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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Synthesis of New Ligands Derived from Polyphosphonates Partial Esters
- Source: Letters in Organic Chemistry, Volume 1, Issue 1, Jan 2004, p. 75 - 77
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- 01 Jan 2004
Abstract
In the search for new chelation therapy drugs for the treatment of metal intoxications, some new polyphosphonated chelating ligands have been synthesized. They were obtained by means of an Arbuzov reaction followed by addition of the corresponding dialkylphosphite. The regioselective dealkylation was then carried out by using trimethylsilyl halide.
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