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2000
Volume 22, Issue 4
  • ISSN: 1570-1638
  • E-ISSN: 1875-6220

Abstract

Psoriasis is a prevalent inflammatory disease affecting almost 0.5-5% of the world population. Multiple treatment approaches have been developed to manage psoriasis so far. Although concerns exist in the long-term usage of conventional and biological agents in terms of safety, effectiveness, expensiveness, and tolerability, complementary and alternative medicine (CAM) is a promising point of view for future psoriasis management. In this study, databases including Scopus, PubMed, Google Scholar, and Web of Science were searched for relevant literature on herbal medications clinically evaluated for psoriasis, especially those originating from traditional medicine. About 40 relevant papers were selected by March 2023. Most of the studies were clinical trials on poly-herbal formulations from traditional Chinese medicine (TCM). There are controversial results regarding the efficacy of these herbal formulations in psoriasis mainly due to the variation in the study design. Moreover, the probable protective mechanisms and responsible herbal metabolites of these formulations are summarized. There is a global need for more and studies based on the standard protocols in terms of the evaluation of the safety and efficacy of topical/ systemic herbal preparations for psoriasis.

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References

  1. SoleymaniT. ReddyS.M. CohenJ.M. NeimannA.L. Early recognition and treatment heralds optimal outcomes: The benefits of combined rheumatology–dermatology clinics and integrative care of psoriasis and psoriatic arthritis patients.Curr. Rheumatol. Rep.2018201110.1007/s11926‑017‑0706‑029185062
     [Google Scholar]
  2. AltekinE.R. KoçS. KarakaşM.S. YanıkoğluA. BaşarıcıI. DemirI. AlpsoyE. Determination of subclinical atherosclerosis in plaque type psoriasis patients without traditional risk factors for atherosclerosis.Turk Kardiyol. Dern. Ars.201240757458010.5543/tkda.2012.5492023363939
     [Google Scholar]
  3. LoneA. AhmadT. NaiyarA.H. Clinical evaluation of efficacy of Majoon Ushba and Roghane Hindi in the management of psoriasis: A randomized single-blind, placebo-controlled study.J. Ayurveda Integr. Med.201121263110.4103/0975‑9476.7818821731384
     [Google Scholar]
  4. NițescuD. MușetescuA. NițescuM. CostescuM. ComanO.A. Experimental research in topical psoriasis therapy (Review).Exp. Ther. Med.202122397110.3892/etm.2021.1040334335913
     [Google Scholar]
  5. LeeE.B. WuK.K. LeeM.P. BhutaniT. WuJ.J. Psoriasis risk factors and triggers.Cutis20181025S182030566552
     [Google Scholar]
  6. KimW.B. JeromeD. YeungJ. Diagnosis and management of psoriasis.Can. Fam. Physician201763427828528404701
     [Google Scholar]
  7. DamevskaK. FrançaK. LottiT. NikolovskaS. PollozhaniN. Complementary and integrative therapies for psoriasis: Looking forward.Dermatol. Ther.2018315e1262710.1111/dth.1262730133906
     [Google Scholar]
  8. CoumbeA.G. PritzkerM.R. DuprezD.A. Cardiovascular risk and psoriasis: Beyond the traditional risk factors.Am. J. Med.20141271121810.1016/j.amjmed.2013.08.01324161194
     [Google Scholar]
  9. QuX.A. FreudenbergJ.M. SanseauP. RajpalD.K. Integrative clinical transcriptomics analyses for new therapeutic intervention strategies: A psoriasis case study.Drug Discov. Today20141991364137110.1016/j.drudis.2014.03.01524662034
     [Google Scholar]
