A Facile One-Pot Synthesis of New Spiro Pyrrolidine-Oxindoles Under Ultrasonic Irradiation in DMSO-H2O

Javad Azizian; Ali Saffar-Teluri; Ali Asadi

doi:10.2174/157017806779468068

ISSN: 1570-1786
E-ISSN: 1875-6255

A Facile One-Pot Synthesis of New Spiro Pyrrolidine-Oxindoles Under Ultrasonic Irradiation in DMSO-H2O
Authors: Javad Azizian¹, Ali Saffar-Teluri² and Ali Asadi³
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¹ Department of Chemistry, Isfahan University, Isfahan, 81746-73441, Iran. ² Department of Chemistry, Isfahan University, Isfahan, 81746-73441, Iran. ³ Department of Chemistry, Isfahan University, Isfahan, 81746-73441, Iran.
Source: Letters in Organic Chemistry, Volume 3, Issue 12, Dec 2006, p. 887 - 890
DOI: https://doi.org/10.2174/157017806779468068
- Available online: 01 Dec 2006

Abstract

Ultrasonic irradiation effectively promotes the 1,3-dipolar cycloaddition reaction of azomethine ylides generated from L-phenyl alanine and isatin derivatives via the decarboxylative with N-aryl maleimides in aqueous solution under stereoselective cycloaddition via endo-transition state to give new spiro pyrrolidine cycloadducts.

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2006-12-01

2025-09-09

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Article Type: Research Article

Keyword(s): 1,3-dipolar cycloaddition; azomethine ylides; endo-transition state; spiro pyrolidines; stereoselective; Ultrasonic

A Facile One-Pot Synthesis of New Spiro Pyrrolidine-Oxindoles Under Ultrasonic Irradiation in DMSO-H2O

Abstract

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