Synthesis of Dispiro [Flavanone/Chromanone/Tetralone]-Pyrrolo[1,2-a] Isoquinolinespiro[3.2'']Acenaphthen-1''-One Systems Through Three Component 1,3-Dipolar Cycloaddition Reaction

Jayadevan Jayashankaran; Rathna Durga R.S. Manian; Raghavachary Raghunathan

doi:10.2174/157017806779468022

ISSN: 1570-1786
E-ISSN: 1875-6255

Synthesis of Dispiro [Flavanone/Chromanone/Tetralone]-Pyrrolo[1,2-a] Isoquinolinespiro[3.2'']Acenaphthen-1''-One Systems Through Three Component 1,3-Dipolar Cycloaddition Reaction
Authors: Jayadevan Jayashankaran¹, Rathna Durga R.S. Manian² and Raghavachary Raghunathan³
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¹ Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai- 25, India. ² Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai- 25, India. ³ Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai- 25, India.
Source: Letters in Organic Chemistry, Volume 3, Issue 12, Dec 2006, p. 917 - 921
DOI: https://doi.org/10.2174/157017806779468022
- Available online: 01 Dec 2006

Abstract

The cycloaddition reaction of non-stabilized azomethine ylides towards (E)-3-arylidene-4- flavanone, (E)-3- arylidene-4-chromanone and (E)-2-arylidene-1-tetralone as dipolarophiles has been investigated. High degree of regioselectivity has been observed in the synthesis of a new class of functionalised dispiroheterocyclic compound containing dispiro pyrrolo-isoquinoline and acenaphthequinone framework.

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2006-12-01

2025-12-16

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Article Type: Research Article

Keyword(s): 1,3-dipole; azomethine ylide; chromanone; flavanone; quinolines; tetralone

Synthesis of Dispiro [Flavanone/Chromanone/Tetralone]-Pyrrolo[1,2-a] Isoquinolinespiro[3.2'']Acenaphthen-1''-One Systems Through Three Component 1,3-Dipolar Cycloaddition Reaction

Abstract

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