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In this review, the natural source, structure, biological activities and the synthesis of labdanes diterpenes with highly functionalized B rings, described to date are shown. The structures for these compounds have been classified taking into account the number of oxygenated positions of the B ring. In this manner the classification has 7 groups of deoxygenated labdanes, 6 of trioxygenated and one group of the tetraoxygenated ones.