Solvent Dependent Benzylic Radical Bromination of Aromatic Sulfonyl Chlorides

Martina Gensini; Gianluca Battaglia; Rossano Nannicini; Annalisa Guerri; Maria Altamura; Laura Quartara

doi:10.2174/157017806775789958

ISSN: 1570-1786
E-ISSN: 1875-6255

Solvent Dependent Benzylic Radical Bromination of Aromatic Sulfonyl Chlorides
Authors: Martina Gensini¹, Gianluca Battaglia², Rossano Nannicini³, Annalisa Guerri⁴, Maria Altamura⁵ and Laura Quartara⁶
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¹ Dipartimento Ricerche Chimiche, Menarini Ricerche Firenze, Via Sette Santi, 3 - I-50131 Firenze, Italia. ² Dipartimento Ricerche Chimiche, Menarini Ricerche Firenze, Via Sette Santi, 3 - I-50131 Firenze, Italia. ³ Dipartimento Ricerche Chimiche, Menarini Ricerche Firenze, Via Sette Santi, 3 - I-50131 Firenze, Italia. ⁴ Dipartimento Ricerche Chimiche, Menarini Ricerche Firenze, Via Sette Santi, 3 - I-50131 Firenze, Italia. ⁵ Dipartimento Ricerche Chimiche, Menarini Ricerche Firenze, Via Sette Santi, 3 - I-50131 Firenze, Italia. ⁶ Dipartimento Ricerche Chimiche, Menarini Ricerche Firenze, Via Sette Santi, 3 - I-50131 Firenze, Italia.
Source: Letters in Organic Chemistry, Volume 3, Issue 3, Mar 2006, p. 191 - 194
DOI: https://doi.org/10.2174/157017806775789958
- Available online: 01 Mar 2006

Abstract

We have studied the solvent dependent radical bromination of toluene sulfonyl chlorides. The use of acetonitrile allows to avoid chlorinated solvents and to improve the yield and the reproducibility of the process.

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2006-03-01

2025-12-14

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Article Type: Research Article

Keyword(s): aromatic sulfonyl chloride; benzyl bromide; N-bromosuccinimide; Radical bromination

Solvent Dependent Benzylic Radical Bromination of Aromatic Sulfonyl Chlorides

Abstract

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