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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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One-Pot Synthesis of Furans from Isoxazolines with Iron as Reducing Agent
- Source: Letters in Organic Chemistry, Volume 7, Issue 8, Dec 2010, p. 661 - 665
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- 01 Dec 2010
Abstract
A highly efficient route to substituted furans from readily available 5-hydroxymethyl-substituted Δ2- isoxazolines is described. The transformation involves sequential reduction/hydrolysis/cyclocondensation in a one-pot reaction using iron as reducing agent under mild conditions.
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