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- ISSN: 1570-1808
- E-ISSN: 1875-628X
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Esters of Dehydroepiandrosterone (DHEA) as Probes for the Active Site of Type 3 17β-Hydroxysteroid Dehydrogenase (17β-HSD3)
- Source: Letters in Drug Design & Discovery, Volume 7, Issue 5, Jun 2010, p. 365 - 369
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- 01 Jun 2010
Abstract
We report the use of steroid-based compounds as probes for the active site of 17β-hydroxysteroid dehydrogenase, in particular, type 3 (17β-HSD3). Results suggest that the compounds were good inhibitors of 17β-HSD3 - a number were extremely potent with respect to the standard compounds used.
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