Armed Imidazo [1,2-a] Pyrimidines (Pyridines): Evaluation of Antibacterial Activity

A. Anaflous; N. Benchat; M. Mimouni; S. Abouricha; T. Ben-Hadda; B. El-Bali; A. Hakkou; B. Hacht

doi:10.2174/1570180043398885

ISSN: 1570-1808
E-ISSN: 1875-628X

Armed Imidazo [1,2-a] Pyrimidines (Pyridines): Evaluation of Antibacterial Activity
Authors: A. Anaflous¹, N. Benchat², M. Mimouni³, S. Abouricha⁴, T. Ben-Hadda⁵, B. El-Bali⁶, A. Hakkou⁷ and B. Hacht⁸
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¹ Department of Chemistry, Faculty of Sciences, Oujda, 60000, Morocco ² Department of Chemistry, Faculty of Sciences, Oujda, 60000, Morocco ³ Department of Chemistry, Faculty of Sciences, Oujda, 60000, Morocco ⁴ Department of Chemistry, Faculty of Sciences, Oujda, 60000, Morocco ⁵ Department of Chemistry, Faculty of Sciences, Oujda, 60000, Morocco ⁶ Department of Chemistry, Faculty of Sciences, Oujda, 60000, Morocco ⁷ Department of Chemistry, Faculty of Sciences, Oujda, 60000, Morocco ⁸ Department of Chemistry, Faculty of Sciences, Oujda, 60000, Morocco
Source: Letters in Drug Design & Discovery, Volume 1, Issue 3, Jul 2004, p. 224 - 229
DOI: https://doi.org/10.2174/1570180043398885
- Available online: 01 Jul 2004

Abstract

Imidazopyridines and imidazopyrimidines have been prepared and tested for their antibacterial activity in vitro. Structure activity relationship studies indicate (SAR) that a modulation of both natures of arm in position 3 and atom in position 8 of these compounds has a direct impact on the antibacterial activity.

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2004-07-01

2025-09-29

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Article Type: Review Article

Keyword(s): antibacterial agents; functionalised arms; imidazo[1,2-a]pyridines; Imidazo[1,2-a]pyrimidines; mycobacterium tuberculosis; n-ligands

Armed Imidazo [1,2-a] Pyrimidines (Pyridines): Evaluation of Antibacterial Activity

Abstract

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