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- ISSN: 1570-1808
- E-ISSN: 1875-628X
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In vitro Antimicrobial Activity of Liposomes Containing Ciprofloxacin,Meropenem and Gentamicin Against Gram-Negative Clinical Bacterial Strains
- Source: Letters in Drug Design & Discovery, Volume 4, Issue 4, Jun 2007, p. 297 - 304
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- 01 Jun 2007
Abstract
The antimicrobial activity of two cationic liposomes containing three antibiotics were tested in vitro. Ciprofloxacin loaded in liposomes exhibited a 2-4 times higher antimicrobial activity compared with the free drug. The bacterial sensitivity to liposomal meropenem were similar as to free antibiotic. The least effective were the liposomes containing gentamicin.
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