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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Green and One-Pot Three-Component Synthesis of 2,3-Dihydroquinazolin- 4(1H)-Ones Promoted by Citric Acid as Recoverable Catalyst in Water
- Source: Letters in Organic Chemistry, Volume 8, Issue 7, Sep 2011, p. 470 - 476
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- 01 Sep 2011
Abstract
Citric acid was used as green, non-toxic and reusable catalyst for the preparation of substituted 2,3- dihydroquinazolin-4(1H)ones in high purity and good yields via one-pot three-component reaction of isatoic anhydride with a variety of aldehydes and primary amines or ammonium acetate in water at 80 ° C.
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