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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Chloroformate Free, Scalable Approach for the Synthesis of Organic Carbamates and Their Alkylation
- Source: Letters in Organic Chemistry, Volume 10, Issue 1, Jan 2013, p. 60 - 64
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- 01 Jan 2013
Abstract
A convenient method for the synthesis of organic carbamates of 2-aminopyridine without using hazardous chloroformate reagent is developed. This alternate approach for the synthesis of organic carbamates and their alkylation to 2-alkylaminopyridines is more practical and economical to be used on large scale. The amazing behavior of 2- aminopyridine helps in forming organic carbamates unlike 3-aminopyridine and 4-aminopyridine.
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