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Background: Self-cleaning is a potential technique in architecture environmental decontamination. Objective: The fabrication and self-cleaning property enhancement of the TiO2 hybridizing reduced graphene oxide (RGO) and codoping Si and Mo are reported. Methods: The films were deposited by a sol-gel dip-coating process. The self-cleaning properties were characterized by photocatalytic activity, photoinduced super hydrophilicity, and conductivity. Results: Incorporating RGO provided an efficient interface-induced effect, and doping Si and Mo enhanced this effect. Conclusion: Thus, the hybrid films showed remarkably enhanced self-cleaning performances. The films also show high transparency when RGO was added in the doping Si and an appropriate amount of Mo.