Biosynthesis and in vitro Antimicrobial Potential of Silver Nanoparticles Prepared using Dicoma tomentosa Plant Extract

Introduction: Green synthesis of nanoparticles has been gaining a lot of attraction owing to its property to synthesize stable nanoparticles by a simple and convenient method. Materials and Methods: The present study demonstrates the use of Dicoma tomentosa bark extract in the synthesis of silver nanoparticles (DT-AgNPs). The formation of DT-AgNPs was indicated by change of color from light brown yellow to dark brown and was confirmed by UV-vis spectroscopy. Result: The surface plasmon resonance spectra were observed at 430-480nm of AgNPs. FTIR spectra suggested that the DT-AgNPs were obtained by the action of phenolic compounds such as alkaloids, flavonoids and aromatic amines in the plant extracts. Conclusion: Several parameters (reaction time, AgNO3 concentration, extract concentration and temperature) responsible for DT-AgNPs synthesis were optimized. Further, the antibacterial potential of synthesized DT-AgNPs tested against Pseudomonas aeruginosa revealed remarkable zone of inhibition.