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2000
Volume 21, Issue 19
  • ISSN: 1570-1808
  • E-ISSN: 1875-628X

Abstract

Introduction

Marine organisms are a rich source of metabolites that can be considered functional foods and produce new medicines against metabolic syndrome, including hypertension, dyslipidemia, hyperglycemia, obesity, insulin resistance, and hyperinsulinemia.

Methods

A total of 609 publications were searching results, 283 were screened entirely, and 43 duplications were removed.

Results

These compounds, found in marine organisms such as algae, sponges, and mollusks, have vasodilatory properties, inhibit certain enzymes involved in blood pressure regulation, and exhibit anti-oxidant activity, making them promising candidates for developing hypertension treatments. Marine organisms showed an improvement in insulin sensitivity and blood glucose level regulation, suggesting their potential in developing novel therapies for diabetes management. Furthermore, some marine sources inhibit lipid accumulation, regulate metabolism, and suppress appetite, indicating their potential as therapeutic agents in combating obesity.

Conclusion

However, further studies on the pharmacological effects of marines should be performed to evaluate the potential of these compounds to produce novel drugs, but they hope this study paves and lights the way.

© 2024 Bentham Science Publishers
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/content/journals/lddd/10.2174/0115701808344500250115114637
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A Mechanistic Insight into the Effects of Marine Sources as Functional Foods Against Metabolic Syndrome: A Review Article
Letters in Drug Design & Discovery 21, 4668 (2024); https://doi.org/10.2174/0115701808344500250115114637
/content/journals/lddd/10.2174/0115701808344500250115114637
/content/journals/lddd/10.2174/0115701808344500250115114637
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  • Article Type:     Review Article
Keyword(s): algae; hypertension; insulin resistance; marines; Metabolic syndrome; mollusks

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