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2000
Volume 32, Issue 31
  • ISSN: 0929-8673
  • E-ISSN: 1875-533X

Abstract

Increasing evidence suggests that vitamin D is one of the causes of accelerated development of Insulin Resistance (IR) and islet cell secret dysfunction. Numerous studies have shown that vitamin D can reduce inflammation, activate the transcription of the insulin receptors and related genes, and increase insulin-mediated glucose transport, thereby reducing IR. This article reviews the molecular mechanisms related to vitamin D deficiency and pancreatic β-cell dysfunction in patients with Type 2 Diabetes (T2D).

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The Regulatory Effect of Vitamin D on Pancreatic Beta Cell Secretion in Patients with Type 2 Diabetes
Curr. Med. Chem. 32, 6713 (2025); https://doi.org/10.2174/0109298673270429240805050928
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  • Article Type:     Review Article
Keyword(s): Ca2+ signaling pathway; inflammatory cytokines; insulin resistance (IR); oxidative stress; Type 2 diabetes mellitus(T2D); Vitamin D

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