A New Insight into the Synthesis and Biological Activities of Pyrazole based Derivatives

This review aims to collate literature work reported by researchers (from 1994 to 2021) to provide an overview of the available methodologies for the synthesis and diverse pharmacological activities exhibited by pyrazole based molecules. This review highlights recent reports on various routes of synthesis and potential biological evaluation studies viz. anticancer, AT (II) inhibitory, antiinflammatory activities, HIV-1-RT inhibitory, antihypertensive, herbicidal, antitubercular, insecticidal, antiviral, antimicrobial, and COX-2 inhibitory activity, etc., of pyrazole derivatives and also presents recent efforts made on this heterocyclic moiety.