873/invivo.1273735241506
    [Google Scholar]
  59. SinghB. SmithJ.A. AxelrodD.M. AmeriP. LevittH. DanoffA. LesserM. de AngelisC. Illa-BochacaI. LubitzS. HubermanD. DarvishianF. KleinbergD.L. Insulin-like growth factor-I inhibition with pasireotide decreases cell proliferation and increases apoptosis in pre-malignant lesions of the breast: A phase 1 proof of principle trial.Breast Cancer Res.201416646310.1186/s13058‑014‑0463‑125385439
    [Google Scholar]
  60. RigiraccioloD.C. NohataN. LappanoR. CirilloF. TaliaM. ScordamagliaD. GutkindJ.S. MaggioliniM. IGF-1/IGF-1R/FAK/YAP transduction signaling prompts growth effects in triple-negative breast cancer (TNBC) cells.Cells202094101010.3390/cells904101032325700
    [Google Scholar]
  61. NivethaR. ArvindhS. BabaA.B. GadeD.R. GopalG. KC. ReddyK.P. ReddyG.B. NaginiS. Nimbolide, a neem limonoid, inhibits angiogenesis in breast cancer by abrogating aldose reductase mediated IGF-1/PI3K/Akt signalling.Anticancer. Agents Med. Chem.202222142619263610.2174/187152062266622020411515135125086
    [Google Scholar]
  62. ChenW.J. TsaiJ.H. HsuL.S. LinC.L. HongH.M. PanM.H. Quercetin blocks the aggressive phenotype of triple-negative breast cancer by inhibiting IGF1/IGF1R-mediated EMT program.Yao Wu Shi Pin Fen Xi20212919811210.38212/2224‑6614.309035696220
    [Google Scholar]
  63. ReamM. Saez-ClarkeE. TaubC. DiazA. FrascaD. BlombergB.B. AntoniM.H. Brief post-surgical stress management reduces pro-inflammatory cytokines in overweight and obese breast cancer patients undergoing primary treatment.Frontiers in Bioscience-Landmark202227514810.31083/j.fbl270514835638415
    [Google Scholar]
  64. BrownK.A. Metabolic pathways in obesity-related breast cancer.Nat. Rev. Endocrinol.202117635036310.1038/s41574‑021‑00487‑033927368
    [Google Scholar]
  65. Ortiz-MonteroP. Londoño-VallejoA. VernotJ.P. Senescence-associated IL-6 and IL-8 cytokines induce a self- and cross-reinforced senescence/inflammatory milieu strengthening tumorigenic capabilities in the MCF-7 breast cancer cell line.Cell Commun. Signal.20171511710.1186/s12964‑017‑0172‑328472950
    [Google Scholar]
  66. MaY. RenY. DaiZ.J. WuC.J. JiY.H. XuJ. IL-6, IL-8 and TNF-α levels correlate with disease stage in breast cancer patients.Adv. Clin. Exp. Med.201726342142610.17219/acem/6212028791816
    [Google Scholar]
  67. PaixãoE.M.S. OliveiraA.C.M. PizatoN. Muniz-JunqueiraM.I. MagalhãesK.G. NakanoE.Y. ItoM.K. The effects of EPA and DHA enriched fish oil on nutritional and immunological markers of treatment naïve breast cancer patients: A randomized double-blind controlled trial.Nutr. J.20171617110.1186/s12937‑017‑0295‑929061183
    [Google Scholar]
  68. StasiewiczB. WadolowskaL. BiernackiM. SlowinskaM.A. DrozdowskiM. Hybrid dietary-blood inflammatory profiles and postmenopausal breast cancer: A case-control study.Nutrients20201211350310.3390/nu1211350333202561
    [Google Scholar]
  69. AkterR. Chan AhnJ. NaharJ. AwaisM. RamadhaniaZ.M. OhS.W. OhJ.H. KongB.M. RupaE.J. LeeD.W. YangD.C. Chan kangS. Pomegranate juice fermented by tannin acyl hydrolase and Lactobacillus vespulae DCY75 enhance estrogen receptor expression and anti-inflammatory effect.Front. Pharmacol.202213101010310.3389/fphar.2022.101010336249796
