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2000
Volume 25, Issue 8
  • ISSN: 1566-5240
  • E-ISSN: 1875-5666
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Abstract

The plague caused by has a high case fatality rate. It is often transmitted from person to person through mosquito bites, causing serious disease transmission. Due to its clinical symptoms being very similar to influenza, it is difficult to detect by people. Traditional detection methods for mainly include bacterial culture and serological identification, which are cumbersome and require high experimental conditions. Therefore, a fast and effective detection method is very important. At present, polymerase chain reaction (PCR) is one of the methods for rapid detection of . In this review, we focus on the application, advantages, and disadvantages of multiplex PCR technology in clinical detection.

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/content/journals/cmm/10.2174/0115665240321812240918095931
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Multiplex PCR System for the Diagnosis of Plague
Current Molecular Medicine 25, 939 (2025); https://doi.org/10.2174/0115665240321812240918095931
/content/journals/cmm/10.2174/0115665240321812240918095931
/content/journals/cmm/10.2174/0115665240321812240918095931
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  • Article Type:     Review Article
Keyword(s): fatality rate; mosquito bites; Multiplex PCR; plague; Yersinia pestis; zoonotic bacteria

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