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2000
Volume 15, Issue 3
  • ISSN: 2210-6812
  • E-ISSN: 2210-6820

Abstract

Introduction

Inter- and intramolecular hydroamination reactions serve as a prime example of sustainable organic chemistry. These reactions are catalytic, atom-economical (100% yield), and environmentally friendly, representing a process of fundamental simplicity where an amine is added to an alkyne substrate as well as alkenes or aromatic hydrocarbons.

Methods

To synthesize enamines with higher yield, which are important intermediates in many natural and synthetic compounds, copper supported on MoO/SiO mixed oxides was used as a highly effective catalyst for the direct hydroamination of phenylacetylene and α-naphthylamine. The catalysts were thoroughly characterized using techniques such as FT-IR, XRD, Raman, XPS, and measurements of acidic strength.

Results

Spectral data from FT-IR and Raman confirmed the successful incorporation of copper into the MoO/SiO framework. The catalytic system exhibited significant enhancements in both conversion efficiency and selectivity for the desired products, attributed to the unique properties of the Cu- MoO/SiO mixed oxide. This catalyst could be reused up to three cycles without any significant decline in activity, highlighting its environmental friendliness.

Conclusion

The method offers advantages over conventional approaches, including simplicity, reduced reaction time, complete atom economy, mild conditions, broad substrate compatibility, recyclability, and an uncomplicated product isolation process.

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A Versatile Copper Supported on MoO3/SiO2 Catalyst for Hydroamination
Nanoscience & Nanotechnology-Asia 15, E22106812369860 (2025); https://doi.org/10.2174/0122106812369860250509115517
/content/journals/nanoasi/10.2174/0122106812369860250509115517
/content/journals/nanoasi/10.2174/0122106812369860250509115517
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  • Article Type:     Research Article
Keyword(s): aromatic hydrocarbons; Cu-based MoO3/SiO2; hydroamination; Mixed oxide; phenylacetylene; α-naphthyl amine

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