    [Google Scholar]
  70. HarrisR.E. Epidemiology of chronic disease: Global perspectives.Burlington, MAJones and Bartlett Learning2020 https://www.jblearning.com/catalog/productdetails/9781284151015?srsltid=AfmBOoprbhFgV_5bmjlZ3K6pWXnMFi8uvTmJ3XfWyiw8TnVPd0I5Am8n
    [Google Scholar]
  71. CunninghamC. O’ SullivanR. CaserottiP. TullyM.A. Consequences of physical inactivity in older adults: A systematic review of reviews and meta‐analyses.Scand. J. Med. Sci. Sports202030581682710.1111/sms.1361632020713
    [Google Scholar]
  72. BullardT. JiM. AnR. TrinhL. MackenzieM. MullenS.P. A systematic review and meta-analysis of adherence to physical activity interventions among three chronic conditions: Cancer, cardiovascular disease, and diabetes.BMC Public Health201919163610.1186/s12889‑019‑6877‑z31126260
    [Google Scholar]
  73. RezendeL.F.M. SáT.H. MarkozannesG. Rey-LópezJ.P. LeeI.M. TsilidisK.K. IoannidisJ.P.A. Eluf-NetoJ. Physical activity and cancer: An umbrella review of the literature including 22 major anatomical sites and 770 000 cancer cases.Br. J. Sports Med.2018521382683310.1136/bjsports‑2017‑09839129146752
    [Google Scholar]
  74. Lauby-SecretanB. ScocciantiC. LoomisD. GrosseY. BianchiniF. StraifK. International Agency for Research on Cancer Handbook Working Group International agency for research on cancer handbook working group. Body fatness and cancer-viewpoint of the IARC working group.N. Engl. J. Med.2016375879479810.1056/NEJMsr160660227557308
    [Google Scholar]
  75. AvgerinosK.I. SpyrouN. MantzorosC.S. DalamagaM. Obesity and cancer risk: Emerging biological mechanisms and perspectives.Metabolism20199212113510.1016/j.metabol.2018.11.00130445141
    [Google Scholar]
  76. HagarA. WangZ. KoyamaS. SerranoJ.A. MeloL. VargasS. CarpenterR. FoleyJ. Endurance training slows breast tumor growth in mice by suppressing Treg cells recruitment to tumors.BMC Cancer201919153610.1186/s12885‑019‑5745‑731164094
    [Google Scholar]
  77. LeeB. ChungW. Effects of aerobic exercise on cytokine expression in a breast cancer mouse model.Iran. J. Public Health2020491142010.18502/ijph.v49i1.304632309219
    [Google Scholar]
  78. Gomes-SantosI.L. AmoozgarZ. KumarA.S. HoW.W. RohK. TaleleN.P. CurtisH. KawaguchiK. JainR.K. FukumuraD. Exercise training improves tumor control by increasing CD8+ T-cell infiltration via CXCR3 signaling and sensitizes breast cancer to immune checkpoint blockade.Cancer Immunol. Res.20219776577810.1158/2326‑6066.CIR‑20‑049933839688
    [Google Scholar]
  79. GuoW. FensomG.K. ReevesG.K. KeyT.J. Physical activity and breast cancer risk: Results from the UK Biobank prospective cohort.Br. J. Cancer2020122572673210.1038/s41416‑019‑0700‑631919405
    [Google Scholar]
  80. ChanD.S.M. AbarL. CariolouM. NanuN. GreenwoodD.C. BanderaE.V. McTiernanA. NoratT. World cancer research fund international: Continuous update project—systematic literature review and meta-analysis of observational cohort studies on physical activity, sedentary behavior, adiposity, and weight change and breast cancer risk.Cancer Causes Control201930111183120010.1007/s10552‑019‑01223‑w31471762
