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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Lipase Catalysed Kinetic Resolution of 2-Nitroalcohol: Total Synthesis of Taxol Side Chain and (-)-Bestatin
- Source: Letters in Organic Chemistry, Volume 4, Issue 4, Jun 2007, p. 234 - 235
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- 01 Jun 2007
Abstract
2-Nitroalcohols were efficiently resolved by Lipase catalysed transesterification process. This protocol was successfully applied to the synthesis of taxol side chain and (-)-bestatin in overall yields of 40% and 20% respectively.
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