The Total Synthesis of Pitipeptolide A

Yungui Peng; Heungwing Pang; Zhengshuang Xu; Tao Ye

doi:10.2174/157017805774717481

ISSN: 1570-1786
E-ISSN: 1875-6255

The Total Synthesis of Pitipeptolide A
Authors: Yungui Peng¹, Heungwing Pang², Zhengshuang Xu³ and Tao Ye⁴
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¹ Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China ² Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China ³ Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China ⁴ Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China
Source: Letters in Organic Chemistry, Volume 2, Issue 8, Dec 2005, p. 703 - 706
DOI: https://doi.org/10.2174/157017805774717481
- Available online: 01 Dec 2005

Abstract

An efficient synthesis of the marine cyanobacterium metabolite pitipeptolide A is presented. The approach incorporates a variety of peptide coupling methods, asymmetric synthesis and macrocyclization. The route is versatile and allows scope for structural modification.

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2005-12-01

2025-09-11

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Article Type: Review Article

Keyword(s): Cyanobacteria; Depsipeptide; Lyngbya majuscula; Macrocyclization; Total synthesis

The Total Synthesis of Pitipeptolide A

Abstract

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