    [Google Scholar]
  81. NyropK.A. DealA.M. ShacharS.S. BaschE. ReeveB.B. ChoiS.K. LeeJ.T. WoodW.A. AndersC.K. CareyL.A. DeesE.C. JollyT.A. Reeder-HayesK.E. KimmickG.G. KaruturiM.S. ReinboltR.E. SpecaJ.C. MussH.B. Patient-reported toxicities during chemotherapy regimens in current clinical practice for early breast cancer.Oncologist201924676277110.1634/theoncologist.2018‑059030552158
    [Google Scholar]
  82. O’HigginsC.M. BradyB. O’ConnorB. WalshD. ReillyR.B. The pathophysiology of cancer-related fatigue: Current controversies.Support. Care Cancer201826103353336410.1007/s00520‑018‑4318‑729961146
    [Google Scholar]
  83. YeoT.P. CannadayS. Cancer-related fatigue: Impact on patient quality of life and management approaches.Nursing: Res Rev.201556576
    [Google Scholar]
  84. HughesA. SulemanS. RimesK.A. MarsdenJ. ChalderT. Cancer-related fatigue and functional impairment – Towards an understanding of cognitive and behavioural factors.J. Psychosom. Res.202013411012710.1016/j.jpsychores.2020.11012732428784
    [Google Scholar]
  85. WeisJ. Cancer-related fatigue: Prevalence, assessment and treatment strategies.Expert Rev. Pharmacoecon. Outcomes Res.201111444144610.1586/erp.11.4421831025
    [Google Scholar]
  86. Meneses-EchávezJ.F. González-JiménezE. Ramírez-VélezR. Effects of supervised exercise on cancer-related fatigue in breast cancer survivors: A systematic review and meta-analysis.BMC Cancer20151517710.1186/s12885‑015‑1069‑425885168
    [Google Scholar]
  87. MijwelS. BackmanM. BolamK.A. OlofssonE. NorrbomJ. BerghJ. SundbergC.J. WengströmY. RundqvistH. Highly favorable physiological responses to concurrent resistance and high-intensity interval training during chemotherapy: the OptiTrain breast cancer trial.Breast Cancer Res. Treat.201816919310310.1007/s10549‑018‑4663‑829349712
    [Google Scholar]
  88. JohnssonA. DemmelmaierI. SjövallK. WagnerP. OlssonH. TornbergÅ.B. A single exercise session improves side-effects of chemotherapy in women with breast cancer: An observational study.BMC Cancer2019191107310.1186/s12885‑019‑6310‑031703567
    [Google Scholar]
  89. RaminC. SchaefferM.L. ZhengZ. ConnorA.E. Hoffman-BoltonJ. LauB. VisvanathanK. All-cause and cardiovascular disease mortality among breast cancer survivors in CLUE II, a long-standing community-based cohort.J. Natl. Cancer Inst.2021113213714510.1093/jnci/djaa09632634223
    [Google Scholar]
  90. ZhangS. LiuX. Bawa-KhalfeT. LuL.S. LyuY.L. LiuL.F. YehE.T.H. Identification of the molecular basis of doxorubicin-induced cardiotoxicity.Nat. Med.201218111639164210.1038/nm.291923104132
    [Google Scholar]
  91. FoulkesS.J. HowdenE.J. HaykowskyM.J. AntillY. SalimA. NightingaleS.S. LoiS. ClausP. JanssensK. MitchellA.M. WrightL. CostelloB.T. LindqvistA. BurnhamL. WallaceI. DalyR.M. FraserS.F. La GercheA. Exercise for the prevention of anthracycline-induced functional disability and cardiac dysfunction: The BREXIT Study.Circulation2023147753254510.1161/CIRCULATIONAHA.122.06281436342348
    [Google Scholar]
