Mini-Reviews in Organic Chemistry - Volume 3, Issue 3, 2006

The [2+2]-cycloaddition reaction of imines with ketenes, also known as Staudinger reaction, is one of the most commonly employed synthetic entries to the β-lactam ring. Despite this, the detailed mechanism of this reaction has remained an open debate for many years. However, the application of theoretical methods has allowed a deeper understanding of many intricacies surrounding the Staudinger reaction. The ex Read More

The review will focus on recent applications of phase transfer catalysis (PTC) in organic synthesis. New developments in the synthesis of chiral phase transfer catalysts and their application in a variety of asymmetric transformations will be covered. In addition, new applications of achiral catalysts will be presented.

This mini review focuses on the synthesis of hyperbranched and dendrimers made of calix[4]arenes and thiacalix[4]arenes taken from literature. At the same time it places our investigations of calixdendrimers within the context of extant literature.

C7-substituted steroids, especially C7-substituted estradiol derivatives, have been the subject of intensive interdisciplinary studies encompassing the fields of chemistry, biochemistry and medicine. While showing the more pertinent structures with their physiological characteristics, this review will focus on the synthetic approaches to these molecules.

The use of ionic liquids as alternatives to traditional molecular solvents is a rapidly expanding field. Their many advantages, including negligible vapor pressures, tunable miscibilities and the ease of product isolation, mean that they have been considered (and shown to be effective) as solvents for a range of reactions. However, the outcomes of many of these organic processes differ on changing solvent to an ionic liqui Read More