  10. SubbaiahK.V. SavithrammaN. Bio-prospecting and documentation of traditional medicinal plants used to treat itching, psoriasis and wounds by ethnic groups of kurnool district, Andhra Pradesh, India.Asian J. Pharm. Clin. Res.201252127131
     [Google Scholar]
  11. GuentherL.C. Combination therapy of biologics with traditional agents in psoriasis.Skin Therapy Lett.20111661321833461
     [Google Scholar]
  12. de AlcantaraC.C. ReicheE.M.V. SimãoA.N.C. Cytokines in psoriasis.Adv. Clin. Chem.202110017120410.1016/bs.acc.2020.04.00433453865
     [Google Scholar]
  13. BrandonA. MuftiA. Gary SibbaldR. Diagnosis and management of cutaneous psoriasis: A review.Adv. Skin Wound Care2019322586910.1097/01.ASW.0000550592.08674.4330653184
     [Google Scholar]
  14. TimisT.L. FlorianI.A. VesaS.C. MitreaD.R. OrasanR.I. An updated guide in the management of psoriasis for every practitioner.Int. J. Clin. Pract.2021758e1429010.1111/ijcp.1429033928703
     [Google Scholar]
  15. KodaliN. BlanchardI. KunamneniS. LebwohlM.G. Current management of generalized pustular psoriasis.Exp. Dermatol.20233281204121810.1111/exd.1476536779681
     [Google Scholar]
  16. KormanN.J. Management of psoriasis as a systemic disease: What is the evidence?Br. J. Dermatol.2020182484084810.1111/bjd.1824531225638
     [Google Scholar]
  17. CastrejónI. GibsonK.A. PincusT. Efficacy and safety of methotrexate in combination with other non-biologic disease-modifying antirheumatic drugs (DMARDs) in treatment of rheumatoid arthritis.Bull. Hosp. Jt. Dis.201371Suppl. 1S20S2824219037
     [Google Scholar]
  18. KalbRE Pustular psoriasis: Management.2014Available From: https://medilib.ir/uptodate/show/93554
  19. BrownstoneN.D. HongJ. MoscaM. HadelerE. LiaoW. BhutaniT. KooJ. Biologic treatments of psoriasis: An update for the clinician.Biologics202115395133623366
     [Google Scholar]
  20. TalbottW. DuffyN. Complementary and alternative medicine for psoriasis: What the dermatologist needs to know.Am. J. Clin. Dermatol.201516314716510.1007/s40257‑015‑0128‑625904522
     [Google Scholar]
  21. CapellaG.L. FinziA.F. Complementary therapy for psoriasis.Dermatol. Ther.200316216417410.1046/j.1529‑8019.2003.01625.x12919118
     [Google Scholar]
  22. KurilićM. BrajacI. MassariL.P. KaštelanM. Traditional systemic therapy-role in the treatment of psoriasis. Medicina: Glasilo Hrvatskoga liječničkoga zbora.Podružnica Rijeka.20114715358
     [Google Scholar]
  23. BissonnetteR. HoV. LangleyR.G. Safety of conventional systemic agents and biologic agents in the treatment of psoriasis.J. Cutan. Med. Surg.2009135_supplSuppl. 2S67S7610.2310/7750.2009.0002319799829
     [Google Scholar]
  24. YositaK. WannaC. KesaraN-B. Herbal medicine for psoriasis and their molecular targets: A systematic review.Afr. J. Pharm. Pharmacol.2022163275210.5897/AJPP2022.5292
     [Google Scholar]
  25. SoltaniA. Dictionary of Medicinal Plants.TehranArjmand Press2004
     [Google Scholar]
  26. GhahramanA. Matching the Old Medicinal Plant Names with Scientific Terminology.TehranTehran University Press2004
     [Google Scholar]
  27. KhareC.P. Indian Medicinal Plants.New YorkSpringe200710.1007/978‑0‑387‑70638‑2
     [Google Scholar]
  28. DamevskaK. NeloskaL. NikolovskaS. GocevG. DumaS. Complementary and alternative medicine use among patients with psoriasis.Dermatol. Ther.201427528128310.1111/dth.1213924964349
     [Google Scholar]