  92. DozicS. HowdenE.J. BellJ.R. MellorK.M. DelbridgeL.M.D. WeeksK.L. Cellular mechanisms mediating exercise-induced protection against cardiotoxic anthracycline cancer therapy.Cells2023129131210.3390/cells1209131237174712
    [Google Scholar]
  93. JacquinotQ. MeneveauN. FalcozA. BouhaddiM. RouxP. DeganoB. ChatotM. CurtitE. MansiL. PaillardM.J. BazanF. ChaigneauL. DobiE. MeynardG. VernereyD. PivotX. MouginF. Cardiotoxicity is mitigated after a supervised exercise program in HER2-positive breast cancer undergoing adjuvant trastuzumab.Front. Cardiovasc. Med.20229100084610.3389/fcvm.2022.100084636211552
    [Google Scholar]
  94. LavelleC. IsmailM.F. DohertyK. BowlerA. MohammadM.M. CassidyE.M. Association between psychological distress and cancer type in patients referred to a psycho-oncology service.Ir. Med. J.2017110657928952669
    [Google Scholar]
  95. DobretsovaA. DerakshanN. Cognitive function and emotional vulnerability in metastatic breast cancer: Moderating effects of age and social support.Psychooncology20213091563157110.1002/pon.573233991121
    [Google Scholar]
  96. LeeS.A. NamC.M. KimY.H. KimT.H. JangS.I. ParkE.C. Impact of onset of psychiatric disorders and psychiatric treatment on mortality among patients with cancer.Oncologist2020254e733e74210.1634/theoncologist.2019‑039631899576
    [Google Scholar]
  97. ParkE.M. GelberS. RosenbergS.M. SeahD.S.E. SchapiraL. ComeS.E. PartridgeA.H. Anxiety and depression in young women with metastatic breast cancer: A cross-sectional study.Psychosomatics201859325125810.1016/j.psym.2018.01.00729525523
    [Google Scholar]
  98. HashemiS.M. RafiemaneshH. AghamohammadiT. BadakhshM. AmirshahiM. SariM. BehnamfarN. RoudiniK. Prevalence of anxiety among breast cancer patients: A systematic review and meta-analysis.Breast Cancer202027216617810.1007/s12282‑019‑01031‑931828585
    [Google Scholar]
  99. BrayF. FerlayJ. SoerjomataramI. SiegelR.L. TorreL.A. JemalA. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.CA Cancer J. Clin.201868639442410.3322/caac.2149230207593
    [Google Scholar]
  100. Ruiz-CasadoA. Álvarez-BustosA. De PedroC.G. Méndez-OteroM. RomeroElíasM. Cancer-related fatigue in breast cancer survivors: A review.Clin. Breast Cancer202024111610.1016/j.clbc.2020.07.011
    [Google Scholar]
  101. SchreierA.M. JohnsonL.A. VohraN.A. MuzaffarM. KyleB. Post-treatment symptoms of pain, anxiety, sleep disturbance, and fatigue in breast cancer survivors.Pain Manag. Nurs.201920214615110.1016/j.pmn.2018.09.00530527856
    [Google Scholar]
  102. HoffmanA.J. BrintnallR.A. GivenB.A. von EyeA. JonesL.W. BrownJ.K. Using perceived self-efficacy to improve fatigue and fatigability in post-surgical lung cancer patients: A pilot randomized controlled trial.Cancer Nurs.201740111210.1097/NCC.000000000000037827135752
    [Google Scholar]
  103. HackerE.D. KimI. ParkC. PetersT. Real-time fatigue and free-living physical activity in hematopoietic stem cell transplantation cancer survivors and healthy controls: A preliminary examination of the temporal, dynamic relationship.Cancer Nurs.201740425926810.1097/NCC.000000000000045927922918
    [Google Scholar]
