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2000
Volume 3, Issue 1
  • ISSN: 2210-299X
  • E-ISSN: 2210-3007
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Abstract

Neurocysticercosis (NCC), caused by the larval stage of , is a leading cause of acquired epilepsy, contributing to 30–50% of seizure cases in endemic regions like Latin America and Southeast Asia. Infection occurs ingestion of eggs, leading to CNS cyst formation. Symptoms include seizures, headaches, hydrocephalus, and neuropsychiatric disorders, influenced by cyst location and stage. Diagnosis involves neuroimaging (MRI, CT), serological tests (EITB), and molecular methods (PCR). Treatment combines antiparasitic agents (albendazole, praziquantel) with corticosteroids, achieving up to 85% cyst resolution. Antiepileptic drugs and surgical interventions address seizures and complications like hydrocephalus. Preventive strategies, including sanitation, pig farming control, and education, are vital. Emerging therapies, such as immunomodulators and novel antiparasitic drugs, offer potential for overcoming treatment challenges. This review emphasizes advancements in NCC management and the need for integrated global efforts to mitigate its burden.

© 2025 The Author(s). Published by Bentham Science Publishers.
This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode
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2025-11-13
2026-02-02

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/content/journals/cis/10.2174/012210299X383482251027043018
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Neurocysticercosis: Clinical Manifestations, Complications, and Pharmacotherapeutic Approaches – A Comprehensive Study
Curr. Indian Sci. 3, E2210299X383482 (2025); https://doi.org/10.2174/012210299X383482251027043018
/content/journals/cis/10.2174/012210299X383482251027043018
/content/journals/cis/10.2174/012210299X383482251027043018
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  • Article Type:     Review Article
Keyword(s): Antiparasitic; CNS infections; Epilepsy; Neurocysticercosis; Taenia solium

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