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The toxicity of systemic release in common drug delivery has irreversible effects on various tissues and organs of the body. The use of programmed biopolymers sensitive to the body's physiological conditions for targeted drug delivery has attracted extensive consideration. There are numerous benefits to this approach. The need for appropriate biopolymers for drug carriers suitable for programmed cargo delivery is a crucial challenge for biologists and physicists. Summarizing such materials can be very helpful in selecting the right materials. Extensive advances and many capabilities in the field of biopolymers have led to their increasing daily use, and among other materials, this research on biopolymers. In this study, the most important polymers for programmed drug delivery are introduced. We have tried to discuss the effective properties of materials in smart stimuli-sensitive drug delivery, their advantages and disadvantages, different forms, how to use them as a smart carrier, and their absorption mechanism.
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