  104. GreshamG. DyS.M. ZipunnikovV. BrownerI.S. StudenskiS.A. SimonsickE.M. FerrucciL. SchrackJ.A. Fatigability and endurance performance in cancer survivors: Analyses from the Baltimore Longitudinal Study of Aging.Cancer201812461279128710.1002/cncr.3123829419879
    [Google Scholar]
  105. JangM.K. KimS. ParkC.G. CollinsE.G. QuinnL.T. FerransC.E. Quality of life and prolonged symptoms in Korean breast cancer survivors.Cancer Nurs.2022451E124E13310.1097/NCC.000000000000089433003122
    [Google Scholar]
  106. JiangM. MaY. YunB. WangQ. HuangC. HanL. Exercise for fatigue in breast cancer patients: An umbrella review of systematic reviews.Int. J. Nurs. Sci.20207224825410.1016/j.ijnss.2020.03.00132685623
    [Google Scholar]
  107. ZhangX. LiY. LiuD. Effects of exercise on the quality of life in breast cancer patients: A systematic review of randomized controlled trials.Support. Care Cancer201927192110.1007/s00520‑018‑4363‑230032399
    [Google Scholar]
  108. BagliaM.L. LinI.H. CartmelB. SanftT. LigibelJ. HershmanD.L. HarriganM. FerrucciL.M. LiF.Y. IrwinM.L. Endocrine‐related quality of life in a randomized trial of exercise on aromatase inhibitor–induced arthralgias in breast cancer survivors.Cancer2019125132262227110.1002/cncr.3205130840336
    [Google Scholar]
  109. CastanhelF.D. LiberaliR. Mindfulness-based stress reduction on breast cancer symptoms: Aystematic review and meta-analysis.Einstein2018164eRW438310.31744/einstein_journal/2018RW438330540032
    [Google Scholar]
  110. HallerH. WinklerM.M. KloseP. DobosG. KümmelS. CramerH. Mindfulness-based interventions for women with breast cancer: An updated systematic review and meta-analysis.Acta Oncol.201756121665167610.1080/0284186X.2017.134286228686520
    [Google Scholar]
  111. IkeuchiK. IshiguroH. NakamuraY. IzawaT. ShinkuraN. NinK. The relation between mindfulness and the fatigue of women with breast cancer: Path analysis.Biopsychosoc. Med.2020141110.1186/s13030‑020‑0175‑y32071613
    [Google Scholar]
  112. van der ValkE.S. SavasM. van RossumE.F.C. Stress and obesity: Are there more susceptible individuals?Curr. Obes. Rep.20187219320310.1007/s13679‑018‑0306‑y29663153
    [Google Scholar]
  113. SharmaV.R. GuptaG.K. SharmaA.K. BatraN. SharmaD.K. JoshiA. SharmaA.K. PI3K/Akt/mTOR intracellular pathway and breast cancer: Factors, mechanism and regulation.Curr. Pharm. Des.201723111633163810.2174/138161282366616111612521827848885
    [Google Scholar]
  114. MüllerO. NeuhannF. RazumO. Epidemiologie und Kontrollmaßnahmen bei COVID-19.Dtsch. Med. Wochenschr.20201451067067410.1055/a‑1162‑198732344440
    [Google Scholar]
  115. BrooksS.K. WebsterR.K. SmithL.E. WoodlandL. WesselyS. GreenbergN. RubinG.J. The psychological impact of quarantine and how to reduce it: Rapid review of the evidence.Lancet20203951022791292010.1016/S0140‑6736(20)30460‑832112714
    [Google Scholar]
  116. PfefferbaumB. NorthC.S. Mental health and the Covid-19 pandemic.N. Engl. J. Med.2020383651051210.1056/NEJMp200801732283003
    [Google Scholar]
  117. BäuerleA. TeufelM. MuscheV. WeismüllerB. KohlerH. HetkampM. DörrieN. SchwedaA. SkodaE.M. Increased generalized anxiety, depression and distress during the COVID-19 pandemic: A cross-sectional study in Germany.J. Public Health202042467267810.1093/pubmed/fdaa10632657323
