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Magnetic Nanoparticles (MNPs) have gained significant attention in biomedical applications due to their unique magnetic properties, biocompatibility, and ability to be externally controlled. Their roles in targeted drug delivery, hyperthermia, medical imaging, and biomolecule extraction position them as promising tools for advanced medical and technological applications. This review examines recent advancements in the biomedical applications of MNPs, emphasizing their potential in treating chronic diseases, improving drug delivery systems, and enhancing diagnostic techniques, such as electrochemical and optical-based immunoassays. A comprehensive literature review was conducted using relevant scientific databases to examine recent studies focusing on their structural and functional properties, biomedical applications, and technological innovations in targeted therapy and diagnostics. MNPs have demonstrated remarkable efficiency in controlled drug release, hyperthermia-based cancer treatment, and improved imaging contrast in MRI. Their integration into immunoassays has enhanced the accuracy of biosensing. However, challenges such as stability, toxicity, and scalability remain significant obstacles to clinical translation. Despite these limitations, MNPs hold immense potential to revolutionize biomedical applications. Ongoing research focuses on optimizing their performance, enhancing biocompatibility, and overcoming current barriers. Advancements in surface modification and synthesis techniques are expected to further improve their efficacy, solidifying their role in future diagnostic and therapeutic innovations.
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