Current Physical Chemistry - Current Issue
Volume 15, Issue 2, 2025
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Review: Solid Dispersion Formulation Methods and Applications in Drug Delivery
Authors: Neelam Sihag, Kavita Bahmani, Samiksha Grewal, Rajni Tanwar, Nisham Rani, Jyoti Malik and Sunita DeviAbout 44% of the active medicinal components in all previously disclosed chemical units are hydrophobic and do not extend shop because of their limited water solubility. One of the factors limiting the rate at which oral medications can reach the appropriate concentration in the systemic circulation for pharmacological action is their solubility. Our medical preparation scientists and researchers are constantly surrounded b Read More
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Vitamin C-induced DNA Cleavage Using Curcumin-loaded Fe3O4-silane Magnetic Nanoparticles
More LessIntroductionSuperparamagnetic nanoparticles are widely employed in biomedicine, especially in the fields of Magnetic Resonance Imaging (MRI), targeted medication delivery, and hyperthermia therapy. Drugs or biomolecules can be used to functionalize SPIONs, and an external magnetic field can be used to direct them to specific areas within the body. This allows for more focused medication administration with fewer sys Read More
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Physicochemical Exploration of Some Biologically Potent Molecules Prevailing in Aqueous Solution of an Anticoagulant Drug with the Manifestation of Solvation Consequences
Authors: Sourav Basu Neogi, Mahendra Nath Roy, Firoj Alam, Biraj Kumar Barman and Sanjoy SahaAimsOur research aims to uncover how solute-solvent and solute-solute interactions behave in aqueous solutions, exploring how temperature variations and concentration changes influence these interactions. This can provide deeper insights into the behavior of molecules in different environments, potentially leading to applications in fields such as drug delivery, chemical reactions, and material science.BackgroundIn t Read More
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Interaction of Triethylamine with Phenylacetylene and Exciplex Formation Study in Solutions
Authors: Sahidul Islam and Shrabani BarmanIntroductionHydrogen bonding plays a very crucial role in weak molecular complex formation. Some of the binding modes may lead to fluorescence quenching or excited state complex formation. The fluorescent property of the gas phase complex of phenylacetylene-methylamine pair is different from that of the phenylacetylene-triethylamine pair.MethodsA total of 100 mM solution of triethylamine was added in 2 Read More
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Analysis of Air Samples from the Cities of Mysuru and Madikeri
Authors: Jamuna Marilingappa and Anushka ServeshIntroductionAir pollution is a major health hazard. This study aims to investigate the concentration of the pollutants nitrogen oxides, sulfur dioxide, and respirable Particulate Matter (PM10) generated from various sources like automobiles and industries near the center of the cities in Mysuru and Madikeri.MethodsThe major pollutants, as suggested by the Karnataka State Pollution Control Board (KSPCB) in industrial areas include o Read More
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