Functionalized, Differently Fluorinated Building-Blocks Via Michael Addition of Enamines to γ-Fluoro-α-Nitroalkenes

M. Molteni; M. Zanda

doi:10.2174/1570178054640769

ISSN: 1570-1786
E-ISSN: 1875-6255

Functionalized, Differently Fluorinated Building-Blocks Via Michael Addition of Enamines to γ-Fluoro-α-Nitroalkenes
Authors: M. Molteni¹ and M. Zanda²
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¹ C.N.R. Istituto di Chimica del Riconoscimento Molecolare, sezione "A. Quilico", and Dipartimento di Chimica, Materiali ed Ingegneria Chimica "G. Natta" del Politecnico di Milano, via Mancinelli 7, I-20131 Milano, Italy; ² C.N.R. Istituto di Chimica del Riconoscimento Molecolare, sezione "A. Quilico", and Dipartimento di Chimica, Materiali ed Ingegneria Chimica "G. Natta" del Politecnico di Milano, via Mancinelli 7, I-20131 Milano, Italy;
Source: Letters in Organic Chemistry, Volume 2, Issue 6, Sep 2005, p. 566 - 568
DOI: https://doi.org/10.2174/1570178054640769
- Available online: 01 Sep 2005

Abstract

The Michael addition of ketone-derived enamines to γ-fluoro-α-nitroalkenes provides in moderate to good isolated yields the corresponding β-fluoroalkyl γ-nitroketones, which can be reduced to β-fluoroalkyl γ- nitroalcohols.

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2005-09-01

2025-09-02

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Article Type: Review Article

Keyword(s): (nitroaldol) reaction; diels-alder; dipolar reactions; fluorinated building blocks; michael addition; mukaiyama-like conditions; nitroalkenes; tbaf

Functionalized, Differently Fluorinated Building-Blocks Via Michael Addition of Enamines to γ-Fluoro-α-Nitroalkenes

Abstract

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