  29. KimJ.Y. LeeW.J. LeeS.J. KimD.W. KimT.H. JunJ.B. An investigation on the use of complementary and alternative medicine for psoriasis.Korean J. Dermatol.2010486494502
     [Google Scholar]
  30. Ben-AryeE. ZivM. FrenkelM. LaviI. RosenmanD. Complementary medicine and psoriasis: Linking the patient’s outlook with evidence-based medicine.Dermatology2003207330230710.1159/00007309414571074
     [Google Scholar]
  31. Le MoigneM. SommetA. Lapeyre-MestreM. BourrelR. MolinierL. PaulC. MontastrucJ.L. Healthcare cost impact of biological drugs compared with traditional systemic treatments in psoriasis: A cohort analysis in the French insurance database.J. Eur. Acad. Dermatol. Venereol.20142891235124410.1111/jdv.1231824236509
     [Google Scholar]
  32. RasananF.M. KenariH.M. GhassemiM. SabbaghA.J. AliaslJ. GhobadiA. Non-pharmacological treatments of psoriasis in persian medicine a narrative review.J. Pharmacopuncture20222511610.3831/KPI.2022.25.1.135371587
     [Google Scholar]
  33. KimG.W. ParkJ.M. ChinH.W. KoH.C. KimM.B. KimJ.Y. LeeS.J. KimD.W. LeeD. KimB.S. Comparative analysis of the use of complementary and alternative medicine by Korean patients with androgenetic alopecia, atopic dermatitis and psoriasis.J. Eur. Acad. Dermatol. Venereol.201327782783510.1111/j.1468‑3083.2012.04583.x22620682
     [Google Scholar]
  34. GastonL. CrombezJ-C. LassondeM. Bernier-BuzzangaJ. HodginsS. Psychological stress and psoriasis: Experimental and prospective correlational studies.Acta Derm. Venereol. Suppl. (Stockh.)199115637432048373
     [Google Scholar]
  35. TauskF. WhitmoreS.E. A pilot study of hypnosis in the treatment of patients with psoriasis.Psychother. Psychosom.199968422122510.1159/00001233610396014
     [Google Scholar]
  36. YangZ. ZengB. TangX. WangH. WangC. YanZ. HuangP. PanY. XuB. MicroRNA-146a and miR-99a are potential biomarkers for disease activity and clinical efficacy assessment in psoriasis patients treated with traditional Chinese medicine.J. Ethnopharmacol.201619472773210.1016/j.jep.2016.08.02827562321
     [Google Scholar]
  37. SongP. LysvandH. YuheY. LiuW. IversenO.J. Expression of the psoriasis-associated antigen, Pso p27, is inhibited by Traditional Chinese Medicine.J. Ethnopharmacol.2010127117117410.1016/j.jep.2009.09.03019781613
     [Google Scholar]
  38. ShanC. Treatment of psoriasis vulgaris by oral administration of Yin Xie Ping granules--clinical report of 60 cases.J. Chin. Med.2007837677
     [Google Scholar]
  39. YanY LiuW AndresP PerninC ChantalatL BriantaisP Exploratory clinical trial to evaluate the efficacy of a topical traditional Chinese herbal medicine in psoriasis vulgaris.Evid Based Complement Alternat Med.2015201571964110.1155/2015/719641
     [Google Scholar]
  40. ZhangL. BaiY. SongP. YouL. YangD. Effect of Chinese herbal medicine combined with acitretin capsule in treating psoriasis of blood-heat syndrome type.Chin. J. Integr. Med.200915214114410.1007/s11655‑009‑0145‑519407953
     [Google Scholar]
  41. HoS.G.Y. YeungC.K. ChanH.H.L. Methotrexate versus traditional Chinese medicine in psoriasis: A randomized, placebo-controlled trial to determine efficacy, safety and quality of life.Clin. Exp. Dermatol.201035771772210.1111/j.1365‑2230.2009.03693.x19925489
     [Google Scholar]
  42. MichalsenA. EddinO. SalamaA. A case series of the effects of a novel composition of a traditional natural preparation for the treatment of psoriasis.J. Tradit. Complement. Med.20166439539810.1016/j.jtcme.2015.08.00627774425
     [Google Scholar]