    [Google Scholar]
  118. FrenchM.T. MortensenK. TimmingA.R. Psychological distress and coronavirus fears during the initial phase of the COVID-19 pandemic in the united states.J. Ment. Health Policy Econ.20202339310032853158
    [Google Scholar]
  119. SalariN. Hosseinian-FarA. JalaliR. Vaisi-RayganiA. RasoulpoorS. MohammadiM. RasoulpoorS. Khaledi-PavehB. Prevalence of stress, anxiety, depression among the general population during the COVID-19 pandemic: A systematic review and meta-analysis.Global. Health20201615710.1186/s12992‑020‑00589‑w32631403
    [Google Scholar]
  120. ChenX. WangL. LiuL. JiangM. WangW. ZhouX. ShaoJ. Factors associated with psychological distress among patients with breast cancer during the COVID-19 pandemic: A cross-sectional study in Wuhan, China.Support. Care Cancer20212984773478210.1007/s00520‑021‑05994‑433527226
    [Google Scholar]
  121. BridglandV.M.E. MoeckE.K. GreenD.M. SwainT.L. NaydaD.M. MatsonL.A. HutchisonN.P. TakarangiM.K.T. Why the COVID-19 pandemic is a traumatic stressor.PLoS One2021161e024014610.1371/journal.pone.024014633428630
    [Google Scholar]
  122. BargonC.A. BatenburgM.C.T. van StamL.E. Mink van der MolenD.R. van DamI.E. van der LeijF. BaasI.O. ErnstM.F. MaarseW. VermulstN. SchoenmaeckersE.J.P. van DalenT. BijlsmaR.M. Young-AfatD.A. DoeksenA. VerkooijenH.M. Impact of the COVID-19 pandemic on patient-reported outcomes of breast cancer patients and survivors.JNCI Cancer Spectr.202151pkaa10410.1093/jncics/pkaa10433437925
    [Google Scholar]
  123. LiangW. GuanW. ChenR. WangW. LiJ. XuK. LiC. AiQ. LuW. LiangH. LiS. HeJ. Cancer patients in SARS-CoV-2 infection: A nationwide analysis in China.Lancet Oncol.202021333533710.1016/S1470‑2045(20)30096‑632066541
    [Google Scholar]
  124. SigorskiD. SobczukP. OsmolaM. KućK. WalerzakA. WilkM. CiszewskiT. KopećS. HryńK. RutkowskiP. StecR. SzczylikC. BodnarL. Impact of COVID-19 on anxiety levels among patients with cancer actively treated with systemic therapy.ESMO Open202055e00097010.1136/esmoopen‑2020‑00097033097653
    [Google Scholar]
  125. SutcuogluO YaziciO OzetA OzdemirN. Harmful consequences of COVID-19 fear in patients with cancer.202313e1e102e10410.1136/bmjspcare‑2020‑002628
    [Google Scholar]
  126. GallagherS. BennettK.M. RoperL. Loneliness and depression in patients with cancer during COVID-19.J. Psychosoc. Oncol.202139344545110.1080/07347332.2020.185365333274697
    [Google Scholar]
  127. BiagioliV. AlbanesiB. BelloniS. PireddaA. CarusoR. Living with cancer in the COVID‐19 pandemic: An Italian survey on self‐isolation at home.Eur. J. Cancer Care2021302e1338510.1111/ecc.1338533289205
    [Google Scholar]
  128. ChanJ.J. SimY. OwS.G.W. LimJ.S.J. KusumawidjajaG. ZhuangQ. WongR.X. WongF.Y. TanV.K.M. TanT.J.Y. The impact of COVID-19 on and recommendations for breast cancer care: The Singapore experience.Endocr. Relat. Cancer2020279R307R32710.1530/ERC‑20‑015732544879
    [Google Scholar]
