Pyrrole-Based Partial Peptidic Mimic of Neurotensin (8-13): Design and Synthesis (Experimental Section)

Javid H. Zaidi; Fazal Naeem; Nida Ambreen; Khalid M. Khan; Yuan-Ping Pang; Bernadette Cusack; Elliot Richelson; Awais Anwar; Wolfgang Voelter

doi:10.2174/157017806774964530

ISSN: 1570-1786
E-ISSN: 1875-6255

Pyrrole-Based Partial Peptidic Mimic of Neurotensin (8-13): Design and Synthesis (Experimental Section)
Authors: Javid H. Zaidi¹, Fazal Naeem², Nida Ambreen³, Khalid M. Khan⁴, Yuan-Ping Pang⁵, Bernadette Cusack⁶, Elliot Richelson⁷, Awais Anwar⁸ and Wolfgang Voelter⁹
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¹ Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan. ² Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan. ³ Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan. ⁴ Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan. ⁵ Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan. ⁶ Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan. ⁷ Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan. ⁸ Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan. ⁹ Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan.
Source: Letters in Organic Chemistry, Volume 3, Issue 1, Jan 2006, p. 21 - 24
DOI: https://doi.org/10.2174/157017806774964530
- Available online: 01 Jan 2006

Abstract

The synthesis of pyrrole-based semipeptidic mimic of neuropeptide neurotensin (8-13) [NT(8-13)] is described. The design of this NT mimic is based on substitution of indole by a pyrrole nucleus.

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2006-01-01

2025-08-16

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Article Type: Research Article

Keyword(s): drug design; Neurotensin; partial peptidic mimic; synthesis

Pyrrole-Based Partial Peptidic Mimic of Neurotensin (8-13): Design and Synthesis (Experimental Section)

Abstract

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