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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Synthesis of Pyrrolizidine Derivatives in Ionic Liquid [bmim] Br
- Source: Letters in Organic Chemistry, Volume 7, Issue 6, Sep 2010, p. 472 - 474
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- 01 Sep 2010
Abstract
Pyrrolizidines were synthesized from 1,3-dipolar cycloaddition of N-substituted isatins, proline, and olefins. The highly diastereoselective and regioselective one-pot three-component cyclocondensation products were obtained in the presence of ionic liquids such as 1-buthyl-3-methlylimidazolium bromide.
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