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2000
Volume 22, Issue 7
  • ISSN: 1570-193X
  • E-ISSN: 1875-6298

Abstract

Beta(β)-caryophyllene (BCP) is a naturally occurring bicyclic sesquiterpene widely present in essential oils from various spices, fruits, and both medicinal and ornamental plants. This mini-review primarily covers research progress over the past 20 years (2004-2024) regarding the anti-inflammatory activities and mechanisms of BCP, focusing on its antioxidant, immunomodulatory, analgesic, and neuroprotective properties. Experimental studies have documented a variety of pharmacological activities associated with BCP, including anti-inflammatory, antioxidant, analgesic, immunomodulatory, cardioprotective, intestinal protective, neuroprotective, and nephroprotective effects. BCP has shown significant therapeutic potential in treating diabetes, cardiovascular diseases, inflammatory bowel diseases, ischemia/reperfusion injury, inflammatory disorders, and neurodegenerative diseases.

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/content/journals/mroc/10.2174/0118756298342319241125043305
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A Mechanistic Review on the Anti-inflammatory Effects of β-caryophyllene
Mini-Reviews in Organic Chemistry 22, 671 (2025); https://doi.org/10.2174/0118756298342319241125043305
/content/journals/mroc/10.2174/0118756298342319241125043305
/content/journals/mroc/10.2174/0118756298342319241125043305
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  • Article Type:     Review Article
Keyword(s): analgesic; Beta(β)-caryophyllene (BCP); cannabinoid type 2 receptor (CB2R); immunotraction; Inflammation; neuroprotective; oxidation resistance

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