Clean and Facile Condensations Reaction of Indoles and Carbonyl Compounds Under Solvent-Free Conditions

Shokoufeh Mehrazma; Najmoddin Azizi; Mohammad R. Saidi

doi:10.2174/157017806775224251

ISSN: 1570-1786
E-ISSN: 1875-6255

Clean and Facile Condensations Reaction of Indoles and Carbonyl Compounds Under Solvent-Free Conditions
Authors: Shokoufeh Mehrazma¹, Najmoddin Azizi² and Mohammad R. Saidi³
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¹ Department of Chemistry, Sharif University of Technology, P. O. Box 11465-9516 Terhran, Iran. ² Department of Chemistry, Sharif University of Technology, P. O. Box 11465-9516 Terhran, Iran. ³ Department of Chemistry, Sharif University of Technology, P. O. Box 11465-9516 Terhran, Iran.
Source: Letters in Organic Chemistry, Volume 3, Issue 2, Feb 2006, p. 161 - 164
DOI: https://doi.org/10.2174/157017806775224251
- Available online: 01 Feb 2006

Abstract

A simple, rapid, atom economy and highly efficient green protocol has been developed for the reactions of indole with carbonyl compounds under solvent- free conditions. The attractive features of these procedures are the mild reaction conditions, high conversions, cleaner reaction profiles, inexpensive and environmentally friendly lithium perchlorate and short reaction times.

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2006-02-01

2025-10-31

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Article Type: Research Article

Keyword(s): atom economy; bis indole; carbonyl compounds; indole; lithium perchlorate

Clean and Facile Condensations Reaction of Indoles and Carbonyl Compounds Under Solvent-Free Conditions

Abstract

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