  129. SoranA. GimbelM. DiegoE. Breast cancer diagnosis, treatment and follow-up during COVID-19 pandemic.Eur. J. Breast Health2020162868810.5152/ejbh.2020.24032032285027
    [Google Scholar]
  130. CuriglianoG. CardosoM.J. PoortmansP. GentiliniO. PravettoniG. MazzoccoK. HoussamiN. PaganiO. SenkusE. CardosoF. editorial board of The Breast Recommendations for triage, prioritization and treatment of breast cancer patients during the COVID-19 pandemic.Breast20205281610.1016/j.breast.2020.04.00632334323
    [Google Scholar]
  131. de AzambujaE. TrapaniD. LoiblS. DelalogeS. SenkusE. CriscitielloC. PoortmansP. GnantM. Di CosimoS. CortesJ. CardosoF. Paluch-ShimonS. CuriglianoG. ESMO Management and treatment adapted recommendations in the COVID-19 era: Breast cancer.ESMO Open20205Suppl. 3e00079310.1136/esmoopen‑2020‑00079332439716
    [Google Scholar]
  132. KabeerK.K. JafferbhoyS. MarlaS. SoumianS. MisraV. NarayananS. BruntA.M. BruntA.M. Manoj Gowda S Breast cancer management guidelines during COVID-19 pandemic.Indian J. Surg.202082325125810.1007/s12262‑020‑02466‑732837081
    [Google Scholar]
  133. GuvenD.C. SahinT.K. AktepeO.H. YildirimH.C. AksoyS. KilickapS. Perspectives, knowledge, and fears of cancer patients about COVID-19.Front. Oncol.202010155310.3389/fonc.2020.0155333014800
    [Google Scholar]
  134. SwainstonJ. ChapmanB. GrunfeldE.A. DerakshanN. COVID-19 lockdown and its adverse impact on psychological health in breast cancer.Front. Psychol.202011203310.3389/fpsyg.2020.0203332982846
    [Google Scholar]
  135. MarinoP. TouzaniR. PakradouniJ. Ben SoussanP. GravisG. The psychological distress of cancer patients following the COVID-19 pandemic first lockdown: Results from a large french survey.Cancers2022147179410.3390/cancers1407179435406566
    [Google Scholar]
  136. CuiQ. CaiZ. LiJ. LiuZ. SunS. ChenC. WangG. The psychological pressures of breast cancer patients during the COVID-19 outbreak in China-a comparison with frontline female nurses.Front. Psychiatry20201155970110.3389/fpsyt.2020.55970133384620
    [Google Scholar]
  137. JuanjuanL. Santa-MariaC.A. HongfangF. LingchengW. PengchengZ. YuanbingX. YuyanT. ZhongchunL. BoD. MengL. QingfengY. FengY. YiT. ShengrongS. XingruiL. ChuangC. Patient-reported outcomes of patients with breast cancer during the COVID-19 outbreak in the epicenter of china: A cross-sectional survey study.Clin. Breast Cancer2020205e651e66210.1016/j.clbc.2020.06.00332709505
    [Google Scholar]
  138. RunowiczC.D. LeachC.R. HenryN.L. HenryK.S. MackeyH.T. Cowens-AlvaradoR.L. CannadyR.S. Pratt-ChapmanM.L. EdgeS.B. JacobsL.A. HurriaA. MarksL.B. LaMonteS.J. WarnerE. LymanG.H. GanzP.A. American cancer society/american society of clinical oncology breast cancer survivorship care guideline.J. Clin. Oncol.201634661163510.1200/JCO.2015.64.380926644543
    [Google Scholar]
  139. ZhouK. LiX. LiJ. LiuM. DangS. WangD. XinX. A clinical randomized controlled trial of music therapy and progressive muscle relaxation training in female breast cancer patients after radical mastectomy: Results on depression, anxiety and length of hospital stay.Eur. J. Oncol. Nurs.2015191545910.1016/j.ejon.2014.07.01025181938
    [Google Scholar]
