Current Organic Chemistry - Volume 29, Issue 12, 2025

Natural compounds are pivotal sources for synthesizing a vast array of biologically active substances in chemistry. Camphor is one of these substances, and both enantiomers are readily obtainable and play significant roles in various synthetic and therapeutic applications. This mini-review provides information on a few synthetic routes for camphor production that have been documented over time. It presents sever Read More

Mangiferin always draws the attention of traditional as well as modern medicinal chemists because of its ease of chemical derivatization and diverse biological activities, including anticancer, anti-inflammatory, neuroprotective, antidiabetic, analgesic, antimalarial, anticonvulsant, laxative, cardiotonic, hemopoietic, antioxidant, antimicrobial, antipsychotic, anticoagulant, and antihypertensive properties. This review focuses o Read More

N-Chlorosuccinimide (NCS) is a five-membered N-containing heterocyclic molecule. This is a versatile reagent and is successfully employed for different types of reactions. Initially, this was employed for chlorination only but soon became an excellent reagent for many reactions, including halocyclizations, functional group transformations, formation of carbon-carbon bonds, etc. This review article covers representative app Read More

Carbazole derivatives possess tricyclic structure consisting of two benzene rings fused on both sides with the central pyrrole ring. These compounds diversely appear both in natural and synthetic sources. Carbazole-based compounds have a wide range of bioactivities such as antimicrobial, anticancer, antiparasitic, antihypertensive, antineuropathic, and anti-inflammatory activities. Some carbazole derivatives have been em Read More

This work is devoted to the theoretical study of methylaluminoxanes formed by the interaction of trimethylaluminum with water. The main goal of this work is to identify the most likely molecular form of methylaluminoxane formed in the reaction mixture. Quantum chemical calculations were carried out within the framework of density functional theory, at the PBE0/def2-TZVP level. The work analyzes the thermodynamic para Read More