Convenient Preparation of Original Vinylic Chlorides with Antiparasitic Potential in Quinoline Series

Pierre Verhaeghe; Pascal Rathelot; Sylvain Rault; Patrice Vanelle

doi:10.2174/157017806779467997

ISSN: 1570-1786
E-ISSN: 1875-6255

Convenient Preparation of Original Vinylic Chlorides with Antiparasitic Potential in Quinoline Series
Authors: Pierre Verhaeghe¹, Pascal Rathelot², Sylvain Rault³ and Patrice Vanelle⁴
View Affiliations Hide Affiliations

¹ Laboratoire de Chimie Organique Pharmaceutique, Faculte de Pharmacie, Universite de la Mediterranee, 27 Bd Jean Moulin, 13385 Marseille cedex 05, France. ² Laboratoire de Chimie Organique Pharmaceutique, Faculte de Pharmacie, Universite de la Mediterranee, 27 Bd Jean Moulin, 13385 Marseille cedex 05, France. ³ Laboratoire de Chimie Organique Pharmaceutique, Faculte de Pharmacie, Universite de la Mediterranee, 27 Bd Jean Moulin, 13385 Marseille cedex 05, France. ⁴ Laboratoire de Chimie Organique Pharmaceutique, Faculte de Pharmacie, Universite de la Mediterranee, 27 Bd Jean Moulin, 13385 Marseille cedex 05, France.
Source: Letters in Organic Chemistry, Volume 3, Issue 12, Dec 2006, p. 891 - 897
DOI: https://doi.org/10.2174/157017806779467997
- Available online: 01 Dec 2006

Abstract

The synthesis of various original vinylic chlorides from trichloromethylated substrates in the quinoline series is described herein. This reaction takes place under mild operating conditions via a monoelectronic transfer mechanism and presents elevated yields.

Article metrics loading...

/content/journals/loc/10.2174/157017806779467997

2006-12-01

2025-10-13

From This Site

/content/journals/loc/10.2174/157017806779467997

dcterms_title,dcterms_subject,pub_keyword

-contentType:Contributor -contentType:Concept -contentType:Institution

10

5

Full text loading...

/content/journals/loc/10.2174/157017806779467997

Article Type: Research Article

Keyword(s): antiparasitic drugs; ERC1; Quinoline; SRN1; vinylic chloride

Convenient Preparation of Original Vinylic Chlorides with Antiparasitic Potential in Quinoline Series

Abstract

From This Site

Most Read This Month

Most Cited Most Cited RSS feed

Vilsmeier-Haack Cyclisation as a Facile Synthetic Route to Thieno [2,3- b] Quinolines (Part I)

Efficient Synthesis of 4-Arylmethylene-3-methylisoxazol-5(4H)-one Derivatives Catalyzed by Malic Acid

Wonderful Natural Drugs with Surprising Nutritional Values, Rheum Species, Gifts of the Nature

Novel Derivatives Based on Zerumbone Scaffold as Potential Anticancer Inhibitors

A Review on the Syntheses and Applications of the 5H-chromeno[2,3- b]pyridines

Fe Doped Ga2O3 Nanomaterial Catalysed Green and Efficient One Pot Three Component Synthesis of Tetrahydrobenzo[b]pyran

Sulfonated Ethylenediamine Functionalized Magnetic Nanoparticles as a Highly Efficient Heterogeneous Nanocatalyst for the Green Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones

K2CO3/TBAB, a Composite of Inorganic and Organic Salts, a Novel and Powerful Media for Regioselective Michael Addition of Dihydropyrimidinones to Acrylic Esters Under and Without Solvent Conditions

Decomposition Kinetics of 1,1-Dihydroperoxycyclohexane in Some Organic Solvents

In Silico Screening of Some Anti-Cancer Drugs Against the Main Protease of COVID-19 Using Molecular Docking