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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Three-Component Synthesis of Dihydro-4-pyridones Catalyzed by Silica Sulfuric Acid
- Source: Letters in Organic Chemistry, Volume 4, Issue 2, Mar 2007, p. 129 - 133
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- 01 Mar 2007
Abstract
Three-component aza-Diels-Alder reactions of Danishefsky's diene with aldehydes and amines took place smoothly to afford dihydro-4-pyridones with high yields in the presence of a catalytic amount of silica sulfuric acid (SSA). This new protocol consistently has the advantages of operational simplicity, economic consideration, and high yield.
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