  43. JeonY.C. Treatment for an adult patient with psoriasis with traditional Korean medicine, especially Sa-Am acupuncture and herbal medicine.J. Acupunct. Meridian Stud.201692889210.1016/j.jams.2016.01.00827079230
     [Google Scholar]
  44. BediM.K. ShenefeltP.D. Herbal therapy in dermatology.Arch. Dermatol.2002138223224210.1001/archderm.138.2.23211843645
     [Google Scholar]
  45. CavalchiniA. ScoglioS. Complementary treatment of psoriasis with an AFA-phycocyanins product: A preliminary 10-cases study. International Medical Journal.Int. Med. J.2009163221224
     [Google Scholar]
  46. MadlandT.M. BjörkkjaerT. BrunborgL.A. FröylandL. BerstadA. BrunJ.G. Subjective improvement in patients with psoriatic arthritis after short-term oral treatment with seal oil. A pilot study with double blind comparison to soy oil.J. Rheumatol.200633230731016465662
     [Google Scholar]
  47. LinY.K. SeeL.C. HuangY.H. ChangY.C. TsouT.C. LinT.Y. LinN.L. Efficacy and safety of Indigo naturalis extract in oil (Lindioil) in treating nail psoriasis: A randomized, observer-blind, vehicle-controlled trial.Phytomedicine20142171015102010.1016/j.phymed.2014.02.01324680615
     [Google Scholar]
  48. LassusA. ForsströmS. A double-blind study comparing oleum horwathiensis with placebo in the treatment of psoriasis.J. Int. Med. Res.199119213714610.1177/0300060591019002071864450
     [Google Scholar]
  49. EllisC.N. BerberianB. SulicaV.I. Alan DoddW. JarrattM.T. KatzH.I. PrawerS. KruegerG. RexI.H.Jr WolfJ.E. A double-blind evaluation of topical capsaicin in pruritic psoriasis.J. Am. Acad. Dermatol.199329343844210.1016/0190‑9622(93)70208‑B7688774
     [Google Scholar]
  50. SyedT.A. AhmadS.A. HoltA.H. AhmadS.A. AhmadS.H. AfzalM. Management of psoriasis with Aloe vera extract in a hydrophilic cream: A placebo‐controlled, double‐blind study.Trop. Med. Int. Health19961450550910.1046/j.1365‑3156.1996.d01‑91.x8765459
     [Google Scholar]
  51. PaulsenE. KorsholmL. BrandrupF. A double‐blind, placebo‐controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris.J. Eur. Acad. Dermatol. Venereol.200519332633110.1111/j.1468‑3083.2004.01186.x15857459
     [Google Scholar]
  52. PandeyS. JhaA. KaurV. Aqueous extract of neem leaves in treatment of psoriasis vulgaris.Indian J. Dermatol. Venereol. Leprol.199460263
     [Google Scholar]
  53. BernsteinS. DonskyH. GulliverW. HamiltonD. NobelS. NormanR. Treatment of mild to moderate psoriasis with Reliéva, a Mahonia aquifolium extract--a double-blind, placebo-controlled study.Am. J. Ther.200613212112610.1097/00045391‑200603000‑0000716645428
     [Google Scholar]
  54. CuiB-N SunY-X LiuW-L Clinical efficacy of narrow band ultraviolet bin combined with yuyin recipe in treating psoriasis vulgaris.Zhongguo Zhong Xi Yi Jie He Za Zhi20082843557
     [Google Scholar]
  55. StrongA.M.M. HamillE. The effect of combined fish oil and evening primrose oil (Efamol Marine) on the remission phase of psoriasis: A 7-month double-blind randomized placebo-controlled trial.J. Dermatolog. Treat.199341333610.3109/09546639309088234
     [Google Scholar]
  56. OliwieckiS. BurtonJ.L. Evening primrose oil and marine oil in the treatment of psoriasis.Clin. Exp. Dermatol.199419212712910.1111/j.1365‑2230.1994.tb01139.x8050140
     [Google Scholar]
  57. AhmadiA. BarikbinB. NaseriM. MohagheghiM. The effect of HESA-A on psoriasis vulgaris.J. Drugs Dermatol.20087655956118561587
     [Google Scholar]
