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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Chiral Pyrrolidine-Based Salen Ligands for the Enantioselective Alkylation of Aromatic Aldehydes
- Source: Letters in Organic Chemistry, Volume 4, Issue 2, Mar 2007, p. 80 - 85
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- 01 Mar 2007
Abstract
A new type of Salen ligands derived from (2R, 3R)-N-benzyl-2,3-diaminopyrrolidine and aromatic hydroxyaldehydes was synthesized and tested in the enantioselective alkylation of aromatic aldehydes with diethylzinc, moderate selectivity being observed. This study represents the application of a new type of Zn- Salen ligands and opens the way to exploring these promising new structures in other enantioselective and biological processes.
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