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- ISSN: 1570-193X
- E-ISSN: 1875-6298
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Progress of Trifluoroacetoacetate in the Synthesis of Agrochemicals and Medicines with Fluorine
- Source: Mini-Reviews in Organic Chemistry, Volume 14, Issue 5, Sep 2017, p. 350 - 356
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- 01 Sep 2017
Abstract
Fluorinated medicines have become research emphasis in the fields of pesticides and medicines due to their advanced properties. Trifluoroacetoacetate (TFAAE) is an important intermediate for the synthesis of pesticide, medicine and other fluorine compounds. As a useful building block containing trifluoromethyl, TFAAE is widely used in the synthesis of heterocyclic drugs, insecticides and herbicides. In this paper, the preparation methods of TFAAE and the advanced applications in agrochemicals and medicines with fluorine are introduced in detail
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