  58. GuptaA.K. EllisC.N. GoldfarbM.T. HamiltonT.A. VoorheesJ.J. The role of fish oil in psoriasis. A randomized, double-blind, placebo-controlled study to evaluate the effect of fish oil and topical corticosteroid therapy in psoriasis.Int. J. Dermatol.199029859159510.1111/j.1365‑4362.1990.tb03477.x2242951
     [Google Scholar]
  59. VealeD.J. TorleyH.I. RichardsI.M. O’DowdA. FttzsimonsC. BelchJ.J.F. SturrockR.D. A double-blind placebo controlled trial of Efamol Marine on skin and joint symptoms of psoriatic arthritis.Rheumatology (Oxford)1994331095495810.1093/rheumatology/33.10.9547921757
     [Google Scholar]
  60. StückerM. MemmelU. HoffmannM. HartungJ. AltmeyerP. Vitamin B(12) cream containing avocado oil in the therapy of plaque psoriasis.Dermatology2001203214114710.1159/00005172911586013
     [Google Scholar]
  61. SongP YanZ XuX Clinical observation on effect of compound E-bei ointment in treating plaque psoriasis.Zhongguo Zhong Xi Yi Jie He Za Zhi20072743524
     [Google Scholar]
  62. PereraGK AinaliC SemenovaE HundhausenC BarinagaG KassenD Integrative biology approach identifies cytokine targeting strategies for psoriasis.Sci. Transl. Med.20146224223ra2210.1126/scitranslmed.3007217
     [Google Scholar]
  63. SerwinA.B. SokolowskaM. ChodynickaB. Tumour necrosis factor α (TNF‐α)‐converting enzyme (TACE) and soluble TNF‐α receptor type 1 in psoriasis patients treated with narrowband ultraviolet B.Photodermatol. Photoimmunol. Photomed.200723413013410.1111/j.1600‑0781.2007.00296.x17598866
     [Google Scholar]
  64. AltemusM. RaoB. DhabharF.S. DingW. GransteinR.D. Stress-induced changes in skin barrier function in healthy women.J. Invest. Dermatol.2001117230931710.1046/j.1523‑1747.2001.01373.x11511309
     [Google Scholar]
  65. NaldiL. ParazziniF. PeliL. ChatenoudL. CainelliT. Dietary factors and the risk of psoriasis. Results of an Italian case-control study.Br. J. Dermatol.199613411011068745893
     [Google Scholar]
  66. DayanandN.D. AmuthanA. BallambatS.P. KabbekoduS.P. DeviV. Indian traditional treatments for Psoriasis: A critical appraisal of available evidence supporting efficacy.Chin. J. Integr. Med.2023291697310.1007/s11655‑022‑3519‑y35829957
     [Google Scholar]
  67. ParkerS. ZhangC.S. YuJ.J. LuC. ZhangA.L. XueC.C. Oral Chinese herbal medicine versus placebo for psoriasis vulgaris: A systematic review.J. Dermatolog. Treat.2017281213110.1080/09546634.2016.117837727366921
     [Google Scholar]
  68. MayB.H. ZhangA.L. ZhouW. LuC. DengS. XueC.C.L. Oral herbal medicines for psoriasis: A review of clinical studies.Chin. J. Integr. Med.201218317217810.1007/s11655‑012‑1008‑z22466940
     [Google Scholar]
  69. WenZ.H. XuanM.L. YanY.H. LiX.Y. YaoD.N. LiG. GuoX.F. OuA.H. LuC.J. Chinese medicine combined with calcipotriol betamethasone and calcipotriol ointment for Psoriasis vulgaris (CMCBCOP): Study protocol for a randomized controlled trial.Trials2014151217210.1186/1745‑6215‑15‑29425052161
     [Google Scholar]
  70. LiL. ZhangH. ZhongX. LuY. WeiJ. LiL. ChenH. LuC. HanL. PSORI-CM02 formula alleviates imiquimod-induced psoriasis via affecting macrophage infiltration and polarization.Life Sci.202024311723110.1016/j.lfs.2019.11723131887296
     [Google Scholar]
  71. YangX. CaiW. GuoC. ChenQ. Chinese medicine as supporting therapy for psoriasis: Past, present, and future.Chin. J. Integr. Med.202329328028810.1007/s11655‑022‑3683‑836301454
     [Google Scholar]