  140. KhanS. KhanN.A. RehmanA.U. KhanI. SamoK.A. MemonA.S. Levels of depression and anxiety post-mastectomy in breast cancer patients at a public sector hospital in Karachi.Asian Pac. J. Cancer Prev.20161731337134010.7314/APJCP.2016.17.3.133727039768
    [Google Scholar]
  141. KimM.S. KimS.Y. KimJ.H. ParkB. ChoiH.G. Depression in breast cancer patients who have undergone mastectomy: A national cohort study.PLoS One2017124e017539510.1371/journal.pone.017539528394909
    [Google Scholar]
  142. KwakA. JacobsJ. HaggettD. JimenezR. PeppercornJ. Evaluation and management of insomnia in women with breast cancer.Breast Cancer Res. Treat.2020181226927710.1007/s10549‑020‑05635‑032314110
    [Google Scholar]
  143. FallerH. StrahlA. RichardM. NiehuesC. MengK. Symptoms of depression and anxiety as predictors of physical functioning in breast cancer patients. A prospective study using path analysis.Acta Oncol.201756121677168110.1080/0284186X.2017.133363028595474
    [Google Scholar]
  144. BattyG.D. RussT.C. StamatakisE. KivimäkiM. Psychological distress in relation to site specific cancer mortality: Pooling of unpublished data from 16 prospective cohort studies.BMJ201735610.1136/bmj.j108
    [Google Scholar]
  145. AhnS. OhS. KimJ. ChoiJ.S. HwangK.T. Psychological impact of type of breast cancer surgery: A national cohort study.World J. Surg.20224692224223310.1007/s00268‑022‑06585‑y35538318
    [Google Scholar]
  146. AbateS.M. ChekolY.A. BasuB. Global prevalence and determinants of preoperative anxiety among surgical patients: A systematic review and meta-analysis.Int. J. Surg. Open20202561610.1016/j.ijso.2020.05.010
    [Google Scholar]
  147. TolaY.O. ChowK.M. LiangW. Effects of non‐pharmacological interventions on preoperative anxiety and postoperative pain in patients undergoing breast cancer surgery: A systematic review.J. Clin. Nurs.20213023-243369338410.1111/jocn.1582733942405
    [Google Scholar]
  148. LinH.H. FarkasM.E. Altered circadian rhythms and breast cancer: From the human to the molecular level.Front. Endocrinol.2018921910.3389/fendo.2018.0021929780357
    [Google Scholar]
  149. GunashovaG.Y. Synthesis of silver nanoparticles using a thermophilic bacterium strain isolated from the spring Yukhari istisu of the Kalbajar region (Azerbaijan).Advances in Biology and Earth Sciences.20223198204
    [Google Scholar]
  150. KhursheedR. DuaK. VishwasS. GulatiM. JhaN.K. AldhafeeriG.M. AlanaziF.G. GohB.H. GuptaG. PaudelK.R. HansbroP.M. ChellappanD.K. SinghS.K. Biomedical applications of metallic nanoparticles in cancer: Current status and future perspectives.Biomed. Pharmacother.202215011295110.1016/j.biopha.2022.11295135447546
    [Google Scholar]
  151. EftekhariA. KryschiC. PamiesD. GulecS. AhmadianE. JanasD. DavaranS. KhalilovR. Natural and synthetic nanovectors for cancer therapy.Nanotheranostics20237323625710.7150/ntno.7756437064613
    [Google Scholar]
  152. GavasS. QuaziS. KarpińskiT.M. Nanoparticles for cancer therapy: Current progress and challenges.Nanoscale Res. Lett.202116117310.1186/s11671‑021‑03628‑634866166
    [Google Scholar]
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