Natural Products Journal, The - Volume 10, Issue 1, 2020
Volume 10, Issue 1, 2020
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An Overview of Paris polyphylla, a Highly Vulnerable Medicinal Herb of Eastern Himalayan Region for Sustainable Exploitation
Authors: Arcadius Puwein and Shiny C. ThomasBackground: Paris polyphylla has been traditionally used in China, India and Nepal to relieve various ailments such as antidote for snake bites, insect poison, relieving wounds, sore throat, etc. P. polyphylla like many plants in nature contains numerous potential bioactive compounds. Such bioactive compounds of the herb that have significant biological activities such as anticancer, antibacterial, antifungal and antiviral need to be vali Read More
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Investigation of the Biological Activities of Different Extracts from Dipsacus laciniatus Aerial Parts
Authors: Turgut Taşkın, Yeliz Akkılıç, Berna Özbek Çelik, İsmail Şenkardeş and Özlem B. ÖzakpınarBackground: The aerial parts of Dipsacus laciniatus are traditionally used in the treatment of colds as cold tea; decoction prepared from its roots and aerial parts are used for the treatment of diabetes and cancer, respectively. The extraction procedures and solvents are important steps in the processing of bioactive constituents from the plant materials. Objective: The aim of this study was to evaluate in vitro antioxidant, antimi Read More
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The Alkaloids and Bioactivities of Ethanol Extract from a Traditional Remedy of Vietnam
Background and Objective: In Vietnam, “Dai trang hoan ba Giang” (BG), which belongs to herbalist “Ba Giang”, has been one of the famous herbal remedies for ulcerative colitis and diarrhea for over 100 years. However, up to the present, the main BG’s chemical constituents have not been investigated. Therefore, this study aims to investigate the phytochemistry and antiproliferative activity of isolated compounds from BG o Read More
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α-Glucosidase Inhibitory Activity of the Extracts and Major Phytochemical Components of Smilax glabra Roxb
Authors: Phuong T.M. Nguyen, Quang V. Ngo, Minh T.H. Nguyen, Alan T. Maccarone and Stephen G. PyneBackground: A therapeutic approach to treat diabetes is to decrease postprandial hyperglycemia. α-Glucosidase inhibitors from plant sources offer an attractive strategy for the control of hyperglycemia. Smilax glabra Roxb is a medicinal plant found in Asia, including Vietnam, which is used in the treatment of chronic diseases. However, the antidiabetic activity and the identification of α-glucosidase inhibitors from this plant hav Read More
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Effect of Boswellia serrata on Rat Trachea Contractility In Vitro
More LessBackground: Boswellia serrata (family Burseraceae) has been traditionally used for the treatment of a wide variety of diseases as arthritis, inflammatory bowel diseases, and airway diseases. However, the direct bronchodilator efficacy of Boswellia serrata hasn’t been explored yet. Objective: We aimed at the present study to evaluate the direct effect of Boswellia serrata extract (BSE) on isolated rat tracheal prepara Read More
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Studies on the EC50 of Natural Monoterpenes as Fungal Inhibitors with Quantitative Structure-Activity Relationships (QSARs)
Authors: Mohamed E.I. Badawy, Entsar I. Rabea and Samir A.M. AbdelgaleilBackground: Monoterpenes are the main constituents of the essential oils obtained from plants. These natural products offered wide spectra of biological activity and extensively tested against microbial pathogens and other agricultural pests. Methods: Antifungal activity of 10 monoterpenes, including two hydrocarbons (camphene and (S)- limonene) and eight oxygenated hydrocarbons ((R)-camphor, (R)-carvone, (S)-fenchone Read More
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Antidiabetic Effect of Aqueous Corrigiola telephiifolia in Streptozotocin-Induced Diabetic Rats
Authors: Morad Hebi and Mohamed EddouksBackground: Corrigiola telephiifolia Pourr, is a perennial species, woody distributed throughout the north of Africa. This plant is used in traditional Mediterranean preparations and has many traditional uses especially treatment of diabetes. Aim/Methods: The current research was carried out to evaluate the antidiabetic effect of Aerial Parts of Aqueous Extract (APAE) of Corrigiola telephiifolia (C. telephiifolia) on both normal and st Read More
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Nrf2/HO-1 Mediated Antioxidant Activities, Cytotoxicity Analysis and LCESI/MS Profiling of Eulophia nuda L.
Authors: Vikas Nanekar, Varsha Shriram, Tushar Khare and Vinay KumarBackground: Eulophia nuda, is a highly medicinal orchid with strong antioxidant and anticancer potentials in traditional systems of medicine. But few reports are available on the scientific validation. The aim of the study was to investigate phytochemical constituents, antioxidant and cytotoxic efficacies of extracts of Eulophia nuda, and the underlying mechanisms-of-action via upregulation of nuclear transcription factor-erythro Read More
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Characterization of Galactomannan Isolated from Algerian Gleditsia triacanthos L. Seeds
Authors: Mourad Leboukh, Saoudi Aouadi and Hicham GouziBackground: The galactomannans are water-soluble carbohydrates widely used in the food, pharmaceutical, biomedical, cosmetic, textile and paper industries. Recently, a need for an alternative industrial source of galactomannans has arisen; one possible source is Honey locust (Gleditsia triacanthos), which is abundant in Algeria. Objective: The main objective of this study was to determine the physicochemical and rheolog Read More
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Fibrinolytic, Anti-Inflammatory and Cytotoxic Potentialities of Extracts and Chemical Constituents of Manglicolous Lichen, Graphis ajarekarii Patw. & C. R. Kulk
Authors: Vinay B. Tatipamula and Girija Sastry VedulaBackground: Lichens which are betide to mangroves are termed as Manglicolous Lichens (ML). As these ML are habituated under stress conditions, they are screened for unique metabolites and biological activities. Objective: The study aimed to establish the chemical and biological profile of ML, Graphis ajarekarii. Methods: The Ethyl Acetate Extract of G. ajarekarii (EAE) was subjected to chromatographic techniques and the obtai Read More
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