  72. LuoY. ChenJ. KuaiL. ZhangY. DingX. LuoY. RuY. XingM. LiH. SunX. LiB. LiX. Chinese herbal medicine for psoriasis: Evidence from 11 high-quality randomized controlled trials.Front. Pharmacol.20211159943310.3389/fphar.2020.59943333551804
     [Google Scholar]
  73. ZhouD. ChenW. LiX. DengB. XuW. QuJ. ZhangG. ZhangC. SunL. JiangC. XuJ. LiP. ChenJ. DuanY. YangZ. BaiY. LiuW. QuX. WangP. LiuJ. Evidence-based practice guideline of Chinese herbal medicine for psoriasis vulgaris (Bai Bi).Eur. J. Integr. Med.20146213514610.1016/j.eujim.2014.01.010
     [Google Scholar]
  74. RahbarM. ZareiA. RanjbarM. TabarraiM. ShirbeigiL. Etiology, clinical manifestation and natural treatments of psoriasis from the perspective of Persian medicine.Trad. Integrat. Med.20232023252
     [Google Scholar]
  75. SiefringML LuD StatesJC Van HoangM Rapid onset of multiple concurrent squamous cell carcinomas associated with the use of an arsenic-containing traditional medicine for chronic plaque psoriasis.BMJ Case Rep20182018bcr2017222645
     [Google Scholar]
  76. CoudercS. Lapeyre-MestreM. BourrelR. PaulC. MontastrucJ.L. SommetA. Infectious risk of biological drugs vs. traditional systemic treatments in moderate‐to‐severe psoriasis: A cohort analysis in the French insurance database.Fundam. Clin. Pharmacol.201832443644910.1111/fcp.1235829446857
     [Google Scholar]
  77. YamanakaK. YamamotoO. HondaT. Pathophysiology of psoriasis: A review.J. Dermatol.202148672273110.1111/1346‑8138.1591333886133
     [Google Scholar]
  78. NiculetE. RadaschinD. NastaseF. DraganescuM. BaroiuL. MiulescuM. ArbuneM. TatuA. Influence of phytochemicals in induced psoriasis (Review).Exp. Ther. Med.20202043421342410.3892/etm.2020.901332905089
     [Google Scholar]
  79. DabholkarN. RapalliV.K. SinghviG. Potential herbal constituents for psoriasis treatment as protective and effective therapy.Phytother. Res.20213552429244410.1002/ptr.697333277958
     [Google Scholar]
  80. WangS. ZhuL. XuY. QinZ. XuA. Salvianolic acid B ameliorates psoriatic changes in imiquimod-induced psoriasis on BALB/c mice by inhibiting inflammatory and keratin markers via altering phosphatidylinositol-3-kinase/protein kinase B signaling pathway.Korean J. Physiol. Pharmacol.202024321322110.4196/kjpp.2020.24.3.21332392912
     [Google Scholar]
  81. LanX.O. WangH.X. QiR.Q. XuY.Y. YuY.J. YangY. GuoH. GaoX.H. GengL. Shikonin inhibits CEBPD downregulation in IL‑17‑treated HaCaT cells and in an imiquimod‑induced psoriasis model.Mol. Med. Rep.20202232263227210.3892/mmr.2020.1131532705251
     [Google Scholar]
  82. LiX. XieX. ZhangL. MengY. LiN. WangM. ZhaiC. LiuZ. DiT. ZhangL. LiP. Hesperidin inhibits keratinocyte proliferation and imiquimod-induced psoriasis-like dermatitis via the IRS-1/ERK1/2 pathway.Life Sci.201921931132110.1016/j.lfs.2019.01.01930658103
     [Google Scholar]
  83. LiuG. WangZ. LiX. LiuR. LiB. HuangL. ChenY. ZhangC. ZhangH. LiY. ChenY. YinH. FangW. Total glucosides of paeony (TGP) alleviates constipation and intestinal inflammation in mice induced by Sjögren’s syndrome.J. Ethnopharmacol.202026011305610.1016/j.jep.2020.11305632525066
     [Google Scholar]
  84. ZhuH. WangX. WangX. LiuB. YuanY. ZuoX. Curcumin attenuates inflammation and cell apoptosis through regulating NF-κB and JAK2/STAT3 signaling pathway against acute kidney injury.Cell Cycle202019151941195110.1080/15384101.2020.178459932615888
     [Google Scholar]
  85. Sakthi PriyadarsiniS. VaniP.B. KumarP.R. A comparative review on conventional and traditional medicine in the treatment of Psoriasis.Res. J. Pharm. and Tech.2020131156425646
     [Google Scholar]
  86. ChenZ. DingW. YangX. LuT. LiuY. Isoliquiritigenin, a potential therapeutic agent for treatment of inflammation-associated diseases.J. Ethnopharmacol.2024318Pt B11705910.1016/j.jep.2023.11705937604329
     [Google Scholar]
  87. CaiS.Q. TangZ.M. XiongC. WuF.F. ZhaoJ.R. ZhangQ. WangL. ZhangX.N. ZhaoX.H. The anti-inflammatory effects of apigenin and genistein on the rat intestinal epithelial (IEC-6) cells with TNF-α stimulation in response to heat treatment.Curr. Res. Food Sci.2022591892610.1016/j.crfs.2022.05.01136686365
     [Google Scholar]
  88. AhmadS. ParveenA. ParveenB. ParveenR. Challenges and guidelines for clinical trial of herbal drugs.J. Pharm. Bioallied Sci.20157432933310.4103/0975‑7406.16803526681895
     [Google Scholar]
  89. WangX.W. Operational guidance: Information needed to support clinical trials of herbal products.Chinese J. Clin. Pharmacol Therapeut.2005125582
     [Google Scholar]
  90. SinghH.P. SharmaS. ChauhanS.B. KaurI. Clinical trials of traditional herbal medicines in India: Current status and challenges.Int J Pharmacogn.201417415421
     [Google Scholar]
  91. AmehS.J. ObodozieO.O. AbubakarM.S. GarbaM. Current phytotherapy–an inter-regional perspective on policy, research and development of herbal medicine.J. Med. Plants Res.201041515086
     [Google Scholar]
  92. SkalliS. BencheikhR.S. Safety monitoring of herb-drug interactions: A component of pharmacovigilance.Drug Saf.2012351078579110.1007/BF0326197522876741
     [Google Scholar]
  93. EkorM. The growing use of herbal medicines: Issues relating to adverse reactions and challenges in monitoring safety.Front. Pharmacol.2014417710.3389/fphar.2013.0017724454289
     [Google Scholar]
  94. ElkhawagaO.Y. ElletyM.M. MoftyS.O. GhanemM.S. MohamedA.O. Review of natural compounds for potential psoriasis treatment.Inflammopharmacology20233131183119810.1007/s10787‑023‑01178‑036995575
     [Google Scholar]
  95. GaikwadR.G. ShindeA.J. HajareA.A. Herbal treatment for management of psoriasis: An overview.Res J Pharm Technol20221531385139210.52711/0974‑360X.2022.00231
     [Google Scholar]
  96. BahugunaS. JoshiD. SinghB. SemwalN. A review on novel pharmaceutical approaches of herbal drugs in derma care.ADermatol & Cosmet JOJ.202142555631
     [Google Scholar]
  97. JyothiS.L. KrishnaK.L. Ameena ShirinV.K. SankarR. PramodK. GangadharappaH.V. Drug delivery systems for the treatment of psoriasis: Current status and prospects.J. Drug Deliv. Sci. Technol.20216210236410.1016/j.jddst.2021.102364
     [Google Scholar]
  98. KumarA. SinghS. KumarB. BaghelD.S. SatiB. ChandraP. An overview on Anti psoriasis phytocomponents used in novel drug delivery systems.AIP Conf. Proc. 2986, 03006820242986103006810.1063/5.0192537
     [Google Scholar]
/content/journals/cddt/10.2174/0115701638327441241016014503
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An Update on Clinically Evaluated Medicinal Plants for Psoriasis Management
Current Drug Discovery Technologies 22, E15701638327441 (2025); https://doi.org/10.2174/0115701638327441241016014503
/content/journals/cddt/10.2174/0115701638327441241016014503
/content/journals/cddt/10.2174/0115701638327441241016014503
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  • Article Type:     Review Article
Keyword(s): anti-inflammatory; clinical trials; Complementary medicine; herbal medicines; in vitro; psoriasis; skin disease

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